Qureos Mentor

Broad Institute

<div><div><div><div><h3 class="jobSectionHeader"><b>General information
</b></h3></div></div><div><div><div><div>Location
</div><div>Burlington, MA
</div></div><div><div>Ref #
</div><div>43147
</div></div><div><div>Job Family
</div><div>Research
</div></div><div><div>Workplace
</div><div>Hybrid
</div></div><div><div>Date published
</div><div>15-Oct-2025
</div></div><div><div>Time Type
</div><div>Full time
</div></div></div></div></div><div><div><div><h3 class="jobSectionHeader"><b>Description &amp; Requirements
</b></h3></div></div><div><div><div><div><p>The Broad Institute, Genomics Platform is seeking a Senior Principal Software Engineer to help lead our Data Analysis &amp; Operations team.</p><p>
This position will be instrumental in the development of our high scale cloud-based orchestration platform for running genomics pipelines and performing data delivery.</p><p>
An ideal candidate will help design, build, and maintain the necessary infrastructure, as well as, coordinate and lead the technical activities needed to support exciting new projects on the platform, for both internal and external stakeholders. This is a fast-paced role that sits in the intersection of engineering, science, and business. A successful candidate will need to work effectively across multiple departments, partners, and with a wide community of computational biologists and medical/cancer geneticists. We&rsquo;re looking for a team player that thrives on opportunity, adjusts well to change, and has the passion to make themselves, their teammates, and our partners better.</p><p>
Here at Broad our collaborators are large-scale institutions (government, industry, academic, and philanthropic) that partner with us to generate clinical and genomic data, build new algorithms, and make it all available to researchers through our open-source analysis platform. We routinely partner with organizations across the biomedical ecosystem as well as scientists in our local MIT, Harvard, and affiliated hospital neighborhood.</p><p>
Everything that goes on at the Broad, almost without exception, involves the use of specialized software. Software engineers create our advanced algorithms, deliver solid infrastructure, and high quality portals. Software engineers at the Broad Institute are highly valued and classified as Staff Scientists.<br>
<br>
<b>MINIMUM YEARS OF EXPERIENCE &amp; OTHER QUALIFICATIONS</b></p><ul><li>
Bachelor&rsquo;s or advanced degree in Computer Science or related field with 15+ years of software development experience.</li><li>
Proven ability to deliver reliable, scalable, and maintainable systems.</li><li>
Ability to design, write, and read technical documents.</li><li>
Track record of being able to deliver (or overdeliver) on time.</li><li>
Comfortable presenting and communicating technical solutions to non-technical, client stakeholders.</li><li>
Capable of understanding and translating technical requirements.</li><li>
Ability to perform effectively in a fast paced environment.</li><li>
Ability to learn new technologies and domains.</li><li>
A focus on outcomes and customer success.</li></ul><p><b><br>
SKILLS / TECHNICAL KNOWLEDGE / CERTIFICATION REQUIREMENTS:</b></p><ul><li>
Experience with cloud environments (eg. AWS, GCP)</li><li>
Familiarity with Apache Airflow a plus.</li><li>
Experience integrating complex systems together.</li><li>
Experience with multiple programming languages (especially Python and Java)</li><li>
Experience working with relational databases and in writing SQL queries.</li><li>
Experience troubleshooting and debugging complex systems.</li><li>
Experience with security practices and within regulatory environments.</li><li>
Excellent communication skills and the ability to perform effectively in a fast paced environment required.</li><li>
Must be able to handle a variety of tasks, effectively solve problems with numerous and complex variables, and be able to shift priorities rapidly.</li></ul></div></div></div></div></div></div>

Senior Principal Software Engineer

<div><div><div><div><h3 class="jobSectionHeader"><b>General information
</b></h3></div></div><div><div><div><div>Location
</div><div>Cambridge, MA
</div></div><div><div>Ref #
</div><div>43110
</div></div><div><div>Job Family
</div><div>Research
</div></div><div><div>Workplace
</div><div>On-Site
</div></div><div><div>Date published
</div><div>15-Oct-2025
</div></div><div><div>Time Type
</div><div>Full time
</div></div></div></div></div><div><div><div><h3 class="jobSectionHeader"><b>Description &amp; Requirements
</b></h3></div></div><p></p><div><div><div><div><p>We are looking for a highly motivated Junior Postdoctoral Associate to join a dynamic team investigating the physiology of thalamic circuits in animal models of psychiatric disorders. The candidate is expected to have experience in vivo electrophysiology including local field potential (LFP), single-unit, and multi-unit recordings, to study how thalamocortical dysfunction contributes to sensory, attentional, cognitive and other behavioral abnormalities. The position provides an opportunity to integrate these approaches with complementary in vivo imaging techniques (e.g. calcium imaging, GRAB sensors, functional ultrasound, or fMRI) and advanced data analysis to achieve a systems-level understanding of brain circuit function.<br>
</p><div></div><br>
The Stanley Center and the Broad Institute provide a vibrant research environment with close links to MIT, Harvard and the Harvard-affiliated hospitals across Boston. Being a member of our team will provide the opportunity for your contributions to be utilized and recognized across the vast global network of researchers in the fields of genomics and psychiatric disease research.<br>
<br>
<div></div><br>
<div><b>CHARACTERISTIC DUTIES
</b><br>
</div><ul><li>Perform in vivo electrophysiology recordings in rodent models, including LFP, single-unit, and multi-unit recordings, in thalamus and connected circuits of rodent models.
</li><li>Implement optogenetic or chemogenetic manipulations to dissect circuit-specific mechanisms.
</li><li>Analyze neural activity using advanced data processing approaches such as spike sorting, spectral analysis, connectivity metrics and state-space modeling.
</li><li>Collaborate with team members to integrate electrophysiological findings with in vivo imaging methods including calcium imaging, functional ultrasound (fUS), and fMRI.
</li><li>Rodent colony maintenance and handling.
</li><li>Prepare manuscripts and present findings at conferences.
</li><li>Provide mentorship and training for graduate students, technicians, or junior researchers.<br>
</li></ul><div></div><br>
<div><b>QUALIFICATIONS
</b><br>
</div><ul><li>Ph.D. in neurobiology, neuroscience, biomedical engineering, or a related field.
</li><li>Prior lab experience in in vivo electrophysiology (LFP, single-unit, multi-unit recordings).
</li><li>Must be comfortable working with animals.
</li><li>Proficiency in at least one scientific programming language (e.g., Python, MATLAB, R) for data analysis.
</li></ul><p></p><ul><li>Outstanding personal initiative and communication skills, and be able to work in a team.
</li><li>Exceptional organizational and time management skills, lab notebook practices and attention to detail.</li></ul></div></div></div></div></div></div><div></div>

Postdoctoral Associate - Stanley Center

<div><div><div><div><h3 class="jobSectionHeader"><b>General information
</b></h3></div></div><div><div><div><div>Location
</div><div>Cambridge, MA
</div></div><div><div>Ref #
</div><div>43150
</div></div><div><div>Job Family
</div><div>Research
</div></div><div><div>Date published
</div><div>15-Oct-2025
</div></div><div><div>Time Type
</div><div>Full time
</div></div></div></div></div><div><div><div><h3 class="jobSectionHeader"><b>Description &amp; Requirements
</b></h3></div></div><div><div><div><div><div><div>The Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard is seeking outstanding postdoctoral scholars to join a research group led by Zohreh Farsi, PhD, and Morgan Sheng, MD, PhD, Co-Director of the Stanley Center and Head of Therapeutics.
</div><div></div><div>Candidates will have the opportunity to be co-mentored by Dr. Sheng. The Stanley Center&rsquo;s mission is to improve the lives of individuals affected by serious mental illness by leveraging genetic insights to drive groundbreaking basic and translational research. In line with this mission, the Farsi/Sheng research group investigates the neurobiological mechanisms of schizophrenia and bipolar disorder using mouse models with strong human-genetic validity. This research program also provides an exciting opportunity to identify and validate novel therapeutic targets for psychiatric disorders, bridging fundamental mechanisms and translational applications.<br>
<br>
The successful candidate will join a dynamic, multidisciplinary team working on cutting-edge fundamental and translational research investigating the cellular and circuit-level mechanisms of psychiatric disorders, particularly in relation to risk genes for schizophrenia and bipolar disorders.
</div><div></div><div><br>
The research will focus on fundamental scientific questions, with the successful candidate expected to formulate hypotheses, design and execute experiments, interpret data, and write and publish original papers, often in partnership with Stanley Center scientists in the Sheng lab, other Stanley Center members and external collaborators. In particular, the successful candidate will be expected to collaborate with systems neuroscientists conducing imaging, electrophysiology and behavioral studies. Interest and/or fluency in these topics is a plus. The dynamic and collaborative environment of the Stanley Center also creates opportunities to work closely with other Therapeutics groups at the Stanley Center, allowing the successful candidate to gain valuable expertise into drug discovery and development. This postdoctoral position offers an exceptional training environment that will prepare the candidate for a successful career in academia or industry.<br>
</div><div></div><div><b>
REQUIREMENTS</b></div><ul><li>
Ph.D. in neuroscience or related field.</li><li>
0-1+ years of post graduate experience.</li><li>
Completion of at least one research project as evidenced by one or more first author research articles published or accepted in a well-recognized, peer-reviewed journal.</li><li>
Experience with bulk and single-nucleus RNA-seq analysis, brain dissection, cDNA library preparation, transcriptomics data analysis is strongly preferred.</li><li>
Additional experience with optical imaging (fiber photometry, miniscope), electrophysiology, circuit perturbation techniques (optogenetics and chemogenetics) is plus</li><li>
Experience working with rodent models, particularly involving injections, behavioral assays, surgeries and brain histology.</li><li>
Expertise with basic laboratory methods of molecular cell biology and imaging.</li><li>
Strong initiative to drive one&rsquo;s own experimental research</li><li>
Excellent communication skills</li><li>
Ability to work independently and to interact with others</li></ul></div></div></div></div></div></div></div>

Postdoctoral Associate - Neurobiology and Therapeutics of Psychiatric Disorders

<div><div><div><div><h3 class="jobSectionHeader"><b>General information
</b></h3></div></div><div><div><div><div>Location
</div><div>Cambridge, MA
</div></div><div><div>Ref #
</div><div>43129
</div></div><div><div>Job Family
</div><div>Administration
</div></div><div><div>Date published
</div><div>15-Oct-2025
</div></div><div><div>Time Type
</div><div>Full time
</div></div></div></div></div><div><div><div><h3 class="jobSectionHeader"><b>Description &amp; Requirements
</b></h3></div></div><p></p><div><div><div><div><div>Job Description Summary<br>
Responsible for cage wash processing logistics and inventory control in a state-of-the-art<br>
facility. Completes facility duties according to standard operating procedures while ensuring a<br>
consistent sanitization program.<br>
Job Description<br>
<ul><li>Operates mechanical cage wash units, bulk steam sterilizers, decontamination equipment</li></ul></div><div><br>
and material-transfer vacuum systems according to standard operating procedures and<br>
manufacturer instructions.<br>
<ul><li>Develops and implements standard operating procedures to provide a safe environment</li></ul>
and quality supplies.<br>
<ul><li>Documents, organize and maintains preventative maintenance records and manufacturer</li></ul>
specification materials.<br>
<ul><li>Processes all animal cage components &amp; related equipment through mechanical cage,</li></ul>
bottle, rack or tunnel washers.<br>
<ul><li>Responsible for maintaining adequate levels of sanitization chemicals.</li><li>Oversight of bulk bedding silos.</li><li>Maintains fixed equipment filters, air-handler and cage-top filters.</li><li>Performs quality assurance monitoring and record-keeping ensuring proper sanitation.</li><li>Must have an in-depth understanding of equipment maintenance, washing equipment</li></ul>
operation and safety components, cleaning and sterilization cycles.<br>
<ul><li>Ensures compliance with required regulations and consistently follows program and</li></ul>
institutional procedures and policies.<br>
<ul><li>Must be able to troubleshoot and report mechanical failures immediately to management.</li><li>Other related duties as assigned.</li></ul></div></div></div></div></div></div></div>

Logistics Tech I

Join Broad Institute and explore 4   exciting career opportunities. They're hiring for various roles with options for remote or on-site work. Apply today and become part of their innovative team.

Broad Institute

ABOUT_COMPANY

Senior Principal Software Engineer

Postdoctoral Associate - Stanley Center

Postdoctoral Associate - Neurobiology and Therapeutics of Psychiatric Disorders

Logistics Tech I