Laboratory Manager | Laboratory of Host-Pathogen Biology

Organization Overview: Our lab has developed novel CRISPR-based tools for functional genomics in the globally important pathogen, Mycobacterium tuberculosis. At Rockefeller, you will join a dynamic research team to investigate the mechanisms that enable this bacterium to cause disease and evade current antibiotics, with the long-term goal of developing new strategies to improve control of this pandemic. Overview: Responsibilities:

Oversee and advance research on the biology of Mycobacteria, focusing on functional genomics, antibiotic resistance, and host–pathogen interactions. This role integrates experimental design, laboratory compliance, and grant administration. As a part of scientific research team, conduct CRISPRi-based genetic perturbation experiments and functional genomics studies to investigate mycobacterial biology; perform molecular cloning, PCR, gene expression analysis, DNA/RNA isolation, deep sequencing, and metabolomics; develop and optimize new experimental protocols and standard operating procedures (SOPs); analyze and interpret data, contributing to publications in peer-reviewed scientific journals. Handle daily operations of a research laboratory. Handle project management, including managing expenditures and ensuring compliance with funding agencies; preparing financial justifications and grant compliance documentation for institutional and sponsor requirements; and coordinating multi-disciplinary teams in preparing and submitting research grant proposals.

Qualifications:

Degree: Master’s in Microbiology or a closely related field (or a foreign degree equivalent)

Experience: 2 years of experience with management and coordination of multi-institutional, internationally funded tuberculosis research projects (grant compliance, progress reporting, and laboratory team coordination).

Skills:

Proficiency in tuberculosis molecular microbiology and genetic analysis; ability to conduct research in high-containment biosafety level-3 (BSL-3) laboratory; skills with molecular assay development for antibiotic-resistance studies, and microbiological and analytical techniques (DNA and RNA extraction, quantitative PCR, electrophoresis, protein analysis, and flow cytometry); ability to develop and optimize laboratory-based diagnostic and experimental assays for tuberculosis research.

Compensation Range: Min: USD $107,000.00/Yr. Compensation Range: Max: USD $110,000.00/Yr.