Research Assistant

About the role

The Di Giovanni laboratory investigates the molecular signalling and transcriptional mechanisms that control axonal sprouting and regeneration. Given that neurological recovery and axonal regeneration are not possible following a spinal injury, understanding how the re-growth of injured axons is controlled is key to enhancing axonal regeneration and potentially functional recovery. Axonal signalling and metabolic control seem important for modulating the complex gene expression program necessary for the regrowth of an axon. However, the role of environmental factors in signalling and metabolic pathways in axonal regeneration remains obscure.

You would be working on a grant from AMRF which aims to manipulate metabolism and glycobiology to repair after spinal cord injury. We believe this will facilitate the wound healing process as well as axonal growth and synaptic plasticity, with the goal to foster functional recovery after spinal cord ]injuries.

What you would be doing

You will carry out research programmes in molecular and cellular underpinnings of regenerative failure after spinal cord injuries with focus on metabolism and glycobiology with the goal to identify novel targets for repair. You will be expected to generate data of high quality that can be submitted for publication to high-profile refereed journals and to attract external research funding.

Whilst conducting data analysis, you will always ensure the validity and reliability of data, maintain accurate and complete records, producing reports for research sponsors. Data will be presented to both colleagues, and at conferences, promoting the reputation of the group, the department and college. Developing key contacts and research collaborations both within the wider community and within the college are essential.

What we are looking for

• You should hold a Masters degree (or equivalent) in psychology, biomedical science, biomedical engineering, or neuroimaging
• You should have practical experience within a research environment and using techniques related to neurobiology, metabolism and glycobiology. Experience with in vivo research is desirable, but not essential. It is essential that you can work independently and collaboratively. You should have knowledge of gene expression analysis and practical experience working in a busy laboratory.

What we can offer you

• The opportunity to continue your career at a world-leading institution
• Sector-leading salary and remuneration package (including 38 days off a year)

Further information

This is a full-time, fixed term post until 30 September 2027 based at our Hammersmith Campus.

Should you require any further details on the role please contact Professor Simone Di Giovanni (s.di-giovanni@imperial.ac.uk).

Available documents