Head of IT

Overview

The Head of IT is responsible for building, scaling, and securing the company’s enterprise IT and infrastructure foundation. This includes enterprise systems architecture, cloud platforms, identity & access management, endpoint lifecycle management, SaaS governance, and security/compliance programs. This role combines strategic leadership with hands-on execution to build and scale secure, reliable, and cost-efficient infrastructure. As the most senior IT leader, you’ll set direction, establish best practices, and partner cross-functionally to support company growth.

This is a high-impact opportunity to build and evolve a modern, hybrid infrastructure spanning cloud and on-premises environments in a collaborative, fast-growing setting.

Responsibilities

• Infrastructure Strategy & Architecture: Define and execute the infrastructure roadmap, designing scalable, resilient systems that support growth and high availability.

• Cloud & Automation (AWS): Lead cloud architecture and operations with a focus on performance, security, and cost optimization. Drive Infrastructure-as-Code and automation to improve efficiency and scalability.
• Security, Identity & Compliance: Oversee identity and access management, SSO, and security standards. Support compliance efforts, including IT general controls and audit readiness.

• Reliability & Operations: Establish monitoring, incident response, and disaster recovery practices to ensure system reliability and business continuity, and all day-to-day IT Operations and support.
  

• SaaS & Vendor Management: Manage SaaS ecosystem and vendor relationships, optimizing tools, usage, and spend.
• Endpoint & IT Operations: Oversee device lifecycle management, endpoint security, and MSP partnerships.
  

Minimum Requirements

• 8-10+ years of experience in IT, infrastructure, or systems engineering
• 3–5+ years in a leadership or senior-level role (e.g., Manager, Lead, or Director)
• Bachelor’s degree or master’s in computer science, Information Technology, Computer engineering or a related field (preferred)
• Hands-on experience designing and operating cloud infrastructure (AWS preferred), including networking, scalability, high availability, and disaster recovery
• Experience with identity and access management (IAM/SSO) and security best practices
• Familiarity with compliance frameworks (e.g., ITGCs/SOX), including access, change management, and audit controls
• Experience managing SaaS environments, vendors, and licensing optimization
• Working knowledge of monitoring, alerting, and incident response practices
• Exposure to Infrastructure-as-Code (e.g., Terraform), automation, and version-controlled environments
• Proven ability to partner cross-functionally and manage competing priorities in a fast-paced environment
• Strong communication skills, with the ability to translate technical concepts for business stakeholders

Nice to Have

• Experience supporting data-intensive or scientific computing environments
• Experience in biotech, pharma, or other regulated industries
Experience scaling infrastructure in a high-growth company

What we offer:

• Industry-competitive compensation
• Annual target bonus
• Stock options
• 401K plan
• Career advancement opportunities
• Monthly town halls to share business and scientific updates

Work Hard, Stay Well

• Comprehensive medical, dental, and vision plans for employees and their dependents
• Health and Dependent Care FSA and HSA Plan with a monthly Neomorph contribution
• Employee Assistance Program
• 10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
• Supplemental pay for Pregnancy Disability Leave
• Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care

Lifestyle

• Casual work environment
• Volunteer days off each year to spend time contributing to causes you care about
• Flexible work schedule
• Access to onsite gym
• On-site space to store your bicycle (or surfboard)

Have Fun!

We believe in work/life balance, and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (e.g., Padres games, summer picnic, holiday party, bring-your-kids-to-work day).

About Us:

Neomorph is a venture-backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets’. Our team is comprised of industry-leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment.

Neomorph is headquartered in San Diego, California.

Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state, or local law.