Description
Job Description
The project focuses on the generation, processing, and interpretation of high‑throughput omics datasets to understand molecular mechanisms underlying biological phenotypes. This includes integration of genomics, transcriptomics, proteomics, and/or metabolomics data to identify biomarkers, regulatory pathways, and functional networks. The research aims to support hypothesis‑driven discovery as well as data‑driven modeling using computational and statistical approaches.
Responsibilities
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Perform data preprocessing and quality control for omics datasets (e.g., FASTQ QC, adapter trimming, alignment, quantification).
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Conduct bioinformatics analyses such as differential expression, pathway enrichment, clustering, and network analysis.
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Use established pipelines and tools.
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Maintain and update data management systems, ensuring proper documentation, version control, and reproducibility.
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Assist with sample preparation protocols when needed (RNA extraction, library prep, protein isolation, mass‑spec sample prep).
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Generate figures, reports, and visualizations for internal meetings, manuscripts, and presentations.
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Collaborate with senior researchers to interpret results and refine analytical strategies.
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Follow laboratory safety procedures and institutional guidelines.
Goals/Outcomes Of The Research Project
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Produce high‑quality, reproducible omics analyses that advance the project’s scientific aims.
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Identify key molecular signatures, pathways, or biomarkers relevant to the biological question.
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Contribute to manuscripts, presentations, and grant applications through data analysis and visualization.
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Develop and refine computational pipelines that can be reused by the research team.
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Support the generation of new hypotheses and experimental directions based on data‑driven insights.
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Build a robust, well‑documented dataset and analysis framework that supports long‑term research continuity.
Qualifications
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Bachelors or Masters degree in science or related field required
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No experience required. One year of research experience preferred.
Preferred Skills
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Bachelor?s or Master?s degree in Bioinformatics, Computational Biology, Molecular Biology, Genetics, Biostatistics, or a related field.
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Foundational understanding of molecular biology and high?throughput sequencing technologies.
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Proficiency in R and/or Python for data analysis.
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Familiarity with Linux/Unix environments.
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Strong organizational skills and ability to maintain detailed laboratory and computational records.
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Ability to work independently while contributing to a collaborative research environment.
Experience Preferred
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Prior experience with omics datasets (bulk or sc-RNA?seq, whole?genome sequencing, ATAC seq or ChiP-seq, proteomics, or metabolomics).
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Hands?on experience with at least one major analysis pipeline (e.g., differential expression, variant calling, clustering).
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Experience generating publication?quality plots and figures.
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Experience with machine learning, cloud computing, or workflow automation.
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Experience with wet?lab protocols relevant to sample preparation.
Employer Description
Strength through Unity and Inclusion
The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.
At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.
About The Mount Sinai Health System
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
Equal Opportunity Employer
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.
Compensation
The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58661 - $77125.98 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.