Qureos Mentor

Meet Life Sciences

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 Position Summary
 
 
 
 We are seeking a highly motivated Scientist II to join our Preformulation and Solid-State Chemistry group within CMC Drug Product Development. The successful candidate will contribute to the characterization and development of small-molecule new chemical entities (NCEs), focusing on solid-state properties, preformulation assessments, and material sciences to support formulation design and drug product development. This is a temporary position with the opportunity to gain hands-on experience in a fast-paced, collaborative environment.
 
 
 
 Key Responsibilities
 
 
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 Conduct preformulation studies to characterize the physicochemical properties of drug candidates (e.g., solubility, preclinical formulation (solution/ suspension), pKa, log P/D, hygroscopicity, stability).
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 Perform solid-state characterization using techniques such as XRPD, DSC, TGA, microscopy, FTIR, SEM, bulk/tapped density, contact angle, and solid-state NMR.
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 Under the guidance of a senior scientist, conduct salt, cocrystal, and polymorph screening to enable selection of optimal drug substance forms for development.
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 Conduct compatibility and excipient screening studies to support formulation development.
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 Work closely with formulation scientists to generate data guiding solid oral dosage form development.
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 Analyze, interpret, and document experimental data, ensuring high-quality technical reports.
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 Maintain laboratory notebooks and comply with all laboratory safety requirements.
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 Present data and findings in team meetings and contribute to scientific discussions.
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 Qualifications
 
 
 
 Education &amp; Experience
 
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 PhD/M.S. in Pharmaceutical Sciences, Chemistry, Materials Science, or related field with 0-2 years of relevant industry experience; or B.S. with 3-5 years of relevant experience in preformulation or solid-state chemistry.
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 Technical Skills
 
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 Hands-on experience with solid-state analytical techniques (XRPD, DSC, TGA, SEM, PLM, Surface area, True density, FTIR, HPLC, NMR spectroscopy).
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 Familiarity with solubility, dissolution, and stability testing of drug candidates.
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 Understanding of solid-state form screening (salt, cocrystal, polymorph).
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 Experience with data analysis and documentation in regulated environments.
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 Proficiency with scientific software and instrumentation for material characterization.
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 Other Skills
 
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 Strong problem-solving skills and scientific curiosity.
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 Excellent organizational and documentation practices.
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 Ability to work independently as well as in a multidisciplinary team environment.
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 Effective written and verbal communication skills
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Scientist II

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Scientist II