Assistant Professor in Biophysics of Living Systems

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Change: Combine physics and biology to decode cells at the nanoscale. Impact: New insights into disease and the fundamentals of life. Job description Imagine watching the inner workings of a living cell, where the fundamental laws of physics meet the complexity of life at the nanoscale. Since 2010, the Department of Bionanoscience at Delft University of Technology has been on a pioneering quest to decode these principles. We are a multidisciplinary and international community of scientists driven by a singular mission: to understand how interactions at the smallest scales give rise to biological function or the onset of disease. From observing the dance of single molecules to the bottom-up construction of synthetic cells, we bridge the gap between physics and the full complexity of living systems. Now, we invite you to join our group of 19 Principal Investigators at TU Delft to help us write the next chapter in our understanding of Life. The Department of Bionanoscience, part of the Kavli Institute of Nanoscience Delft, is a world-leading environment for fundamental research at the interface of biology and physics. We focus on biological processes from the level of single molecules to the full complexity of living cells. We seek an early career Principal Investigator who has demonstrated excellence in experimental research and thrives on conducting original research with impact, geared to understanding how life works, either at the molecular or cellular level. We encourage applications from researchers with a biophysics-oriented perspective or approach. Harnessing your communication skills, you inspire and convince funding agencies and partners of your vision and research. You actively seek collaboration with relevant faculties, universities and external stakeholders. In addition, you enjoy mentoring, teaching and interacting with students, while continuously developing yourself and your academic career. Your research will benefit from our in-house facilities, including a central optical microscopy, a cell culture, a protein purification, a cryo-EM, mass spectrometry, flowcytometry, and the Kavli Nanolab Delft cleanroom. Our laboratory space is located in a modern building with dedicated lab areas for building and operating sensitive physical instrumentation. As a Principal Investigator, you will: Establish an independent experimental research line that is complementary to our current strengths in single-molecule biophysics, synthetic biology, and quantitative cell biology. Secure external funding through competitive grants (e.g., NWO Vidi, ERC StG) to build and lead a team of PhD students, Postdocs and Technicians. Provide excellent education by teaching and developing courses for our unique BSc and MSc programs in Nanobiology; a program at the interface of biology, physics and math. Contribute to a collaborative culture, interacting synergistically with existing research groups and participating in the management of the department and our educational program(s). Job requirements The ideal candidate is a creative experimentalist who thrives on scientific and engineering challenges. You should possess: A PhD in a relevant field (e.g., Biophysics, Biochemistry, Cell biology, Bionanotechnology) and relevant post-doctoral experience. An outstanding scientific track record, evidenced by high-quality publications. A clear vision for a new, independent experimental research line that uses advanced methodology to probe, manipulate or engineer cellular life or its components. A passion for education and the ability to inspire students in an international environment. Obtain the University Teaching Qualification (UTQ) within three years. TU Delft (Delft University of Technology) Working at TU Delft means contributing to solutions that really make a difference. For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow. These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future. At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional. Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward. Faculty Applied Sciences With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers. about this vacancy or the selection procedure, please contact Martin Depken, Chair Department Bionanoscience, via or S.M.Depken@tudelft.nl. Application procedure Are you interested in this vacancy? Please apply no later than 30 July 2026 upload the following documents: Motivation letter (max 2 pages). Detailed CV and a full publication record. Research plan outlining your vision for an experimental program in the physics of life (max. 3 pages). Teaching statement describing your educational philosophy and ambitions (max. 1 page). We encourage you to apply as soon as possible, as we will begin contacting applicants while the vacancy is still open. Due to the summer break, interviews are scheduled to take place in September. You can address your application to Martin Depken, Chair Department Bionanoscience. Please note: You can apply online. We will not process applications sent by email and/or post. As part of knowledge security, TU Delft conducts a risk assessment during the recruitment of personnel. We do this, among other things, to prevent the unwanted transfer of sensitive knowledge and technology. The assessment is based on information provided by the candidates themselves, such as their motivation letter and CV, and takes place at the final stages of the selection process. When the outcome of the assessment is negative, the candidate will be informed. The processing of personal data in the context of the risk assessment is carried out on the legal basis of the GDPR: performing a public task in the public interest. You can find more information about this assessment on our website about knowledge security. Please do not contact us for unsolicited services.
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