drug discovery scientist

FullThrottle Labs Pvt Ltd

<p>Role Overview</p><p>The company is an AI-driven computational drug discovery platform integrating cheminformatics, structural biology, systems biology, machine learning, quantum computing, and scalable scientific workflows to accelerate the identification of novel therapeutics.</p><p>We are seeking Senior Computational Drug Discovery Scientists to design, implement, validate, and productionize core scientific workflows for both small molecule and target discovery programs. This role requires deep scientific expertise combined with platform-oriented systems thinking to translate research into production-grade pipelines.</p><p>Key Responsibilities</p><p>1. Small Molecule Drug Design Workflows (LBDD/SBDD)</p><p>- <br/>Lead and implement workflows for de novo design, virtual screening, molecular docking, molecular dynamics (MD) simulations, FEP, QSAR/QSPR, and pharmacophore modeling, leveraging open-source packages (AutoDock Vina, GROMACS, LAMMPS, deep-learning accelerated solvers).</p><p>- <br/>Design, validate, and productionize screening pipelines for hit identification, ADMET prediction, and lead optimization.</p><p>- <br/>Conduct Structure-Activity Relationship (SAR) analysis, chemical space exploration, and property optimization using computational methods.</p><p>- <br/>Establish standards for compound library curation and high-quality assay data standardization for model training.</p><p>2. Target and Systems Biology Discovery</p><p>- <br/>Drive novel target identification and validation using multi-omics data (genomics, proteomics, transcriptomics), network biology, and literature mining.</p><p>- <br/>Perform pathway analysis and deep disease biology interpretation to generate mechanism-level hypotheses for drug programs.</p><p>- <br/>Build scalable, production-ready workflows for biological data integration and quantitative target prioritization.</p><p>3. Platform Integration and ML/AI Application</p><p>- <br/>Design modular, reproducible computational chemistry and biology workflows.</p><p>- <br/>Collaborate with software teams to productionize and scale pipelines on cloud/HPC.</p><p>- <br/>Integrate deep learning models with model tracking, versioning, and deployment.</p><p>- <br/>Support development and/or integration of agentic workflows into platforms.</p><p>- <br/>Contribute to scientific documentation and intellectual property (IP) generation.</p><p>Required Technical Skills</p><p>- <br/>Strong expertise in at least one core area of computational drug discovery:</p><p>- <br/>Ligand-Based Drug Design (LBDD) and/or Structure-Based Drug Design (SBDD)</p><p>- <br/>Computational Structural Biology (MD, FEP, docking, with proficiency in tools like GROMACS, AMBER, NAMD, and Desmond)</p><p>- <br/>Computational Systems Biology / Target Discovery</p><p>- <br/>Hands-on experience with forcefield-based simulations.</p><p>- <br/>Direct exposure to implementing and utilizing deep learning in drug discovery, including generative models.</p><p>- <br/>Advanced proficiency in Python programming (RDKit, NumPy, PyTorch)</p><p>- <br/>Proven experience building and optimizing scalable computational scientific pipelines.</p><p>- <br/>Solid understanding of the end-to-end small molecule drug discovery decision process.</p><p>- <br/>Strong knowledge of best practices in benchmarking, reproducibility, and rigorous scientific validation.</p><p>Preferred Skills</p><p>- <br/>Track record of contributions to research publications, patent applications, or invention disclosures.</p><p>Educational Qualifications</p><p>- <br/>PhD in one of the following (mandatory):</p><p>- <br/>Computational Chemistry</p><p>- <br/>Cheminformatics</p><p>- <br/>Computational Biology</p><p>- <br/>Drug Discovery</p><p>- <br/>Systems Biology</p><p>- <br/>Related quantitative life sciences discipline</p><p>Experience Requirements</p><p>- <br/>2&ndash;5 years of relevant post-PhD experience in computational drug discovery/design and platform development or related fields.</p><p>- <br/>Demonstrated experience building end-to-end, high-throughput computational screening and analysis workflows.</p><p>- <br/>Experience working with complex, real-world biological and chemical datasets in a pharmaceutical or biotech context.</p><p>- <br/>Proven exposure to interdisciplinary collaboration.</p><p>Job Type: Full-time</p><p>Pay: ₹1,200,000.00 - ₹1,500,000.00 per year</p><p>Work Location: In person</p><p><b>Speak with the employer</b><br/>+91 9008078505</p>

Senior Computational Drug Discovery Scientist

Biogen

<div><p><b>Scientist, Machine Learning, Molecular Design
</b></p><p></p><p><b>About This Role
</b></p><p></p><p>The Computational Molecular Science team at Biogen is searching for a scientist interested in machine learning applications and transformative artificial intelligence algorithms to accelerate and improve the established small molecule design cycle that consists of idea generation, evaluation, and synthesis. This is a unique opportunity to join a cross-functional team working at the intersection of computational, chemical, and biological sciences and have direct access to a wealth of structured and unstructured data across the Biogen research organization to make a massive impact on redefining the early drug-discovery platform.
</p><p></p><p><b>What You&rsquo;ll Do
</b></p><p></p><ul><li>Build and deploy ML-driven molecular design workflows that combine deep generative models and deep reinforcement learning to propose and prioritize small molecules under multi-parameter objectives (potency, ADMET, novelty, synthesizability).
</li>Develop and maintain predictive models and molecular representations (e.g., GNNs/Transformers, 2D/3D features) and integrate them into iterative &ldquo;generate score<li> learn&rdquo; design loops.
</li><li>Collaborate with Computational Chemistry and cross-functional Drug Discovery teams to translate project needs into robust, reproducible tools and deliver measurable impact on small-molecule programs.
</li><li>Publish and present methodological and applied work internally and externally.
</li></ul><p></p><p>The successful candidate will be a creative and highly motivated scientist with demonstrated expertise in the field of machine learning and cheminformatics. You will be expected to stay current with the scientific literature and apply the latest advances in computational methods to address drug discovery challenges. As a key contributor to the molecule informatics group, thinking independently to solve complex problems is an important aspect of this position.
</p><p></p><p><b>Required Skills
</b></p><p></p><ul><li>Ph.D. in Computer Science (or related field) with strong fundamentals in machine learning, deep learning, and optimization.
</li><li>1+ years of postdoctoral experience with demonstrated ability to lead research projects independently and deliver high-quality results.
</li><li>Proven ability to work effectively in a multidisciplinary environment.
</li><li>Strong track record of publications and/or scientific presentations demonstrating impact and scientific rigor.
</li><li>Excellent oral and written communication skills, including the ability to explain technical work to both technical and non-technical audiences.
</li></ul><p></p><p><b>Preferred Skills
</b></p><ul><li>Strong hands-on experience developing and training deep learning models end-to-end (data pipelines, model design, training loops, debugging, and evaluation) using PyTorch or TensorFlow.
</li><li>Proven experience with modern deep generative models for molecular design (e.g., Transformer, GAN; diffusion/graph models are a plus)
</li><li>Experience applying deep reinforcement learning and/or multi-objective optimization to molecular generation and prioritization (e.g., reward design, constraint handling, Pareto trade-offs).
</li><li>Solid understanding of deep learning best practices (regularization, hyperparameter tuning, representation learning, uncertainty estimation, and generalization under data shift).
</li>Strong Python skills and practical experience with the ML ecosystem; cheminformatics experience is a plus.<br>
<li>
</li></ul><p></p><br>
Job Level: Professional<br>
<p><br>
<b>Additional Information
</b></p><p></p>The base compensation range for this role is: $117,000.00-$152,000.00<br>
<div><p><br>
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills &amp; experience, job location, and internal equity.
</p><p></p><p>Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
</p><p></p><p>In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees&rsquo; and their families <i>physical, financial, emotional, </i>and <i>social well-being </i>; including, but not limited to:
</p><ul><li>Medical, Dental, Vision, &amp; Life insurances
</li><li>Fitness &amp; Wellness programs including a fitness reimbursement
</li><li>Short- and Long-Term Disability insurance
</li><li>A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
</li><li>Up to 12 company paid holidays + 3 paid days off for Personal Significance
</li><li>80 hours of sick time per calendar year
</li><li>Paid Maternity and Parental Leave benefit
</li><li>401(k) program participation with company matched contributions
</li><li>Employee stock purchase plan
</li><li>Tuition reimbursement of up to $10,000 per calendar year
</li><li>Employee Resource Groups participation
</li></ul></div><p></p><div><p><b>Why Biogen?
</b></p><p>We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
</p><p></p><p>At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&amp;I efforts.
</p><p></p><p>All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.</p></div></div>

Scientist, Machine Learning, Molecular Design

University of Arizona

<div></div><div><div><div><div><div><b>Posting Number</b></div> <div>req25261
</div></div><br>
<div><div><b>Department</b></div> <div>Pharmacology and Toxicology
</div></div><br>
<div><div><b>Department Website Link</b></div> <div>https://www.pharmacy.arizona.edu/departments-directory/pharmacology-toxicology-department</div>
</div><br>
<div><div><b>Medical Sub-Speciality</b></div>
</div><br>
<div></div><div><div><b>Location</b></div> <div>Tucson Campus
</div></div><br>
<div><div><b>Address</b></div> <div>Tucson, AZ USA
</div></div><br>
<div><div><b>Position Highlights</b></div>
<div><p>Plan, design, coordinate, and conduct projects and experiments in the areas of Alzheimer's disease and CNS research. Instruct, mentor, and supervise junior researchers and staff scientists working in this space. Develop, facilitate, implement, evaluate, perform, administer and oversee research programs and initiatives in this research space. Initiate and contribute to research papers and research grants in this research space.</p><p><i>
Outstanding U of A benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; U of A/ASU/NAU tuition reduction for the employee and qualified family members; retirement plans; access to U of A recreation and cultural activities; and more!</i>
</p><p>The University of Arizona has been recognized for our innovative work-life programs.</p></div><br>
</div><br>
<div><div><b>Duties &amp; Responsibilities</b></div>
<div><ul><li>Developing, planning, designing, coordinating, and conducting drug discovery projects in the CNS and ADRD research space.</li><li>
Writing grants as PI, MPI, and co-I, and/or collaborator.</li><li>
Mentoring, training and supervising junior researchers and postdoctoral scholars in drug discovery and neurobiology techniques, including bioassays and animal records.</li><li>
Developing, planning, prioritizing, and carrying out experiments to support neurobiology and drug discovery in CNS and ADRD targets.</li><li>
Writing papers as corresponding author co-author.</li></ul>
</div></div><br>
<div><div><b>Minimum Qualifications</b></div>
<div><ul><li>PhD in Biochemistry or related field.</li><li>
Postdoctoral research experience.</li></ul>
</div></div><br>
<div><div><b>Preferred Qualifications</b></div>
</div><br>
<div></div><div><div><b>Rank </b></div><div>Assistant Professor
</div></div><br>
<div><div><b>Tenure Information</b></div> <div>Career-Track (CT)</div>
</div><br>
<div><div><b>FLSA</b></div> <div>Exempt
</div></div><br>
<div><div><b>Full Time/Part Time</b></div> <div>Full Time</div>
</div><br>
<div><div><b>Number of Hours Worked per Week</b></div> <div>40
</div></div><br>
<div><div><b>Job FTE</b></div> <div>1.0</div>
</div><br>
<div><div><b>Work Calendar</b></div> <div>Fiscal</div>
</div><br>
<div><div><b>Job Category</b></div> <div>Faculty</div>
</div><br>
<div><div><b>Benefits Eligible</b></div> <div>Yes - Full Benefits
</div></div><br>
<div><div><b>Rate of Pay</b></div> <div>DOE salary commensurate with AACP/AAMC public school benchmarks</div>
</div><br>
<div><div><b>Compensation Type</b></div> <div>salary at 1.0 full-time equivalency (FTE)
</div></div><br>
<div><div><b>Type of criminal background check required:</b></div> <div>Name-based criminal background check (non-security sensitive)
</div></div><br>
<div><div><b>Number of Vacancies</b></div> <div>1
</div></div><br>
<div><div><b>Target Hire Date</b></div>
</div><br>
<div></div><div><div><b>Expected End Date</b></div>
</div><br>
<div></div><div><div><b>Contact Information for Candidates</b></div> <div>Gregory Thatcher | GThatcher@pharmacy.arizona.edu
</div></div><br>
<div><div><b>Open Date</b></div> <div>2/23/2026</div>
</div><br>
<div><div><b>Open Until Filled</b></div> <div>Yes</div>
</div><br>
<div><div><b>Documents Needed to Apply</b></div> <div>Curriculum Vitae (CV) and Cover Letter</div>
</div><br>
<div><div><b>Special Instructions to Applicant</b></div>
</div><br>
<div></div><div><div><b>Notice of Availability of the Annual Security and Fire Safety Report</b></div> <div>In compliance with the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act (Clery Act), each year the University of Arizona releases an Annual Security Report (ASR) for each of the University&rsquo;s campuses. These reports disclose information including Clery crime statistics for the previous three calendar years and policies, procedures, and programs the University uses to keep students and employees safe, including how to report crimes or other emergencies and resources for crime victims. As a campus with residential housing facilities, the Main Campus ASR also includes a combined Annual Fire Safety report with information on fire statistics and fire safety systems, policies, and procedures.
<br>
Paper copies of the Reports can be obtained by contacting the University Compliance Office at cleryact@arizona.edu.</div></div></div></div></div>

Assistant Research Professor

Neomorph, Inc.

<div><p><b>Position summary:</b></p>
<p>
We are seeking a highly motivated medicinal chemist with excellent leadership skills, strong in strategic thinking and experienced with working in multi-disciplinary teams (spanning chemistry, biology, analytical sciences, pharmacology, DMPK and toxicology). The successful candidate will lead projects from inception to clinical candidate nomination, advancing our targeted protein degradation (TPD) platform. Applicants should be experienced drug hunters with a track record of innovation and creative problem solving. The candidate will also manage collaborations and CRO resources as needed.<br>
</p><p></p><br>
<p><b>Role and responsibilities:</b></p>
<ul>
<li>Responsible for the success of chemistry aspects of a drug discovery team through individual contributions, and through mentorship of junior colleagues[DP1]</li>
<li>Can independently lead a Lead Optimization project and manage the chemistry team to advance towards candidate selection in collaboration with other line functions
</li><li>Leading from the bench- candidate will spend a portion of their time in the lab, enabling and impacting from the bench
</li><li>Accountable for providing guidance, direction and contributing to project delivery through the development of people
</li><li>Manage external chemistry CROs and work with external partners to profile compounds
</li><li>Work within mandated laboratory safety policies and practices and maintain an electronic notebook to company standards
</li>Contribute to patent filings, publications and presentations<br>
<li>
</li></ul><p></p><br>
<p><b>Required qualifications:</b>
</p><ul><li>Ph.D. in organic chemistry with 6+ years, MS with 9+ years or BS with 12+ years of relevant experience
</li><li>High level of creativity and productivity with strong synthetic problem-solving skills, synthetic methods and reactions mechanisms are required
</li><li>Demonstrate expertise in drug design and medicinal chemistry strategies to improve drug-likeness, ADME/DMPK and safety properties
</li><li>The candidate should have experience in both structure based and ligand based drug design concepts
</li><li>The candidate should have experience working with external drug discovery CROs
</li><li>The candidate should have deep understanding of molecular properties and DMPK concepts
</li><li>Knowledge and experience in assessing and establishing intellectual property
</li><li>The candidate should have an established interest and passion for new modalities and targeted protein degradation
</li><li>Exceptional interpersonal skills</li><br>
</ul>
<p></p><p><b>Preferred qualifications:</b>
</p>Experience in targeted protein degradation as a therapeutic modality.<br>
<ul><li>
</li></ul><p></p><br>
<p><b>What we offer:</b></p>
<ul>
<li>Industry competitive compensation</li>
<li>Annual target bonus</li>
<li>Stock options</li>
<li>401K plan</li>
<li>Career advancement opportunities</li>
<li>Monthly town halls to share business and scientific updates</li></ul><br>
<p></p>
<p><b>
Work Hard, Stay Well</b></p>
<ul>
<li>Comprehensive medical, dental, and vision plans for employees and their dependents</li>
<li>Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution</li>
<li>Employee Assistance Program</li>
<li>10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.</li>
<li>Supplemental pay for Pregnancy Disability Leave</li>
<li>Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care</li></ul><br>
<p></p>
<p><b>
Lifestyle</b></p>
<ul>
<li>Casual work environment</li>
<li>Volunteer days off each year to spend time contributing to causes you care about</li>
<li>Flexible work schedule</li>
<li>Access to onsite gym</li>
<li>Onsite space to store your bicycle (or surfboard)</li></ul><br>
<p></p>
<p><b>
Have Fun!</b></p>
<p>
We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).</p><p><br>
</p><p><b>About Us:</b></p>
<p>
Neomorph is a venture backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against &lsquo;undruggable targets&rsquo;. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment.</p>
<p>
Neomorph is headquartered in San Diego, California.</p>
<p>
Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state or local law.</p><p></p><p><b><i><br>
Notice to agencies:</i></b><i> Neomorph will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Neomorph via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Neomorph. No fee will be paid in the event the candidate is hired by Neomorph as a result of the referral or through other means.</i></p></div>

Associate Principal Scientist, Medicinal Chemistry

Arrowhead Pharmaceuticals

<div>
 <p>
  Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead&rsquo;s RNAi-based therapeutics leverage this natural pathway of gene silencing.
 </p>
 <p>
  <br/>
 </p>
 <p>
  Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
 </p>
 <p>
  <br/>
 </p>
 <p>
  Arrowhead&rsquo;s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI &amp; San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
 </p>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   The Position
  </strong>
 </p>
 <p>
  <br/>
 </p>
 <p>
  Arrowhead Pharmaceuticals is seeking a highly motivated Senior Scientist I to join our Discovery Analytical Chemistry team. In this role, you will play a critical part in advancing our protein and protein conjugate therapeutics by developing and implementing advanced LC-MS analytical strategies that support discovery and early process development activities.
 </p>
 <p>
  This is an opportunity to contribute at a high scientific level - designing innovative analytical solutions, influencing drug discovery direction, and collaborating cross-functionally to solve complex research challenges. The successful candidate will bring deep technical expertise in protein characterization and quantitation, along with the ability to translate analytical findings into meaningful insights that drive program decisions.
 </p>
 <p>
  <br/>
 </p>
 <p>
  You will serve as both a scientific leader and hands-on contributor, independently developing and optimizing analytical methods while mentoring junior scientists and helping shape analytical strategy within the team.
 </p>
 <p>
  <br/>
 </p>
 <p>
  <em>
   Responsibilities
  </em>
 </p>
 <ul>
  <li>
   Develop project and technical strategy within area of expertise
  </li>
  <li>
   Apply advanced scientific principles, theories and concepts to a broad range of research problems and develop innovative solutions for analytical problems related to drug discovery and development
  </li>
  <li>
   Design and execute analytical studies to facilitate drug discovery and platform development in various disease areas
  </li>
  <li>
   Independently design and initiate development of analytical methods and improvement of existing ones
  </li>
  <li>
   Serve as a project coordinator for on-going and new analytical method development
  </li>
  <li>
   Work independently and collaboratively with teams to solve scientific /technical challenges
  </li>
  <li>
   Develop and validate analytical methods to quantify and characterize drugs and impurities
  </li>
  <li>
   Conduct sample analysis, analyze data/results, interpret the outcome of experiments and integrate scientific findings to gain further understanding of drug properties or synthetic/purification route
  </li>
  <li>
   Represent team to present research findings to cross-function teams
  </li>
  <li>
   Identify, propose and lead areas for initiatives /improvement
  </li>
  <li>
   Influence and support drug discovery/development directions with scientific findings
  </li>
  <li>
   Train and mentor junior scientists in the team
  </li>
  <li>
   Other duties as assigned
  </li>
 </ul>
 <p>
  <em>
  </em>
 </p>
 <p>
  <strong>
   Requirements
  </strong>
 </p>
 <ul>
  <li>
   PhD in analytical chemistry or close related fields with 2+ years relevant industry experience
  </li>
  <li>
   Strong hands-on experience of using LC-MS and HPLC for proteins/protein conjugates characterization and quantitation
  </li>
  <li>
   Expertise in sample preparation, peptide mapping, MS/MS peptide sequencing, glycosylation analysis, disulfide bond mapping, and post-translational modifications analysis
  </li>
  <li>
   In-depth understanding of protein chemistry and analytical chemistry
  </li>
  <li>
   Familiar with routine maintenance of mass spectrometers
  </li>
  <li>
   Strong troubleshooting and problem-solving skills
  </li>
  <li>
   Excellent ability for data interpretation and integration
  </li>
  <li>
   Excellent communication and presentation skills
  </li>
  <li>
   Ability and willingness to learn cutting edge technologies
  </li>
  <li>
   Ability to prioritize the workload and adapt to fast changes
  </li>
 </ul>
 <p>
  <br/>
 </p>
 <p>
  <strong>
   Preferred
  </strong>
 </p>
 <ul>
  <li>
   Open mind and willing to learn new technology
  </li>
  <li>
   Experience with a wide range of analytical techniques
  </li>
  <li>
   hands on experience with CE or MALS is a plus but not necessary
  </li>
 </ul>
 <p>
  <br/>
 </p>
 <p>
  Wisconsin pay range: $125,000 USD - $145,000 USD
 </p>
 <p>
  <br/>
 </p>
 <p>
  Arrowhead provides competitive salaries and an excellent benefit package.
 </p>
 <p>
  All applicants must have authorization to work in the US for a company.
 </p>
 <p>
  California Applicant Privacy Policy
 </p>
</div>


Sr Scientist I, Discovery Analytical Chemistry

Alkermes, Inc.

<div><p>The Neurobiology Group is seeking a skilled candidate to participate in an internship (8 &ndash; 12 weeks) to assist with our drug discovery and assay development efforts. The selected candidate will independently conduct lab-based behavioral neuroscience research utilizing in vivo rodent behavior models. The goal of this paid internship is to provide an entry-level scientist with the opportunity to learn and take part in drug discovery research.
</p><p>The intern will operate both autonomously and as part of a multi-disciplinary team to execute an independent project, gaining proficiency in advanced experimental methodologies and theoretical frameworks pertaining to CNS disorders. The project encompasses various facets of in vivo research, such as animal handling and dosing, necropsy, assay development and validation, as well as statistical analysis. Primary responsibilities include daily management and care of laboratory animals, routine execution of rodent behavioral assays, fundamental data management and visualization, acquisition of essential laboratory techniques, active participation in scientific discourse, and preparation of scientific presentations.</p></div>
<br><div><div><div><p><b>Why join Team Alkermes?
</b></p><p>Alkermes applies its decades of deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we seek to make a meaningful difference in the way people manage their diseases. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
</p><p></p><p>We are proud to have been recognized as an employer of choice by many national organizations. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts&rsquo; Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
</p></div><div><p>Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.</p></div></div></div>
<br>Degree LevelBachelor's Degree

Intern, Functional Neuroanatomy

Calico Life Sciences

<div>
 <strong>
  Who We Are
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 Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico&rsquo;s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
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  Position Description
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 Calico is seeking a highly motivated neuroscientist to join a collaborative research team focused on Parkinson&rsquo;s Disease biology. This is a position for a fearless scientist interested in testing emerging mechanistic and therapeutic hypotheses through the development of fit-for-purpose
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  in vivo
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 models. The candidate should have a broad background in systems neuroscience and neurophysiology. The candidate will work closely with scientists and leaders in translational neuroscience, research physiology, genomics, data science and advanced imaging groups. The candidate may lead programs from exploratory biology through early drug development.
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  Key Responsibilities
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   Design, execute and interpret in vivo experiments that may involve stereotactic surgeries, viral delivery, and pharmacology
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   Provide scientific leadership for projects involving CROs, external partners, and internal collaborations
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   Model creation, licensing, colony planning and maintenance, in coordination with Laboratory Animal Resources and relevant vendors
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  Position Requirements
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   PhD in biology, neuroscience or related discipline, and 5+ years of relevant post-doctoral or industry experience
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   Deep knowledge of neuroanatomy, brain sectioning, and clearing methods
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   Proficient in stereotactic surgery
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   Track record of linking molecular to functional changes, ideally in models of neurodegeneration and disease pathobiology
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   Experience with viral and genetic tools
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   Strong teamwork and proactive communication skills
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   Self-motivated and able to work independently in a cross-functional team environment
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   Proficiency with R, Python, or equivalent platform for data analysis and visualization
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   Meticulous with attention to detail
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   Must be willing to work onsite 5 days a week
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  </li>
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 The estimated base salary range for this role is $166,000 - $191,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.
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Senior Scientist, In Vivo Neuroscience

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