Clinical Research Principal Investigator

Job Summary
We are seeking a highly motivated and experienced Psychiatric Clinical Research Principal Investigator to lead and oversee industry sponsored clinical trials.

The PI will provide medical oversight, safety monitoring, and protocol leadership for psychiatric clinical trials involving investigational medications and treatments.

This role is designed to integrate efficiently into an established research infrastructure with experienced clinical research coordinators, regulatory support, and recruitment staff, allowing the PI to focus primarily on medical decision-making, participant safety, and protocol execution.. Your expertise will ensure that all research activities comply with regulatory standards, including FDA regulations and ICH Good Clinical Practice (GCP), while fostering collaboration across multidisciplinary teams. This position offers an exciting opportunity to contribute to cutting-edge medical research that has the potential to transform patient care worldwide.

Responsibilities

• Lead the planning, initiation, and execution of clinical trials in accordance with study protocols, regulatory requirements, and ethical standards.
• Participant Safety & Medical Oversight

Investigator Responsibilities

• Attend investigator meetings and sponsor calls as required.
• Screening evaluations
• Psychiatric diagnostic assessments
• Eligibility confirmations
• Review medical history, medications, and laboratory results.
• Monitor for adverse events and serious adverse events (SAEs).
• Provide clinical oversight of study participants throughout the trial.
• Attend investigator meetings and sponsor calls as required.
• Maintain oversight of: Delegation of authority logs, Safety reporting, Protocol compliance
• Collaborate with research coordinators on clinical decision-making.

Clinical Assessments

Depending on the study, responsibilities may include:

• Psychiatric diagnostic confirmation
• Clinical Global Impression (CGI)
• Safety and tolerability evaluations
• Medication management related to protocol requirements
• Oversight of clinician-rated scales when required

Team Collaboration

• Work closely with:
• Clinical Research Coordinators
• Research Assistants
• Regulatory staff
• Study sponsors and CROs
• Provide medical guidance to the research team regarding participant safety and protocol adherence.

Requirements

• Proven track record leading clinical trials or clinical research projects within regulated environments compliant with FDA regulations and ICH GCP standards.
• Valid ICH GCP certificate from a recognized issuer for CA or equivalent certification demonstrating knowledge of clinical trial conduct.
• Familiarity with patient monitoring procedures within clinical studies; understanding of HIPAA compliance is essential.
• Strong documentation review skills ensuring accuracy in regulatory submissions and study reports.
• Excellent organizational skills with the ability to manage multiple projects simultaneously while maintaining attention to detail.
• Effective communication skills for collaborating across multidisciplinary teams including clinicians, laboratory scientists, regulatory personnel, and external partners. Join us in advancing innovative medical solutions through rigorous scientific research! This paid position offers an engaging environment where your expertise will directly impact the future of healthcare while supporting your professional growth in a dynamic field dedicated to improving lives worldwide.
• Qualifications Required: MD or DO degree; Active California medical license
• Board Certified or Board Eligible in Psychiatry; Current DEA registration

Preferred:

• Previous experience as:
• Principal Investigator
• Sub-Investigator
• or clinician in industry-sponsored clinical trials

Final compensation is determined based on:

• prior research experience
• PI vs Sub-Investigator background
• board certification
• therapeutic area expertise

Additional compensation may include:

• Investigator meeting honoraria
• Publication participation
• Performance-based research stipends where permitted by study budgets.

Research Focus Areas

The site conducts trials in areas including:

• Major Depressive Disorder
• Bipolar Depression
• Anxiety Disorders
• PTSD
• Substance Use Disorders
• Cognitive impairment and neuropsychiatric conditions

Studies may include investigational medications, neuromodulation therapies, and novel psychiatric treatments.

Pay: $210.00 - $230.00 per hour

License/Certification:

• California Physician License (Required)

Ability to Commute:

• Chino, CA 91710 (Required)

Willingness to travel:

• 25% (Required)

Work Location: In person