cell biology scientist

Broad Institute

<div><div><div><div><h3 class="jobSectionHeader"><b>General information
</b></h3></div></div><div><div><div><div>Location
</div><div>Burlington, MA
</div></div><div><div>Ref #
</div><div>43219
</div></div><div><div>Job Family
</div><div>Research
</div></div><div><div>Workplace
</div><div>On-Site
</div></div><div><div>Date published
</div><div>11/10/2025
</div></div><div><div>Time Type
</div><div>Full time
</div></div><div><div>Pay Range
</div><div>115,000 - 161,667 Usd Annual
</div></div></div></div></div><div><div><div><h3 class="jobSectionHeader"><b>Description &amp; Requirements
</b></h3></div></div><div><div><div><div><p>The Broad Institute&rsquo;s Genomics Platform seeks a collaborative, versatile Senior Scientist and Laboratory Lead for its cell engineering efforts. This role involves driving cutting-edge research and development in cellular technologies, specializing in cell culture, differentiation, and gene editing techniques. Working in an exciting and fast-paced environment, the Lead will design, execute, and manage complex cell engineering projects for both internal and strategic academic and commercial partners. You will be instrumental in defining and optimizing laboratory protocols, leading a small team of researchers and scientists, and ensuring the successful execution and delivery of highly technical projects. This exceptional opportunity offers the chance to work at the forefront of new cellular and molecular technologies and applications, directly contributing to high-impact biological research.<br>
<br>
</p><div>Responsibilities include developing a deep technical understanding of cell engineering applications and scientific project needs, establishing and maintaining strong relationships with cross-functional scientific and operational stakeholders, and managing all technical aspects of laboratory operations. This ranges from project design and protocol optimization to ensuring that experiments are executed to the highest standards, on time, and within budget. The ideal candidate will hold a strong, hands-on understanding of cellular and molecular biology technologies and applications, including mammalian cell culture, iPSC differentiation, high-throughput screening, and gene editing methodologies (e.g., CRISPR). You must be comfortable designing, executing, and troubleshooting complex scientific protocols, be systems-savvy, detail-oriented, and able to work independently to anticipate the needs of the research and stakeholders. The Lead will join a core technical team engaging with scientists within and external to the organization to explore and facilitate cutting-edge functional cell and genomics projects.<br>
<br>
<b>Characteristic Duties</b></div><ul><li> Serves as the primary technical lead for assigned cell engineering projects, designing experimental plans, setting performance metrics, and generating technical reports and data analysis.</li><li> Liaises with key scientific stakeholders to understand project goals, inform the development and optimization of technical protocols, champion cross-functional collaboration, and drive the implementation of research programs in alignment with scientific objectives.</li><li> Manages and supports laboratory collaborations with a focus on scientific rigor, consensus-building, and ensuring successful technical outcomes for a range of stakeholders; facilitates the creation of comprehensive project plans which include scientific scope, technical goals, resource requirements, roles and responsibilities, and technical risk analysis.</li><li> May lead a small team of scientists and research associates, providing mentorship, technical guidance, and ensuring efficient lab operation, including equipment maintenance and reagent inventory.</li><li> Works with internal and external stakeholders to proactively plan for future projects, including establishing timelines, resource requirements, and logistical/scientific requirements.</li><li> Designs and executes complex cell engineering experiments, including the culture, maintenance, and differentiation of various cell types, applying gene editing tools, and integrating with high-throughput screening and sequencing workflows.</li><li> Ensures all laboratory projects and activities adhere to institutional guidelines with regards to safety, regulatory compliance, and ethical standards.</li><li> Proactively anticipates, identifies, and mitigates potential technical issues during project execution; documents all experimental details and results accurately.</li><li> Develops and maintains a strong understanding of emerging cell, genomics, and related services and scientific needs; seeks opportunities to improve technical capabilities and grow the platform's scientific impact.</li></ul><div></div><div><b>
Experience and Requirements</b></div><ul><li> PhD in Cell Biology, Molecular Biology, Genetics, Bioengineering, or a related scientific discipline with 2+ years of relevant postdoctoral or industry experience; OR Master's with 7+ years of related experience.</li><li> Strong, hands-on familiarity with cell and molecular biology technologies (including mammalian cell culture, iPSC differentiation, gene editing, and sequencing workflows) and their applications is required.</li><li> Demonstrated ability to design, lead, and execute complex scientific projects with interdisciplinary teams to effectively manage and deliver on program goals.</li><li> Ability to adapt plans and priorities to rapidly shifting scientific goals and troubleshoot technical challenges creatively.</li><li> Able to handle a variety of tasks and effectively solve problems as they arise.</li><li> A high level of initiative and the ability to work independently, as well as in a team environment.</li><li> Highly detail-oriented with exceptional record-keeping and data analysis skills.</li><li> Excellent written and verbal communication skills; the ability to effectively communicate complex scientific information to diverse audiences.</li><li> Excellent time management, interpersonal, and organizational skills.</li></ul>
</div></div><div><div><div>The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.</div><div>
</div><div>
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.</div><div></div><div><br>
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.</div><div></div><div><br>
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.</div></div></div></div></div></div></div><div></div>

Senior Scientist, Cell Engineering Laboratory Lead

Thermo Fisher Scientific

<div><p><b>Work Schedule</b></p>
Standard (Mon-Fri)<p></p><p><b>
Environmental Conditions</b></p>
Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cold Room/Freezers -22degreesF/-6degrees C, Fluctuating Temps hot/cold, Laboratory Setting, Loud Noises (Equipment/Machinery), Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.), Will work with hazardous/toxic materials<p></p><p><b>
Job Description</b></p><p></p><p><b>
Job Title: Scientist I, Molecular Biology</b></p><p><b>
Job Location: India, Bangalore</b></p><p><b>
About Company:</b></p><p><b>
About the company</b></p><p><b>
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies &amp; Services makes it easier for customers.</b></p><p><b>
About Team: Antibody team</b></p><p><b>
The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is product development and creation of product specific information to promote research use.</b></p><h2 class="jobSectionHeader"><b>
Role &amp; Responsibilities
</b></h2><p><b>Role:</b></p><p><b>
To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular biology methods.</b></p><h2 class="jobSectionHeader"><b>
Responsibilities:</b></h2><ul><li>
Meticulous experimental planning and execution to meet program goals.</li><li>
Timely record keeping of results into data sheets and laboratory note-books.</li><li>
Regular mining of literature and keeping oneself up to date with developments in field of antibody development.</li><li>
Compilation and presentation of data in written and oral formats. Active participation in team meetings.</li><li>
Attention to detail and adherence to schedules.</li></ul><h2 class="jobSectionHeader"><b>
Candidate Requirement:</b></h2><p><b>
Education &amp; Experience levels:</b></p><p>
Applicants should have Master&rsquo;s with 0-3 years confirmed experience or a fresh PhD (submitted within last one year) in a life sciences field with a strong focus on protein design, protein purification, molecular biology, immunology, biotechnology or biochemistry.</p><h2 class="jobSectionHeader"><b>
Nature of experience:
</b></h2><ul><li>Experience in molecular biology, which could include nucleic acid extraction, PCR, and cloning. Experience working with RNA and understanding of best practices for RNA work.</li><li>
Experience with bioinformatics such as BLAST, pairwise and multiple sequence analysis, design and construction of expression vectors, codon optimization, PCR primer design. Experience with molecular biology software such as Snapgene, CLC Workbench or Geneious.</li><li>
Prior work in single cell molecular biology workflows, next generation sequencing and/or display technologies desirable.</li><li>
Knowledge and experience in protein purification, immunoassays such as ELISA, Western Blotting, Immunocytochemistry, Immunohistochemistry or Flow cytometry, and cell culture techniques. Experience with protein or antibody conjugation will be a plus.</li><li>
Theoretical or practical experience in antibody development platforms is desirable.</li><li>
Project or work experience in support of relevant skills such as publications, project reports or thesis work.</li><li>
Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.</li></ul><p>
The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate with the ability to work with different colleagues.</p><p>
Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates</p><p>
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!</p></div><p></p>

Scientist I, Molecular Biology

<div><p><b>Work Schedule</b></p>
Standard (Mon-Fri)<p></p><p><b>
Environmental Conditions</b></p>
Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cold Room/Freezers -22degreesF/-6degrees C, Fluctuating Temps hot/cold, Laboratory Setting, Loud Noises (Equipment/Machinery), Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.), Will work with hazardous/toxic materials<p></p><p><b>
Job Description</b></p><p></p><p><b>
Job Title: Scientist III, Molecular Biology</b></p><p><b>
Job Location: India, Bangalore</b></p><h2 class="jobSectionHeader"><b>
About Company:</b></h2><p><b>
About the company</b></p><p>
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies &amp; Services makes it easier for customers.</p><h2 class="jobSectionHeader"><b>
About Team: Antibody team</b></h2><p>
The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using pioneering tools and technologies. The goal of the program is advanced product development and creation of product specific information to promote research use.</p><h2 class="jobSectionHeader"><b>
Role &amp; Responsibilities</b></h2><h2 class="jobSectionHeader"><b>
To be a member in the molecular biology and sequencing core facility within an antibody development team through the advancement of innovative molecular biology techniques to enable high throughput recombinant antibody platforms.</b></h2><h2 class="jobSectionHeader"><b>
Responsibilities:</b></h2><ul><li>
Perform in a fast- paced environment towards antibody development &amp; testing</li><li>
Lead molecular biology and core facility to develop next generation methodologies, vector improvements, cloning strategies to facilitate high throughput workflows in recombinant antibody development platforms</li><li>
Informal leadership of team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists in research, design and experimental execution, interpreting data and data presentation to collaborators and partners.</li><li>
Drive conceptualization within teams to enable development of successful protocols for effective transfer to operation teams.</li><li>
Serve as authority in the field of molecular biology, sequencing, and antibody development to provide inputs and guidance towards driving innovation and cross team collaborations.</li><li>
Partner with supporting functions such as product management, program management, operations, and business development to meet program goals.</li></ul><p><b>
Candidate Requirement:</b></p><p><b>
Education &amp; Experience levels:</b></p><ul><li>
PhD with 4 to 5 years' experience, or</li><li>
Master&rsquo;s degree with 5 to 10 years' experience</li><li>
Min 3-4 years of Industrial experience is required</li></ul><p>
Applicants should have a degree in a relevant life sciences field with a strong focus on next generation molecular biology, sequencing technologies and antibody development technologies.</p><h2 class="jobSectionHeader"><b>
Nature of experience:</b></h2><ul><li>
Extensive experience with antibody development and engineering including hybridoma, display technologies, single B cell, and other antibody platforms</li><li>
Broad knowledge and experience in molecular biology, vector design, next generation cloning, miniaturizing strategies for high throughput gene to protein, Sanger and next generation sequencing technologies, antibody sequencing, protein and antibody design/engineering</li><li>
Excellent troubleshooting and problem-solving skills to identify and troubleshoot technical challenges and provide suitable solutions</li><li>
Consistent track record of establishing new protocols and workflows</li><li>
Experience leading core facilities for molecular biology and/or sequencing will be a plus</li><li>
Experience leading and mentoring people either with or without direct reporting structure</li><li>
Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging trends in the field are preferred.</li><li>
Flexibility and adaptability to work in a fast-paced research environment.</li><li>
Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.</li></ul><p>
The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate to varied colleagues.</p><p>
Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.</p><p>
We offer attractive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. We offer employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer a company culture that stands for integrity, intensity, involvement, and innovation!</p></div><p></p>

Scientist III, Molecular Biology

<div><p><b>Work Schedule</b></p>
Standard (Mon-Fri)<p></p><p><b>
Environmental Conditions</b></p>
Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cold Room/Freezers -22degreesF/-6degrees C, Fluctuating Temps hot/cold, Laboratory Setting, Loud Noises (Equipment/Machinery), Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.)<p></p><p><b>
Job Description</b></p><p></p><p><b>
Job Title: Scientist II, Protein Biology</b></p><p><b>
Job Location: India, Bangalore</b></p><p><b>
About Company:</b></p><p><b>
About the company</b></p><p><b>
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies &amp; Services makes it easier for customers.</b></p><p><b>
About Team: Antibody team</b></p><p><b>
The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is product development and creation of product specific information to promote research use.</b></p><p><b>
Role &amp; Responsibilities</b></p><p><b>
To be a member in the molecular biology and sequencing core facility within an antibody development team through the advancement of innovative molecular biology techniques to enable high throughput recombinant antibody platforms.</b></p><p><b>
Responsibilities:</b></p><ul><li> <b>Perform in a fast- paced environment towards antibody development &amp; testing</b></li><li> <b>Develop next generation methodologies, vector improvements, cloning strategies to facilitate high throughput workflows in recombinant antibody development platforms</b></li><li> <b>Informal leadership of team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists in research, design and experimental execution, interpreting data and data presentation to collaborators and partners.</b></li><li> <b>Drive conceptualization within teams to enable development of successful protocols for effective transfer to operation teams.</b></li><li> <b>Provide inputs and guidance towards driving innovation and cross team collaborations.</b></li><li> <b>Partner with supporting functions such as product management, program management, operations, and business development to meet program goals.</b></li></ul><p><b>
Candidate Requirement:</b></p><p><b>
Education &amp; Experience levels:</b></p><ul><li> <b>PhD with up to 3 years experience, or</b></li><li> <b>Master&rsquo;s degree with up to 8 years experience</b></li></ul><p><b>
Applicants should have a degree in a relevant life sciences field with a strong focus on next generation molecular biology, sequencing technologies and antibody development technologies.</b></p><p><b>
Nature of experience:</b></p><ul><li> <b>Experience with antibody development and engineering including hybridoma, display technologies, single B cell, and other antibody platforms</b></li><li> <b>Broad knowledge and experience in molecular biology, vector design, next generation cloning, miniaturizing strategies for high throughput gene to protein, Sanger and next generation sequencing technologies, antibody sequencing, protein and antibody design/engineering</b></li><li> <b>Excellent troubleshooting and problem-solving skills to identify and troubleshoot technical challenges and provide suitable solutions</b></li><li> <b>Experience in high throughput methods including automation is desirable</b></li><li> <b>Experience in establishing new protocols and workflows is desirable</b></li><li> <b>Experience leading core facilities for molecular biology and/or sequencing will be a plus</b></li><li> <b>Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging trends in the field are preferred.</b></li><li> <b>Flexibility and adaptability to work in a fast-paced research environment.</b></li><li> <b>Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.</b></li></ul><p><b>
The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate.</b></p><p><b>
Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.</b></p><p><b>
We offer attractive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. We offer employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer a company culture that stands for integrity, intensity, involvement, and innovation!</b></p></div><p></p>

Scientist II, Molecular Biology

GC Therapeutics

<div>
 <p>
  <strong>
   Scientist / Senior Scientist &ndash; Cell Line Development
  </strong>
 </p>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Company Overview
  </strong>
 </p>
 <p>
  GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell di&fflig;erentiation technology platform TFome&trade; was developed in Professor George Church&rsquo;s lab, a pioneerin synthetic biology,and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency, and speed. GC Therapeutics is basedin Cambridge, MA. For additional information, please visitwww.gc-tx.com.
 </p>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Job Purpose
  </strong>
 </p>
 <p>
  GC Therapeutics is seeking a highly motivated Scientist or Senior Scientist to join our Cell Line Development (CLD) team. This role focuses on iPSC scale-up and differentiation from benchtop to production-scale bioreactors. The ideal candidate will engineer novel cell therapy products derived from human induced pluripotent stem cells (iPSCs) for regenerative and cell-based therapies and will contribute to the development of cell line candidates for early-phase clinical trials as part of a team developing iPSC derived cellular products and related quality control assays.
 </p>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Duties and Responsibilities
  </strong>
 </p>
 <ul>
  <li>
   Culture iPSC lines including maintenance and analysis (e.g. cell culture, preparation of media, passaging, cryopreservation)
  </li>
  <li>
   Perform cell engineering on iPSCs to generate products for cell therapies.
  </li>
  <li>
   Design and execute experiments to optimize cell engineering processes for iPSCs and iPSC-derived cells .
  </li>
  <li>
   Perform, analyze and interpret experimental data, ensuring comprehensive documentation of methodologies and outcomes.
  </li>
  <li>
   Maintain a detailed laboratory journal, summarize results, and create presentations for meetings
  </li>
  <li>
   Troubleshoot iPSC cell line engineering challenges, improving process robustness for GMP readiness.
  </li>
  <li>
   Implement process changes for GMP compliance and support technology transfer to process development team.
  </li>
  <li>
   Contribute to the development of product characterization assays (e.g., identity, purity, potency, mechanism of action and functional assays).
  </li>
  <li>
   Draft and review batch records, SOPs and regulatory support documents for cell line engineering processes.
  </li>
  <li>
   Maintain accurate and complete records, ensuring compliance with documentation management systems.
  </li>
  <li>
   Collaborate with a multidisciplinary team including Analytical Development, Quality Assurance, Manufacturing, Operations, R&amp;D, etc.
  </li>
 </ul>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Qualifications
  </strong>
 </p>
 <p>
  <strong>
   <em>
    Essential Qualifications:
   </em>
  </strong>
 </p>
 <ul>
  <li>
   Advanced degree in cell biology, biochemical or biomedical engineering, cell therapy, or a related field with 2+ years of industry experience.
  </li>
  <li>
   Strong expertise in iPSC culture and maintenance, cell engineering, characterization of engineered cells, and cloning
  </li>
  <li>
   Hands-on experience with various cell type differentiation, characterization and experimental in-process and endpoint analysis including flow cytometry, ELISA and microscopy
  </li>
  <li>
   Significant experience with molecular biology tools for integration site and off-target analysis.
  </li>
  <li>
   Analyze differentiated cell products and establish QC metrics.
  </li>
  <li>
   Optimize, refine and scale differentiation protocols for candidate cell therapeutic products.
  </li>
  <li>
   Experience with documentation management systems
  </li>
  <li>
   Experience with working in the Controlled Non-classified Space.
  </li>
  <li>
   Knowledge of iPSC 2D and 3D cultures.
  </li>
  <li>
   Proficiency in quality management system and data analysis tools.
  </li>
  <li>
   Strong problem-solving, analytical, and documentation skills.
  </li>
  <li>
   Ability to work independently and collaboratively in a cross-functional team.
  </li>
  <li>
   Willingness to work outside normal hours including weekends to support lab activities as needed.
  </li>
 </ul>
 <p>
  <br/>
 </p>
 <p>
  <em>
   Additional Preferred Qualifications:
  </em>
 </p>
 <ul>
  <li>
   Experience with operations in GMP facilities and GMP guidelines.
  </li>
  <li>
   Experience in scale-up, process development using 3D culture, organoids and bioreactor systems.
  </li>
  <li>
   Proven track record and strong publications in stem cell or developmental biology.
  </li>
  <li>
   Knowledge of FlowJo, next generation sequencing (NGS), bioinformatics (R, Python).
  </li>
  <li>
   Expertise in genome integrity assessment and off-target characterization.
  </li>
  <li>
   Familiarity with automation, high throughput (HTP) imaging and cell cloning.
  </li>
  <li>
   Familiarity with relevant guidelines from the FDA, EMA and ICH.
  </li>
 </ul>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Experimental Techniques:
  </strong>
 </p>
 <p>
  <em>
   Cellular Biology:
  </em>
 </p>
 <ul>
  <li>
   Design and execute synthetic biology-based differentiation of iPSCs.
  </li>
  <li>
   Optimize, and scale iPSC derived differentiation for therapeutic cell products.
  </li>
  <li>
   Perform assays including Flow Cytometry, ELISA, ICC, cell-based assays and microscopy.
  </li>
  <li>
   Conduct DOE studies to optimize parameters affecting engineered iPSC growth and differentiation.
  </li>
 </ul>
 <p>
  <em>
   Molecular Biology:
  </em>
 </p>
 <ul>
  <li>
   Perform PCR, qPCR and ddPCR for cell characterization.
  </li>
  <li>
   Characterize target cells using next-generation sequencing (e.g., library preparation for bulk and single cell RNA-seq)
  </li>
  <li>
   Conduct genome integrity assessment and off-target characterization
  </li>
 </ul>
 <p>
  <em>
   General Laboratory:
  </em>
 </p>
 <ul>
  <li>
   Lead experimental design, data analysis, and presentation of results to team members.
  </li>
  <li>
   Maintain detailed and well-organized records of all experimental activities.
  </li>
  <li>
   Provide scientific and technical guidance to junior staff or contract manufacturing organizations (CMOs).
  </li>
  <li>
   Ensure compliance with GDP, GMP, safety regulations, and company policies.
  </li>
  <li>
   Stay current on scientific advancements and contribute to innovative research.
  </li>
 </ul>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Pay Range
  </strong>
 </p>
 <p>
  $120,000 - $145,000
 </p>
 <p>
  (This range reflects the base salary only and does not include additional compensation such as annual bonus and equity awards, which are part of the total compensation package.)
 </p>
 <p>
  <br/>
 </p>
 <p>
  Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
 </p>
 <p>
  <br/>
 </p>
 <p>
  At GC Therapeutics, our generous competitive benefits package also include generous PTO, paid holidays, Medical, Dental, Vision, 401(k), Life and Disability Insurance and transportation subsidy.
 </p>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Equal Opportunity Workplace:
  </strong>
  GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics&rsquo; equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.
 </p>
</div>


Scientist/Senior Scientist - Cell Line Development

<div><p><b>Work Schedule</b></p>
Standard (Mon-Fri)<p></p><p><b>
Environmental Conditions</b></p>
Laboratory Setting, Office<p></p><p><b>
Job Description</b></p><p></p><h2 class="jobSectionHeader"><b>
About Company:</b></h2><p></p><p>
We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory efficiency.</p><p></p><p>
Through our world-class brands &ndash; Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, and Unity Lab Services &ndash; we offer an unmatched combination of innovative technologies, purchasing convenience, and comprehensive services.</p><p></p><h2 class="jobSectionHeader"><b>
About Team:</b></h2><p></p><p>
Candidate will be working as part of Thermo Fisher Scientific Research and Development in the core cell culture module. The team caters towards strengthening the company&rsquo;s portfolio by supplying all the biological samples to develop and validate recombinant antibodies. We develop knockout cell models to validate and prove specificity of antibodies.</p><p></p><h2 class="jobSectionHeader"><b>
Role &amp; Responsibilities</b></h2><p></p><p>
Purpose:</p><p></p><p>
Thermo Fisher Scientific is looking for a Scientist who can foster innovation and improve customer results by crafting and validating cell culture procedures, materials, and supplies.</p><p></p><h2 class="jobSectionHeader"><b>
Responsibilities:</b></h2><p></p><ul><li>
Perform cell culture activities and laboratory techniques including aseptic expansion of immortalized cell lines, handling of primary cells and immortal cells</li><li>
Work with stem cells and perform different types of differentiations</li><li>
Conduct transfections and transductions</li><li>
Regular inspection of cell culture samples, including microscopy, gene expression assessment, Western blot/ELISA, and other applicable examinations</li><li>
Initiate, plan, and complete scientific research with emphasis on cell culture techniques independently</li><li>
Prepare customer-facing documents, including scientific writing and publication-quality images and figures</li><li>
Retain comprehensive records of cell culture parameters and results in data sheets and/or electronic notebooks</li><li>
Responsible for data integrity, accuracy, and analysis</li><li>
Deliver high-quality results according to project schedules in support of current and/or new products</li></ul><p></p><h2 class="jobSectionHeader"><b>
Skills and Experience</b></h2><p></p><ul><li>
Experimental skills with attention to detail are critical</li><li>
Transfection and transduction experience</li><li>
Demonstrated skill in collaborating within teams and guiding junior scientists</li><li>
Strong understanding and hands-on expertise with the culture of multiple mammalian cell types. The ideal candidate will have additional experience with protein biology, molecular biology, or other related subject areas</li><li>
Experience in primary and/or stem cell work is required</li><li>
Demonstrated skill in developing publication-quality documents. Candidates should showcase experience in publishing in peer-reviewed journals.</li><li>
Outstanding interpersonal skills</li><li>
Should be a strong teammate, eager to learn new techniques and creatively solve problems</li></ul><p></p><h2 class="jobSectionHeader"><b>
Candidate Requirement:</b></h2><p></p><p>
Education &amp; Experience levels:</p><p></p><ul><li>
Ph.D. degree in life sciences or Master&rsquo;s degree in Cell Biology/Biotechnology or a related Life Science field with 5-6 years of research experience</li><li>
Candidates must possess a solid foundation in Cell Biology</li></ul><p></p><h2 class="jobSectionHeader"><b>
Nature of experience:</b></h2><p></p><ul><li>
Should possess a solid grasp of the fundamentals of cell biology, cell physiology, and tissue development</li><li>
Should be capable of thinking, working independently, and carrying out experiments</li></ul><p></p><p>
At Thermo Fisher Scientific, every one of our 70,000 outstanding individuals has a distinctive story to share. Apply today!</p><p><b>
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.</b></p></div><p></p>

Scientist II

ALLEN INSTITUTE

<div><p><b><i>Scientist I &ndash; Human Cell Types - Alzheimer's Disease</i></b></p>
<p>The <b>mission</b> of the <b>Allen</b><b> </b><b>Institute</b> is to understand the principles that govern life, and to advance health. Our creative and multi-dimensional teams focus on answering some of the biggest questions in bioscience. We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world. The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through the integration of experiments, modeling, and theory.
</p><p>The <b>Seattle Alzheimer&rsquo;s Disease Brain Cell Atlas</b> (SEA-AD) consortium strives to achieve a deep molecular and cellular understanding of the early pathogenesis of Alzheimer&rsquo;s disease (AD). Leveraging advances in quantitative neuropathology and next-generation single cell molecular profiling technologies we are generating large-scale data sets from well-characterized donors that span the spectrum of AD pathology to comprehensively map human brain cell types across aging and disease. These data along with tools for their use are made freely and publicly available. We are seeking a highly motivated Scientist to contribute to this effort by designing and executing experiments at the interface of neuroanatomy, single-cell genomics, and histology. The Scientist will generate precisely dissected, high-quality human brain tissue samples, optimize and validate molecular and single-cell assays, and execute experiments (e.g., in situ hybridization, immunostaining) to validate computational findings. Working closely with experts in neuropathology, spatial transcriptomics, and computational analysis, the Scientist will help advance high-resolution molecular atlases of the human brain in health and disease. The ideal candidate will have a strong foundation in molecular neuroscience, experience with single-cell transcriptomic and/or epigenomic assays, and a working knowledge of Alzheimer&rsquo;s disease biology. Familiarity with human neuroanatomy and enthusiasm to deepen anatomical expertise are also essential.</p>
<p>At the Allen Institute, we believe that science is for everyone &ndash; and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.
</p><p>We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.
</p><p>We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.</p>
<p><b>Essential Functions</b></p>
<ul><li>Contribute to the design and execution of large-scale single-cell genomics experiments
</li><li>Participate in the development and testing of new single-cell methods and protocols</li>
<li>Optimize protocols for challenging samples, troubleshoot workflows for variable tissue quality, and evaluate tissue and sequencing library quality using standard metrics
</li><li>Conduct basic analysis of single-cell genomics data, including benchmarking of new methods
</li><li>Design and execute experiments to validate and extend computational results and generate novel biological insights</li>
<li>Present progress in group meetings and at scientific conferences, and contribute to peer-reviewed publications</li>
<li>Assist in management of tissue acquisition and sample tracking
</li><li>Maintain meticulous experimental records to ensure reproducibility across tissue donors and adherence to best practices for tissue handling, biosafety, and data integrity</li>
<li>Actively contribute to a collaborative environment focused on scientific rigor and methodological innovation</li>
</ul>
<p><i>*Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management&rsquo;s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.*</i></p>
<p><b>Required Education and Experience</b></p>
<ul><li>PhD degree in Neuroscience, Molecular Biology, Genomics, or related field, or equivalent combination of degree and experience</li>
<li>Demonstrated experience conducting independent experimental research and interpreting complex biological data</li>
<li>Broad knowledge of and experience with single-cell genomics platforms</li>
</ul>
<p><b>Preferred Education and Experience</b></p>
<ul><li>Proficiency in independently conducting single-cell genomics assays</li>
<li>Hands-on experience with human postmortem or surgical brain tissue, including dissection, nuclei isolation, and nucleic acid extraction
</li><li>Proven ability to troubleshoot complex molecular biology protocols and optimize workflows for variable sample quality</li>
<li>Basic experience or familiarity with multicolor flow cytometry</li>
<li>Basic familiarity with human neuroanatomy and willingness to expand anatomical knowledge</li>
<li>Proficiency in tissue sectioning, histological stains, and/or immunofluorescence panel optimization
</li><li>Ability to capture and analyze high-quality images using confocal or fluorescence microscopy and to quantify results with ImageJ/Fiji, QuPath, or similar applications</li>
<li>Experience with Python and/or R for basic data analysis and visualization and an understanding of core single-cell data analysis concepts (e.g., QC, clustering, marker identification)</li>
<li>Working knowledge of AD pathology and molecular mechanisms of disease</li>
<li>Excellent communication skills and comfort working in large, multidisciplinary teams to pursue collaborative research goals
</li><li>Strong quantitative and organizational skills, with attention to data quality and integrity</li>
</ul>
<p><b>Work Environment
</b></p><ul><li>Laboratory environment - possible chemical, biological, or other hazardous substances exposure
</li><li>Possible exposure to BioSafety Level 2 organisms, such as recombinant viruses</li>
<li>This may include wearing personnel protective equipment (PPE)</li>
<li>Working with dry ice or liquid nitrogen</li>
<li>Sample handling of the following material, including but not limited to: human brain tissues, non-human primate brain tissues, human whole blood, PBMCs, plasma, nucleic acids, and cells</li>
</ul>
<p><b>Physical Demands
</b></p><ul><li>Occasional lifting up to 30 pounds</li>
<li>Fine motor movements in fingers/hands to operate computers and other office equipment, repetitive motion with lab equipment</li>
<li>Stooping, bending, crouching
</li><li>Reaching or climbing ladders
</li></ul><p><b>Position Type/Expected Hours of Work</b></p>
<ul><li>This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with the flexibility to work remotely on a limited basis.
</li></ul><p><b>Additional Comments</b></p>
<ul><li>**Please note, this opportunity offers<b> </b>relocation assistance**</li>
<li>**Please note, this opportunity may offer work visa sponsorship**</li>
</ul>
<p><b>Annualized Salary Range</b></p>
<p>$86,150 - $106,650*</p>
<ul><li>Final salary depends on the required education for the role, experience, level of skills relevant to the role, and work location, where applicable.</li></ul>
<p><b>Benefits
</b></p><p>Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute&rsquo;s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute&rsquo;s 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institute&rsquo;s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.</p>
<p><i>It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities</i></p></div>

Scientist I - Alzheimer's Disease

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