Qureos Mentor

Takeda Pharmaceuticals

<div>By clicking the &ldquo;Apply&rdquo; button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda&rsquo;s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.<h2 class="jobSectionHeader">
Job Description</h2>
The Rare Disease Business Manager (RDBM) is responsible for driving sales and territory growth through effective execution of sales strategies and tactics in a rare neurological sleep disorder, called narcolepsy type 1. This role involves collaboration with their Regional Business Leader and other cross-functional, customer-facing teams to ensure healthcare providers (HCPs) are well educated and that appropriate patients have access to a new therapeutic option, once approved by federal agencies.
Reporting into a Regional Business Leader, the RDBM will support a new product introduction in a new therapeutic area for Takeda. Strong execution, insights gathering, and building our Company&rsquo;s reputation will be critical to our success. The role will establish and build impactful relationships with targeted HCPs and accounts within their geographic territory. Following regulatory approval, the Rare Disease Business Manager will play a key role in generating demand for a new therapeutic option by focusing on educating and informing healthcare professionals by providing clinical information and in-depth knowledge of the product, the orexin system, and narcolepsy type 1.
How you will contribute: 
Results Focused: Demonstrates a strong sense of urgency to drive results and achieve strong performance by delivering a high level of sales effort will be necessary for a successful rare disease product introduction.<ul><li>
Clinical Expertise: Possesses and delivers exceptional disease state, product knowledge, and selling skills in working with HCPs to support product education and drive demand.</li><li>
Sales Strategy and Execution: Following approval, drive sales by implementing sales and marketing plans, leveraging strong selling skills utilizing approved, on-label materials to achieve monthly, quarterly, and annual sales goals. Execute brand strategies and manage all business-related activities within the assigned geographic territory, focusing on achieving sales goals and advancing the diagnosis and treatment of NT1.</li><li>
Specialty Customer Engagement: Builds strong relationships with, and educates healthcare professionals (HCPs), including sleep specialists, neurologists, pulmonologists, sleep centers and associated clinic staff, on disease state and approved Takeda orexin therapies.</li><li>
Strategic Analysis and Territory Planning: Strategically analyze local, regional, and national business trends and apply data to assess business opportunities and strategic priorities. Leverage market insights to appropriately tailor regional and local business strategies to market trends and customer needs.</li><li>
Communication Skills: Strong communication skills will be critical in discussions with specialty HCPs and accounts for a rare disease therapy. Utilize CRM system to document account profiles, develop pre-call plans and record post-call activities.</li><li>
Financial Responsibility: Manage a territory budget in a manner that is consistent with all Takeda compliance policies.</li><li>
Cross-Functional Collaboration: Partner with internal teams such as Patient Access, Market Access, Marketing to align on strategies and tactics that support customer and business outcomes. Collaborate with Sales and Marketing leadership to provide feedback that further supports sales tactics and performance. Foster a collaborative culture of accountability and engagement with cross-functional team members to enhance performance and impact.</li><li>
Compliance and Ethical Standards: Exemplify Takeda&rsquo;s patient-first values and commitment to upholding high standards of customer satisfaction. Adhere strictly to all Takeda compliance policies, guidelines, training and relevant laws and regulations. Demonstrate leadership and integrity by seeking clarification when uncertain on compliance matters.</li></ul>
Expected skills
Required:<ul><li>
Bachelor&rsquo;s degree &ndash; BS/BA.</li><li>
3+ years of successful selling experience in pharmaceutical, biotech or medical device and/or relevant clinical or industry experience.; OR 2+years of successful selling experience at Takeda.</li><li>
Excellent verbal and written communication skills.</li><li>
Proven ability to navigate complex selling environment and influence across various decision makers in key accounts.</li><li>
Strong business acumen and strategic planning skills to identify and execute on selling opportunities.</li><li>
Demonstrated territory planning, strategic account management and prioritization skills. Ability to interpret analytical data to create effective sales strategies.</li><li>
Strong collaborative skills and ability to work within a matrix of cross functional partners on behalf of the customers served.</li><li>
Understanding of payer access and reimbursement at territory, regional, and state levels.</li><li>
Adaptability to changing market conditions and customer needs.</li><li>
Demonstrated learning agility with ability to successfully develop and compliantly apply clinical expertise and selling skills.</li><li>
Must reside within the territory or within close proximity to assigned geography.</li></ul>
Preferred<ul><li>
5+ years of pharmaceutical sales experience, preferably in rare disease or sleep disorders</li><li>
Sales experience with pharmaceutical or biologic products requiring coordination with patient access and market access teams.</li><li>
Relevant clinical or industry experience.</li><li>
Consultative / needs-based selling skills.</li><li>
Experience working in a highly regulated marketplace.</li><li>
Adept at leveraging emerging technologies, digital tools, and openness to AI-enabled processes.</li></ul>
LICENSES/CERTIFICATIONS:
Valid Driver's License
TRAVEL REQUIREMENTS:<ul><li>
Ability to drive and/or fly to accounts and occasional business meetings</li><li>
Some overnight travel of up to 25-50% may be required depending on geographic assignment</li></ul>
TRAINING REQUIREMENTS:
This position and continued employment is contingent upon the employee successfully passing mandatory product training which includes written and oral examinations.
External Takeda Hires Only: During that training period, the employee will be classified as a non-exempt employee and will be eligible for overtime during the training period only in accordance with applicable federal and/or state law but the employee will not be eligible for any Takeda related sales incentive programs and/or other production based bonuses. The training period will consist of live instruction, independent study, role play, and other training related activities which should take no more than 8 hours per day and 40 hours total in a workweek.
After successful passage of the mandatory product training examinations, the employee will be transitioned to exempt status and will no longer be eligible for overtime. They will then be paid on a bi-weekly basis and eligible to participate in various Takeda related sales incentive programs and/or contests.
Takeda Compensation and Benefits Summary<div>
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.</div>
For Location:
USA - NY - Virtual
U.S. Hourly Wage Range:
$66.11 - $90.91 
The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.<h2 class="jobSectionHeader">
Locations</h2>
USA - NY - Virtual<h2 class="jobSectionHeader">
Worker Type</h2>
Employee<h2 class="jobSectionHeader">
Worker Sub-Type</h2>
Regular<h2 class="jobSectionHeader">
Time Type</h2>
Full time
Job Exempt
No
#LI-Remote</div>

Rare Disease Business Manager, Sleep Disorders (Brooklyn, NY)

<div>By clicking the &ldquo;Apply&rdquo; button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda&rsquo;s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.<h2 class="jobSectionHeader">
Job Description</h2>
Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Associate Director, Global Program Management in our Cambridge, MA office.
At Takeda, we are transforming the pharmaceutical industry through our R&amp;D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Here, you will be a vital contributor to our inspiring, bold mission.
OBJECTIVES:
Provides global program management and matrixed leadership to global, cross-functional, cross-divisional teams to drive development and deliver results in early to late-phase major development and/or lifecycle management programs (including established/marketed products) to meet Takeda strategic objectives.<ul><li>
Responsibilities include providing strategic direction and translating the cross-divisional, integrated Global Product Team (GPT) strategy into an efficiently executable plan; predicting and planning solutions to achieve program goals and objectives; driving clarity and removing barriers to ensure team success; interfacing with management and influencing decision-making, proactive management and mitigation of development risks, and ensuring appropriate communication and interface with internal governance.</li><li>
Works closely with the Global Program Leader (GPL), as well as other R&amp;D and Commercial functions to ensure that the scientific and commercial strategies are incorporated into the asset strategy and integrated development plan.</li><li>
May lead key initiatives that have cross-functional or cross-divisional impact that are critical to the objectives of the Therapeutic Area Unit (TAU), Center of Operational Performance (CoOP), CMSO and/or global business objectives.</li><li>
Play a key role in ensuring team effectiveness, partnering with GPL and CoOP to administer team health checks to generate insights, plan &amp; execute appropriate follow-up actions.</li><li>
Identifies and drives innovative process improvements with significant organizational impact and manages, as needed, non-project responsibilities, which can include processes and system optimizations.</li><li>
May have direct people management responsibilities.</li></ul>
ACCOUNTABILITIES:
Strategic Direction<ul><li>
Partners with GPL to coordinate and facilitate GPT or joint Program Team (for partnered Alliance programs) and/or other cross-functional teams to develop and maintain the asset strategy and integrated development plan in conjuction with TAU and commercial strategy, lifecycle management requirements, and evidence generation/publication needs.</li><li>
Proactively identifies resource requirements necessary to progress asset development in alignment with TAU or enterprise business objectives.</li><li>
Drives clarity with GPT and other relevant stakeholders to communicate asset strategic imperatives to ensure appropriate prioritization.</li></ul>
Program Execution<ul><li>
Identifies ways to optimize program execution without compromise to patients or compliance.</li><li>
Accountable to maintain the integrated program level plan, ensuring delivery of critical path activities to progress asset development.</li></ul>
Program Operational Excellence<ul><li>
Ensures asset strategy and integrated development plan are aligned with the GPT, have a patient-centric focus, incorporate innovative approaches that are meaningful to patients, HCPs, regulators &amp; payers, and adhere to the highest standards of operational excellence in drug development and life cycle management.</li><li>
Manages the strategic GPT forum and assigned subteams to ensure progress of asset development. This includes establishing meeting agendas, facilitating effective team discussions, driving to clear and timely team actions and decisions, driving and holding team members accountable for action follow-through.</li><li>
Ensures team effectiveness through team health checks with development and appropriate follow-through on action plans to boost team productivity.</li><li>
Partners with the GPL to provide financial oversight of the program including global, cross-divisional budgets. Includes consolidation, vetting and prioritization of GPT spending to deliver critical path activities.</li></ul>
Risk Management<ul><li>
Proactively addresses and removes barriers to program progress, keeping leadership informed of critical considerations (e.g., resources, performance).</li><li>
Proactively identify potential issues or obstacles and achieves resolution or plans contingencies. Follow issues through to resolution ensuring that all key stakeholders are informed of outcomes and program implications.</li><li>
Provides clarity and direction in urgent or unexpected situations. Independently resolves complex issues and competing priorities that may impact achievement of goals, creates mitigation plans and drives to resolution.</li></ul>
Communication and Reporting<ul><li>
Manages scheduled and ad-hoc program status reporting, citing progress to program goals/KPIs, proactively identifying risk with planned mitigation(s), and providing rationale for timeline and budget variances.</li><li>
Participate in annual portfolio analyses to communicate program development progress, opportunities, and risks to Senior &amp; Executive Management.</li><li>
Responsible for coordinating preparation efforts for governance engagement to support and drive asset objectives and deliverables.</li><li>
Practively manages key stakeholders and facilitates relevant communications to appropriate cross-regional, cross-functional, cross-divisional and Alliance partners</li></ul>
Other Accountabilities<ul><li>
Provides direction and mentors junior colleagues to work strategically and drive results; identifies opportunities for junior PMs to demonstrate their abilities; uses effective coaching techniques to refocus energy and address barriers to success; leads by example</li><li>
May have responsibility for line management of Sr. Manager and/or Associate Director level GPMs as well as contractors within the GPM function.</li><li>
May support Business Development in-licensing activities to ensure appropriate technical assessment, including development costs and timelines, to support the business case of potential in-licensed compounds.</li></ul>
EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS:
Education<ul><li>
Bachelor&rsquo;s Degree science or business-related field</li><li>
Advanced degree in science or business is preferred</li></ul>
Experience<ul><li>
Minimum of 8-10 years of strong pharmaceutical industry experience and drug development in all phases of development with significant experience within related functions (e.g. Clinical Science, Clinical Operations, Research, Regulatory, CMC, Marketing)</li><li>
Minimum of 5 years program management experience leading complex pharmaceutical projects in a multi-disciplinary, global environment</li></ul><ul><li>
Demonstrated ability to positively influence outcomes, key project decisions, and strategic problem-solving</li><li>
Proven ability to communicate clearly and present key information objectively to all levels of the organization including executive management</li></ul><ul><li>
Substantial experience in intercultural cooperation</li><li>
Modest people management experience and/or proven leadership experience in managing global, matrix teams</li></ul>
Knowledge and Skills<ul><li>
Matrix program leadership and management skills are required</li><li>
Therapeutic Area preferable but not required</li></ul><ul><li>
Strong influencing skills</li><li>
Ability to predict risks and independently propose solutions and appropriate mitigation plan</li><li>
Highly effective presentation, written and verbal communication skills</li><li>
Ability to drive decision-making within cross-functional &amp; cross-cultural, global team structures</li><li>
Simultaneous management of multiple tasks of varied complexity</li><li>
Flexibility, tolerance and diplomacy to best manage change and differing opinions</li><li>
Ability to work in a virtual setting/across time-zones, i.e., making effective use of communication tools (WebEx, TelePresence, telephone and video conferencing, etc.)</li><li>
Ability to work in a highly complex, multi-cultural, environment</li><li>
Excellent organizational skills</li><li>
Experience with Microsoft Project Professional, Excel, PowerPoint &amp; Word</li><li>
Fluent in English</li></ul>
This position is currently classified as &ldquo; hybrid&rdquo; in accordance with Takeda&rsquo;s Hybrid and Remote Work policy.
Empowering Our People to Shine
Discover more at takedajobs.com
No Phone Calls or Recruiters Please.
#LI-JV2
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - MA - Cambridge - Kendall Square - 500
U.S. Base Salary Range:
$154,400.00 - $242,550.00 
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.<h2 class="jobSectionHeader">
Locations</h2>
USA - MA - Cambridge - Kendall Square - 500<h2 class="jobSectionHeader">
Worker Type</h2>
Employee<h2 class="jobSectionHeader">
Worker Sub-Type</h2>
Regular<h2 class="jobSectionHeader">
Time Type</h2>
Full time
Job Exempt
Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.</div>

Associate Director, Global Program Management, Neuroscience TAU

<div>By clicking the &ldquo;Apply&rdquo; button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda&rsquo;s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.<h2 class="jobSectionHeader">
Job Description</h2><div><div>
About the role:</div><div>
Manage the end-to-end promotional content creation process for assigned therapeutic areas (TAs) by overseeing agency partnerships, ensuring compliance, and delivering high-quality, scalable assets that align with brand strategy and business objectives</div><div>
How you will contribute:</div><div><ul><li>
Content Production Management: Coordinate the day-to-day execution of promotional content production across all channels, ensuring timely delivery of high-quality assets based on strategic input from Brand teams and direction from the Commercial Content Lead
</li></ul></div><div><ul><li>Agency Collaboration: Act as the operational point of contact for content agency partners, managing day-to-day operations for content creation, adaptation, and derivative asset production, while ensuring adherence to quality standards and timelines
</li></ul></div><div><ul><li>MLR and Compliance Support: Collaborate with the Promotional Review Team (PRT) to ensure all content undergoes appropriate review and complies with regulatory, legal, and compliance requirements and is Medically accurate
</li></ul></div><div><ul><li>Workflow Coordination: Work with Agile Coaches and Brand teams to coordinate sprint-level workflows and handoffs, tracking capacity and progress to keep work moving and commitments on track
</li></ul></div><div><ul><li>Data and Asset Management: Ensure proper tagging (by agency partners), organization, and management of content assets in digital systems to enable tracking and reporting
</li></ul></div><div><ul><li>TA Familiarity: Rapidly develop a working knowledge of assigned therapeutic areas, brand strategy, and customer dynamics to ensure content decisions are contextually aligned and commercially relevant</li></ul></div><div> 
Qualifications and essential experience, attributes, skills, and knowledge
</div><div><ul><li>Bachelor&rsquo;s degree required; MBA or advanced degree preferred.</li></ul></div><div><ul><li>
5&ndash;7+ years of experience in pharmaceutical/biopharma/healthcare marketing, communications, advertising</li></ul></div><div><ul><li>
Experience working with promotional content and MLR review</li></ul></div><div><ul><li>
Experience managing creation of:</li></ul></div><div><ul><li>
HCP promotional materials</li></ul></div></div><div><div><ul><li>
Digital assets</li></ul></div><div><ul><li>
Sales rep materials</li></ul></div><div><ul><li>
Email / CRM content</li></ul></div><div><ul><li>
Websites or modular content</li></ul></div><div><ul><li>
Strong project management, organizational, and communication skills.</li></ul></div><div><ul><li>
Experience with budget management, vendor contracts, and financial oversight.</li></ul></div><div><ul><li>
 Experience submitting assets through Veeva</li></ul></div><div><ul><li>
Worked on MLR review cycles</li></ul></div><div><ul><li>
 Managed digital and HCP promotional content production</li></ul></div><div>
 More about us: 
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. 
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.</div></div>
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Lexington, MA
U.S. Base Salary Range:
$116,000.00 - $182,270.00 
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.<h2 class="jobSectionHeader">
Locations</h2>
Lexington, MA<h2 class="jobSectionHeader">
Worker Type</h2>
Employee<h2 class="jobSectionHeader">
Worker Sub-Type</h2>
Regular<h2 class="jobSectionHeader">
Time Type</h2>
Full time
Job Exempt
Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.</div>

Manager, GI Content Creator

<div>By clicking the &ldquo;Apply&rdquo; button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda&rsquo;s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.<h2 class="jobSectionHeader">
Job Description</h2>
Takeda Research is constructing a Lab of Tomorrow built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and Discovery Automation &amp; Robotics (DAR).
AIRx will have a group of a dedicated group of experienced biologic drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models for large molecule discovery and deliver candidates to the clinic at industry leading speed and success rates.<h2 class="jobSectionHeader">
Purpose</h2>
In AIRx, every go/no-go decision carries real cost, and the safety call is the one that stops a program or sends it forward. As Nonclinical Safety Lead, you own the safety strategy that supports every candidate in the AIRx portfolio: designing the nonclinical safety package, directing CRO execution with precision, and ensuring that the data generated at CROs is interpretable, AI-ready, and decisive.
It is a scientific strategy role combined with a hands-on project toxicologist function in a unit that moves at biotech speed. You will be embedded in the DMTA cycle from early hit assessment through IND-enabling studies, working alongside medicinal chemists, computational scientists, and biologists to flag liabilities early, design around them fast, and build the nonclinical dossier that gives programs the best possible chance in the clinic.
The right person for this role is a seasoned nonclinical safety expert who is as comfortable directing and critically interpreting study packages as they are challenging a SAR hypothesis on the basis of a structural alert; and who sees AI-enabled data integration not as a future concept but as how they want to work today.<h2 class="jobSectionHeader">
AIRx Leadership Capabilities</h2><ul><li>
Thrive in an environment with laser focus on delivery of differentiated candidates to the clinic</li><li>
Accountable leaders who act with decisive judgment; they show agency, move work forward without waiting to be told, and make sound decisions with urgency</li><li>
Builders of momentum, not bureaucracy; they advance programs through expertise, surface the best thinking quickly, and create conditions for decisions</li><li>
Generative thinkers with a learning orientation &mdash; curious, constructive, truth-seeking. They embody &quot;learn-it-all vs know-it-all&quot;, fail fast and learn faster, and create inclusive environments with the psychological safety to surface all contributions</li><li>
Systems thinkers who look forward &mdash; they see the whole R&amp;D system, anticipate inflection points, and lead through cross-disciplinary integration</li><li>
Values-led under pressure &mdash; they act in the best interests of patients and Takeda and are always team players</li><li>
Change leaders who challenge norms and empower others &mdash; they are role models for the culture AIRx is creating; challenging when the norm reduces impact and staying ready for rapid shifts</li><li>
Fluent in the hybrid biopharma reality &mdash; comfortable at the wet/dry interface of lab science and AI/data/engineering; instinctive about where value inflects across the discovery-to-development continuum</li><li>
Externally oriented &mdash; they tap into external KOL networks, contribute meaningfully to business development, and monitor the competitive and regulatory landscape to inform decisions</li><li>
Deep experts in their domain &mdash; with in-depth, current knowledge of their discipline and a restless drive to advance it</li><li>
Impactful communicators who create alignment &mdash; confident in high-stakes, ambiguous settings; bridging across boundaries and keeping colleagues anchored to the mission</li></ul><h2 class="jobSectionHeader">
Nonclinical Safety Lead Accountabilities</h2><ul><li>
Own the nonclinical safety strategy across the AIRx portfolio, including small molecule and biologics projects, from early screening through IND-enabling studies; ensure every program has a clear, risk-proportionate toxicology plan aligned to its clinical hypothesis and regulatory pathway</li><li>
Design and oversee CRO- or in-house executed in vitro and in vivo safety studies; write and review study protocols, critically interpret data packages, and determine their implications for program progression</li><li>
Integrate safety data into AI-enabled DMTA cycles; partner with Medicinal and Computational Chemists to flag structural liabilities early, interpret ADME-tox outputs, and feed clean, standardized safety data into AIRx data systems (TetraScience, SAIL) for AI/ML use</li><li>
Lead early safety screening cascade design including: in silico toxicity prediction, off-target liability assessment, geno- and organ-toxicity screening, and reactive metabolite assessment &mdash; to inform design decisions before significant synthesis investment</li><li>
Oversee repeat-dose, genetic toxicology, safety pharmacology studies as programs progress; ensure GLP studies are scoped correctly and delivered on time and to quality</li><li>
Author and review nonclinical sections of INDs, CTAs, and key regulatory briefing documents; serve as Takeda's scientific representative in regulatory interactions concerning non-clinical safety</li><li>
Collaborate closely with DMPK to integrate PK/TK, metabolite profiling, and safety margin calculations into program decision frameworks; ensure PK-PD-toxicity relationships are clearly articulated and expressed in safety margins to clinically meaningful doses</li><li>
Stay current with evolving regulatory guidance (FDA, EMA, ICH) on nonclinical safety requirements; proactively assess and communicate implications for AIRx program timelines and study designs</li><li>
Contribute to the scientific rigor and AI-readiness of AIRx safety data &mdash; ensuring assay outputs are standardized, annotated, and structured for downstream model training and insights generation</li><li>
Shape how nonclinical safety is practiced in the AIRx model &mdash; your approach to early liability identification and CRO direction will become part of the template Takeda Research scales across its future AI-enabled operating model</li></ul><h2 class="jobSectionHeader">
Qualifications &amp; Competencies</h2><ul><li>
Expected Requirements:</li><li>
PhD in toxicology, pharmacology, biochemistry, or closely related discipline; board certification or fellowship in toxicology (DABT, ERT, or equivalent) strongly preferred</li><li>
12&ndash;15+ years of pharmaceutical drug discovery experience with a strong, hands-on track record in nonclinical safety strategy and IND-enabling toxicology for small molecule and biologics projects</li><li>
Strong ability to work and make safety-related decisions independently; readiness to seek external expert advice when necessary</li><li>
Expert knowledge of ICH guidelines, FDA and EMA non-clinical expectations, and the regulatory context governing non-clinical safety for first-in-human studies</li><li>
Deep expertise in genetic toxicology, repeat-dose toxicology, safety pharmacology (core battery and supplemental), immunotoxicology; working knowledge of phototoxicity, reproductive and developmental toxicology</li><li>
Proficiency in early safety screening: in silico structural alert tools, in vitro hepatotoxicity, cardiotoxicity and genotoxicity assays, off-target liability and reactive metabolite assessment, immunogenicity assessment and ADME-tox profiling</li><li>
Track record designing, directing, and critically interpreting externalized CRO GLP and non-GLP safety study packages</li><li>
Ability to succinctly and effectively summarize the content and safety implications from nonclinical studies for regulatory submissions, including components for IBs and clinical protocols</li><li>
Experience working at the DMPK/toxicology interface: TK analysis, metabolite profiling, safety margin assessment, and species selection rationale</li><li>
AI/ML data literacy; comfortable working with large multi-source safety datasets and integrating in silico predictions with experimental outputs in a DMTA context</li><li>
Deep experience in at least one of Takeda's priority therapeutic areas (oncology, neuroscience, gastroenterology/immune/inflammation)</li><li>
Excellent cross-functional collaboration and scientific communication skills; able to translate complex toxicology findings into clear program implications for non-specialist audiences and governance forums</li></ul>
ADDITIONAL INFORMATION<ul><li>
The position will be based in Cambridge, MA. This position is currently classified as &ldquo;hybrid&rdquo; by Takeda&rsquo;s Hybrid and Remote Work policy</li></ul>
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MA
U.S. Base Salary Range:
$212,000.00 - $333,190.00 
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.<h2 class="jobSectionHeader">
Locations</h2>
Boston, MA<h2 class="jobSectionHeader">
Worker Type</h2>
Employee<h2 class="jobSectionHeader">
Worker Sub-Type</h2>
Regular<h2 class="jobSectionHeader">
Time Type</h2>
Job Exempt
Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.</div>

AIRx, Sr. Director, Nonclinical Safety Lead

<div>By clicking the &ldquo;Apply&rdquo; button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda&rsquo;s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.<h2 class="jobSectionHeader">
Job Description</h2>
Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Medical Director, Clinical Science, Neuroscience- Psychiatry in our Cambridge, MA office.
At Takeda, we are transforming the pharmaceutical industry through our R&amp;D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Here, you will be a vital contributor to our inspiring, bold mission.
POSITION OBJECTIVES:
The Medical Director leads and drives strategy for the overall global (US/EU/Japan/China) clinical development taking into consideration the medical, scientific, regulatory and commercial issues for assigned Takeda pipeline compounds. Leads a multi-disciplinary, multi-regional, matrix team through highly complex decisions. This individual has the ultimate responsibility for development decisions assessing and integrating the input from various disciplines to create, maintain, and execute a global clinical development plan that will result in the regulatory approval of the assigned compound in multiple regions. Applies clinical/medical decision making to clinical development issues. This individual interacts with and influences R&amp;D and Global Product Launch &amp; Strategy (GPLS) senior leadership decision-making for the projects by setting strategic direction. Success or failure directly translates to the ability of TGRD to meet its corporate goals and for Takeda to have future commercial products.
POSITION ACCOUNTABILITIES:<ul><li>
Clinical Development team participation and leadership
<ul><li>Leads Global (US/EU/Japan/China) Development Team for a given product. May lead the Development Sub Teams or study teams and represents Clinical Science on the Global (US/EU/Japan) Development Team to ensure that activities are aligned with the global strategy.</li><li>
Establishes and drives Development Team strategy and deliverables producing the Development Strategy, Clinical Development Plan and Clinical Protocols. Recommends scope, complexity and size, and influence the budget of all aspects of a program. Provides continual critical evaluation of the development strategy to maintain a state-of-the-art development plan that is competitive and consistent with the latest regulatory requirements, proactive identification of challenges, and development of contingency plans to meet them.</li><li>
Responsible for high impact global decisions: monitoring and interpreting data from ongoing internal and external studies, assessing the medical and scientific implications, and making recommendations that impact regional and global development such as &ldquo;go/no go&rdquo; decisions or modification of development plans or study designs that may have a significant impact on timelines or product labeling. A significant error in judgment may result in loss of approvability and commercial viability of a product.</li></ul></li><li>
Synopsis / Protocol Development, Study Execution, &amp; Study Interpretation
<ul><li>Drives clinical science activities relating to the preparation / approval of synopses, protocols and the conduct of clinical studies. Serves as an advisor to other clinical scientists involved in these activities, and is accountable for the successful design and interpretation of clinical studies. Presents study conclusions to Management and determine how individual study results impact the overall compound strategy.</li><li>
Interprets data from an overall scientific standpoint as well as within the context of the medical significance to individual patients.</li></ul></li><li>
Trial Medical Monitoring
<ul><li>Responsible for medical monitoring activities, assessing issues related to protocol conduct and/or individual subject safety. Assesses overall safety information for studies and compound in conjunction with Pharmacovigilance. Oversees non-medical clinical scientists with respect to assessment of these issues.</li><li>
Makes final decisions regarding study conduct related to scientific integrity.</li></ul></li><li>
External Interactions
<ul><li>Directs activities involved in interactions with regulatory authorities / agencies and clinical development activities undertaken to establish and maintain strong relationships with key opinion leaders relevant to assigned compounds and therapeutic areas. These responsibilities include leadership roles in meetings with the regulatory organizations or key opinion leaders, establishment of strategy for assigned compounds, and the direction of clinical scientists involved in developing documents required to outline the Company positions on research programs or regulatory applications (e.g. briefing reports), materials used for meeting presentations, and formal responses to communications received from the regulatory organizations or opinion leaders. Lead roles will also be taken on the incorporation of advice / recommendations received into the design of clinical studies / programs as appropriate; accountable to senior leadership for the successful completion of related objectives.</li></ul></li><li>
Due Diligence, Business Development and Alliance Projects
<ul><li>Responsible for identification and evaluation of potential business development opportunities, conduct due diligence evaluations, and development and negotiation of clinical development plans for potential alliances and or in-licensing opportunities. Assesses scientific, medical, and development feasibility, evaluating strategic fit with overall portfolio, evaluating complete or ongoing clinical trials, assessing regulatory interactions and future development plans, interacting with upper management of potential partner/acquisition companies during DD visits and alliance negotiations, and representing clinical science on internal assessment teams in conjunction with GPLS &amp; Business Units.</li><li>
Serves as clinical contact point for ongoing alliance projects and interface with partner to achieve Takeda&rsquo;s strategic goals while striving to maintain good working relationship between Takeda and partner.</li></ul></li><li>
Leadership, Task Force Participation, Upper Management Accountability
<ul><li>Interacts directly with Neuroscience Drug Discovery Unit based on pertinent clinical and development expertise and with Business Units to provide knowledge / understanding of market environment in line with status as R&amp;D scientific content matter expert for assigned compounds. May represent clinical science on multidisciplinary task forces across divisions (e.g. R&amp;D; USBU; GPLS, JPBU). Lead R&amp;D internal teams and may lead global cross-functional teams, as appropriate.</li></ul></li></ul>
EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS:
<ul><li>MD or internationally recognized equivalent plus 5 years of clinical research experience within the pharmaceutical industry, CRO health-related consulting company, or biomedical/clinical experience within academia (or a combination of afore mentioned).</li><li>
Previous experience successfully leading a clinical development team/matrix team with responsibility for phase 3 clinical studies in multiple regions.</li><li>
NDA/MAA/Submission experience preferred.</li><li>
Management experience</li></ul>
Skills<ul><li>
Superior communication, strategic, interpersonal and negotiating skills</li><li>
Ability to proactively predict issues and solve problems</li><li>
Ability to drive decision-making within a multi-disciplinary, multi-regional, matrix teams</li><li>
Diplomacy and positive influencing abilities</li></ul>
Knowledge<ul><li>
Therapeutic area knowledge relevant to mechanism of action</li><li>
Expertise in psychiatry</li><li>
Regional/global Regulatory requirements</li><li>
GCP/ICH</li><li>
Emerging research in designated therapeutic area</li></ul>
TRAVEL REQUIREMENTS:
Ability to drive to or fly to various meetings or client sites, including overnight trips. Some international travel may be required.
Requires approximately &ndash;10 - 20% travel.
This position is currently classified as &ldquo; hybrid&rdquo; in accordance with Takeda&rsquo;s Hybrid and Remote Work policy.
Empowering Our People to Shine
Discover more at takedajobs.com
No Phone Calls or Recruiters Please.
#LI-JV2
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - MA - Cambridge
U.S. Base Salary Range:
$237,200.00 - $372,790.00 
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.<h2 class="jobSectionHeader">
Locations</h2>
USA - MA - Cambridge<h2 class="jobSectionHeader">
Worker Type</h2>
Employee<h2 class="jobSectionHeader">
Worker Sub-Type</h2>
Regular<h2 class="jobSectionHeader">
Time Type</h2>
Full time
Job Exempt
Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.</div>

Medical Director, Clinical Science, Neuroscience TAU- Psychiatry

<div>By clicking the &ldquo;Apply&rdquo; button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda&rsquo;s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.<h2 class="jobSectionHeader">
Job Description</h2>
Our Labs of Tomorrow vision is bold: We will deliver at least one groundbreaking medicine to patients every year by working &lsquo;smarter&rsquo; rather than &lsquo;harder&rsquo;. We are making this possible by improving our processes for agility, while increasingly integrating AI/ML and lab automation into our workflows.
Objective / Purpose:
We are seeking a Senior Director, Head of High-Throughput Screening (HTS), DNA-Encoded Libraries (DEL), and Sample Management to lead a strategic function supporting discovery across small and large molecule portfolios. This leader will be responsible for advancing screening and compound/sample management capabilities, driving innovation in hit identification, and ensuring operational excellence across highly automated platforms and large-scale libraries.
The ideal candidate brings deep scientific and operational expertise in HTS, DEL, and sample management, with a proven track record leading high-performing teams, shaping strategy, and influencing senior stakeholders across a matrixed R&amp;D organization.
Accountabilities:
Scientific and Technical Leadership<ul><li>
Lead and evolve enterprise capabilities in high-throughput screening, DEL screening, and sample management in support of discovery programs across therapeutic areas.</li><li>
Oversee screening strategies for small molecules, ensuring robust assay execution, hit identification, triage, and progression.</li><li>
Provide deep expertise in 1536-well screening, assay miniaturization, screening cascade design, and operational scale-up.</li><li>
Drive scientific excellence in HTS principles, screening statistics, assay performance metrics, and data quality assessment, including use of controls, normalization approaches, and hit-calling methodologies.</li><li>
Apply advanced knowledge of statistical analysis to support high-confidence decision-making across large and complex datasets.</li><li>
Champion integration of AI and computational approaches for hit selection, pattern recognition, data mining, and broader screening data analysis.</li><li>
Bring direct experience with DNA-Encoded Library (DEL) technologies, including screening strategy, data interpretation, and integration with complementary hit-finding platforms.</li></ul>
Sample Management and Operational Excellence<ul><li>
Lead end-to-end sample management operations for both small and large molecules.</li><li>
Oversee management of large compound and sample libraries exceeding 1 million samples, ensuring integrity, accessibility, traceability, and efficient deployment.</li><li>
Direct operation and continuous improvement of large integrated automated storage systems and associated workflows.</li><li>
Establish and maintain best practices in sample QC, inventory governance, plating, cherry-picking, reformatting, and shipment readiness.</li><li>
Drive reliability, quality, and scalability of operations through strong process discipline, metrics, automation, and continuous improvement.</li></ul>
Strategy and Cross-Functional Partnership<ul><li>
Develop and execute a forward-looking strategy for HTS, DEL, and sample management aligned with portfolio and platform priorities.</li><li>
Partner closely with medicinal chemistry, biology, data science, automation, informatics, and discovery leadership to deliver integrated hit discovery solutions.</li><li>
Communicate scientific strategy, operational performance, risks, and investment priorities effectively to senior leadership.</li><li>
Identify emerging technologies and external innovations that can enhance screening performance, speed, and decision quality.</li></ul>
People Leadership<ul><li>
Lead, inspire, and develop a large organization of scientists and operational staff.</li><li>
Build a high-performance, inclusive, and accountable team culture focused on scientific rigor, collaboration, and innovation.</li><li>
Coach leaders and team members, strengthen organizational capabilities, and ensure appropriate succession planning.</li><li>
Set clear goals, empower teams, and model outstanding people leadership.</li></ul>
Education &amp; Competencies (Technical and Behavioral):
<ul><li>PhD with 15+ years&rsquo; experience in chemistry, biology, pharmaceutical sciences, engineering, or related discipline with 15+ years&rsquo; experience, MS with 21+ years experinece, or BS with 23+ years&rsquo; experience</li><li>
Significant industry experience in high-throughput screening, sample management, and discovery operations, including leadership at senior level.</li><li>
Demonstrated hands-on and strategic expertise in HTS, including 1536-well platforms, assay execution, screening data analysis, and hit triage.</li><li>
Direct experience with compound/sample management for both small and large molecules.</li><li>
Experience managing libraries greater than 1 million samples.</li><li>
Experience operating and optimizing large integrated automated storage systems.</li><li>
Strong knowledge of sample quality control, inventory integrity, and operational best practices.</li><li>
Deep understanding of screening statistics, data quality metrics, and quantitative analysis methods.</li><li>
Experience applying or enabling AI/ML approaches for hit selection and screening data analysis.</li><li>
Prior experience with DNA-Encoded Libraries (DEL) strongly preferred, ideally with direct operational and scientific leadership responsibility.</li><li>
Proven success leading large teams of 20+ scientists, including managers and technical experts.</li><li>
Exceptional communication, influencing, and stakeholder management skills, including experience presenting to senior executives.</li><li>
Strong strategic mindset with demonstrated ability to build capabilities and deliver organizational impact.</li><li>
Strategic and future-oriented thinker</li><li>
Outstanding people leader and talent developer</li><li>
Strong operator with a focus on excellence and continuous improvement</li><li>
Collaborative and influential across functions and levels</li><li>
Scientifically rigorous, data-driven, and innovation-minded</li><li>
Clear, confident communicator with executive presence</li></ul>
ADDITIONAL INFORMATION
The position will be based in Cambridge, MA. This position is currently classified as &ldquo;hybrid&rdquo; by Takeda&rsquo;s Hybrid and Remote Work policy.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MA
U.S. Base Salary Range:
$212,000.00 - $333,190.00 
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.<h2 class="jobSectionHeader">
Locations</h2>
Boston, MA<h2 class="jobSectionHeader">
Worker Type</h2>
Employee<h2 class="jobSectionHeader">
Worker Sub-Type</h2>
Regular<h2 class="jobSectionHeader">
Time Type</h2>
Job Exempt
Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.</div>

Research Senior Scientific Director, Head of Hit ID and Sample Management (Automation)

Join Takeda Pharmaceuticals and explore 6   exciting career opportunities. They're hiring for various roles with options for remote or on-site work. Apply today and become part of their innovative team.