principal scientist

Bristol Myers Squibb

<div>Working with Us 
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. 
 
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . 
 
The Immunology and Cardiovascular Thematic Research Center (ICV TRC) at BMS is one of the fundamental Research units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS's internal invention engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities. 
 
Position Summary: 
 
We are seeking a translational scientist with a background in cardiovascular biology to identify and discover novel and existing biomarkers to support the progression of late-discovery programs to early phase clinical trials and beyond. As such, this position will involve a close collaboration with the development organization. The translational scientist may serve as a liaison of discovery to development. The successful candidate will collaborate closely with early discovery team members to drive the progression of programs, which may include assisting the completion of pharmacology studies and guide the selection and analysis of endpoints to support an early translational development plan, including patient segmentation hypotheses. They will be able to apply their knowledge of cardiovascular biology and translational aspects of cardiovascular medicine to establish pharmacodynamic endpoints consistent with mechanism of action, which may involve in vivo, functional-structural analyses and ex vivo or in vitro biochemical or molecular assays, including the development of novel assays. The position may work with human samples or human-relevant systems to test translational hypotheses identified in support of biomarker plan development. This is primarily an on-site, lab-based position but time in lab may be dependent on programmatic needs as discovery programs progress to development, to be determined in collaboration with the manager. 
 
Position Responsibilities:<ul><li>
Perform studies to define pharmacodynamic biomarkers of response and disease progression, as a member of a discovery team and can investigate and articulate how these biomarkers may translate to the clinic</li><li>
Thorough knowledge of experimental design, and a high level of technical laboratory skills (including cell culture of relevant cell lines and primary cells, immunoassays, such as ELISA/MSD, IHC, protein signaling, qPCR technology platforms) together with an ability to interpret results
</li><li>Employs technical knowledge and theory to make experimental in-life modifications, when necessary</li><li>
Lead studies to completion, including the hands-on analysis of samples internally or directing studies externally through management of CROs.
</li><li>Evaluate programs critically and present findings and recommendations to discovery teams and leadership</li><li>
Document, critically review, modify experimental approach, if necessary, and present experimental data in a timely manner.</li><li>
Collaborate with cross-functional teams by providing timely and actionable study results.</li><li>
Provide hands-on training and guidance to develop team members</li><li>
Contribute to and author reports, abstracts, and publications.</li></ul>
Experience =
 
 
Basic Qualifications:
<ul><li>Bachelor's Degree<ul><li>
8+ years of academic and / or industry experience</li></ul></li></ul>
Or<ul><li>
Master's Degree<ul><li>
6+ years of academic and / or industry experience</li></ul></li></ul>
Or<ul><li>
Ph.D. or equivalent advanced degree in the Life Sciences
<ul><li>4+ years of academic and / or industry experience</li></ul></li></ul>
Preferred Qualifications:<ul><li>
Ph.D. in Physiology, Pharmacology, Biology, Biochemistry, or a related field with 2+ years of relevant industry experience and 5+ years' experience after completion of terminal degree, including post-doctoral training. PharmD/DVM/MD may be considered with a strong track record of achievement in the basic sciences or drug discovery from hands-on contributions. Alternatively, an M.S. in a related field with 5+ years (after completion of degree) relevant industry experience.
</li><li>Strong understanding of cardiovascular physiology and modern cardiovascular methodologies (including those that may serve as pharmacodynamic endpoints) employed pre-clinically and clinically<ul><li>
Includes a strong understanding of imaging biomarkers used in the clinic (eg ultrasound-echocardiography, MRI, and PET)</li></ul></li><li>
An understanding of the considerations for the use of animals in research, with a focus species-specific use, and can articulate and apply 3Rs principles in designing and initiating experiments</li><li>
Hands-on experience handling rodents is necessary</li><li>
Expertise culturing and making biochemical and/or functional measurements in iPSC-CM, primary cardiac cells, and/or engineered heart tissues is necessary</li><li>
Excellent laboratory skills, prioritizing accurate and reproducible work.</li><li>
Skill in managing external collaborators and setting clear timelines and expectations</li><li>
Must be self-motivated, detail-oriented, collaborative, and able to work effectively in a multidisciplinary, matrixed team environment.</li></ul>
#LI-Onsite 
 
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
 
 
Compensation Overview: 
 
Princeton - NJ - US: $135,800 - $164,563
 
 
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.
 
 
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 
 
Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:
<ul><li>Health Coverage: Medical, pharmacy, dental, and vision care.</li><li>
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
</li><li>Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
</li></ul>Work-life benefits include:
 
 
Paid Time Off
<ul><li>US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
</li><li>Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
</li></ul>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
 
 
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. 
 
<ul><li>Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.
</li></ul> 
Uniquely Interesting Work, Life-changing Careers 
With a single vision as inspiring as Transforming patients' lives through science&trade; , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. 
 
On-site Protocol 
 
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
 
 
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
 
 
Supporting People with Disabilities 
 
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.
 
 
Candidate Rights 
 
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
 
 
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
 
 
Data Protection 
 
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection . 
 
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. 
 
If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.
 
 
R1600213 : Principal Scientist, Cardiovascular Translational Biomarker</div>

Principal Scientist, Cardiovascular Translational Biomarker

<div>Working with Us 
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. 
 
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . 
 
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
 
 
The Informatics and Predictive Sciences (IPS) mission is to Pioneer, Partner and Predict to drive transformative insights for patient benefit. IPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the field, both inside and outside the company.&quot; We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so, our work transforms the lives of patients, as well as our own lives and careers. 
 
Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. 
 
Summary 
 
We are seeking a highly motivated and innovative Principal computational scientist to lead efforts at the intersection of machine learning, agentic AI, and oncology target discovery. In this role, you will create and implement advanced algorithms and agent-based tools to analyze complex biological and clinical datasets to identify new therapeutic targets and deepen our understanding of resistance to standard care. In close partnership with cross-functional teams, you will integrate functional screens, diverse 'omics and real-world data to generate actionable insights. This role offers a unique opportunity to establish and scale cutting edge analytical capabilities that meaningfully accelerate oncology target discovery and improve patient outcomes. 
 
Key Responsibilities<ul><li>
Design, build, and deploy applied AI and agentic systems to automate and augment analytical workflows for target identification and validation using high-throughput omics, functional genomics, and perturbation screening data.</li><li>
Lead the integration of agentic and machine learning solutions into cross-functional research workflows in close collaboration with stakeholders.</li><li>
Integrate and analyze large-scale, patient-derived, multimodal datasets to elucidate disease biology, resistance mechanisms, and patient stratification opportunities.</li><li>
Translate complex analytical results into clear, actionable insights that inform scientific strategy and enable decision-making.</li><li>
Author scientific reports and present methods, results, and conclusions to a publishable standard.</li><li>
Contribute to the planning and execution of collaborative projects within and across functional groups.</li></ul>
Basic Qualifications
<ul><li>B achelor's Degree 8+ years of academic / industry experience
</li><li>or Master's Degree 6+ years of academic / industry experience
</li><li>or PhD 4+ years of academic / industry experience
</li></ul>Preferred Qualifications<ul><li>
Ph.D. in Computational Biology, Systems Biology, Computer Science, Machine Learning, Statistics, or a related quantitative field.</li></ul><ul><li>
Demonstrated experience developing and deploying applied AI agents and/or complex LLM-driven applications in research or industry settings.</li><li>
Strong understanding of analytical approaches for functional genomics, single-cell and spatial 'omics, and real-world patient data.</li><li>
Solid grounding in systems biology, molecular biology, and/or disease biology within a drug discovery context; experience in oncology is strongly preferred.</li><li>
Scientific Impact: Strong publication record in machine learning, bioinformatics, or computational biology, with the ability to clearly and effectively communicate scientific research to peers.</li><li>
Soft Skills: Excellent communication and collaboration skills, with the ability to operate effectively in ambiguous, fast-paced research environments and influence diverse stakeholders.</li></ul>
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
 
 
Compensation Overview: 
 
Cambridge Crossing: $166,770 - $202,086
 
 
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.
 
 
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 
 
Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:
<ul><li>Health Coverage: Medical, pharmacy, dental, and vision care.</li><li>
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
</li><li>Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
</li></ul>Work-life benefits include:
 
 
Paid Time Off
<ul><li>US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
</li><li>Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
</li></ul>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
 
 
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. 
 
<ul><li>Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.
</li></ul> 
Uniquely Interesting Work, Life-changing Careers 
With a single vision as inspiring as Transforming patients' lives through science&trade; , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. 
 
On-site Protocol 
 
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
 
 
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
 
 
Supporting People with Disabilities 
 
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.
 
 
Candidate Rights 
 
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
 
 
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
 
 
Data Protection 
 
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection . 
 
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. 
 
If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.
 
 
R1600329 : Principal Scientist, Oncology Informatics, AI agents</div>

Principal Scientist, Oncology Informatics, AI agents

<div>Working with Us 
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. 
 
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . 
 
The Cell Therapy Thematic Research Center is one of BMS's differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. 
 
Position Summary: 
 
We are seeking a highly skilled, collaborative, and detail-oriented scientist to join our Translational Research team, bringing deep expertise in CAR T cell therapy and a rigorous scientific foundation in immunology, molecular/cell biology, and/or virology. 
 
In this role, you will serve as a Translational Safety Strategy Lead, driving the evaluation of gene-modified CAR T cell product-related genotoxicity in alignment with established study protocols and applicable regulatory guidelines. Your work will span early- and late-stage clinical programs, with particular emphasis on post-marketing settings, ensuring robust and consistent translational safety oversight across a diverse CAR T portfolio. 
 
Position Responsibilities:<ul><li>
Lead end-to-end translational safety strategies, testing, and reporting across multiple assets and platforms, spanning clinical and commercial programs, ensuring critical alignment with research, clinical development, and medical affair objectives.</li><li>
Oversee complex testing operations, including sample testing workflows, case tracking, data flow, and data management operations; lead in-depth complex case investigations across clinical and commercial settings with scientific rigor and operational precision.</li><li>
Drive continuous process improvements, streamlining data reporting flows and optimizing testing workflows, assay services, and data reporting infrastructure; drive cross-functional efficiency through proactive operational dialogue and stakeholder engagement.</li><li>
Provide scientific leadership and interpretation, integrating translational safety data to inform critical clinical and regulatory decision-making; serve as a subject matter expert contributing scientific insights to health authority inquiries and regulatory submissions.</li><li>
Operate effectively in a fast-paced, highly matrixed environment , setting priorities with clarity, confidence, and adaptability , cultivating a collaborative and inclusive team culture, and building and sustaining strategic partnerships both internally and externally.</li></ul>
Basic Qualifications:
<ul><li>Bachelor's Degree<ul><li>
8+ years of academic and / or industry experience</li></ul></li></ul>
Or<ul><li>
Master's Degree<ul><li>
6+ years of academic and / or industry experience</li></ul></li></ul>
Or<ul><li>
Ph.D. or equivalent advanced degree in Life Sciences<ul><li>
4+ of academic and / or industry experience</li></ul></li></ul>
Preferred Qualifications:<ul><li>
Ph.D. with 7+ years of combined experience in clinical trial research and basic sciences, including industry and/or biotech settings, with strong background in cell therapy, immunology, molecular/cell biology, and/or virology.</li><li>
Exceptional scientific communication and writing skills, with demonstrated track record in manuscript writing and proven ability to collaborate effectively across cross-functional teams in a fast-paced, highly matrixed environment while managing completing priorities and tight timelines.</li><li>
Strong working knowledge of regulatory frameworks and requirements, including hands-on experience drafting and reviewing regulatory documents, supporting regulatory inquiries and submissions, and contributing to translational strategy development.</li></ul>
#LI-Onsite 
 
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
 
 
Compensation Overview: 
 
Seattle - WA: $152,360 - $184,628 
 
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.
 
 
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 
 
Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:
<ul><li>Health Coverage: Medical, pharmacy, dental, and vision care.</li><li>
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
</li><li>Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
</li></ul>Work-life benefits include:
 
 
Paid Time Off
<ul><li>US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
</li><li>Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
</li></ul>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
 
 
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. 
 
<ul><li>Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.
</li></ul> 
Uniquely Interesting Work, Life-changing Careers 
With a single vision as inspiring as Transforming patients' lives through science&trade; , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. 
 
On-site Protocol 
 
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
 
 
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
 
 
Supporting People with Disabilities 
 
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.
 
 
Candidate Rights 
 
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
 
 
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
 
 
Data Protection 
 
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection . 
 
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. 
 
If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.
 
 
R1600332 : Principal Scientist, Translational Research - Translational Safety Strategy</div>

Principal Scientist, Translational Research - Translational Safety Strategy

Flagship Pioneering, Inc.

<div>What if&hellip;

We could harness the power of Flagship's breakthrough scientific platforms to create entirely new therapeutic modalities &mdash; and deliver transformative medicines to patients faster?

Pioneering Medicines, a division of Flagship Pioneering, is building a premier biopharmaceutical R&amp;D organization dedicated to conceiving and advancing life-changing therapies. By integrating and applying Flagship's innovative platform technologies to serious diseases with high unmet need, we aim to redefine how medicines are discovered and developed. A defining strength of our approach is the ability to combine multiple platforms to generate truly novel and potentially transformative treatments.

About Flagship Pioneering

Flagship Pioneering is a life sciences innovation company that conceives, creates, resources, and develops first-in-category scientific ventures to transform human health and sustainability. Since its founding in 2000, Flagship has originated and fostered more than 100 scientific ventures, generating tens of billions in aggregate value and advancing breakthroughs across biotechnology and sustainability. Flagship's unique hypothesis-driven innovation model has enabled the creation and growth of an ecosystem of 40+ companies &mdash; including high-impact ventures such as Moderna, Tessera Therapeutics, Generate:Biomedicines, Sana Biotechnology, Indigo Agriculture, and Inari &mdash; that span cutting-edge platform technologies and therapeutic modalities

Position Summary:

We are seeking a Compound Manager at Senior Scientist/ Principal Scientist level to join our rapidly evolving Sample Operations and Automation function. This individual will collaborate with operational and scientific teams to manage the registration, storage, and distribution of small molecules, peptides, biologics and additional modalities, while leading the automation of liquid handling, serial dilutions, and assay plate dispensing workflows at Pioneering Medicines. In addition, the individual will collaborate with Information Technology to streamline data collection, analysis, and storage workflows.

The successful candidate will combine deep operational expertise with a hands-on approach to automation and process development, ensuring high-quality, reproducible data from early discovery programs across multiple therapeutic areas and modalities.

Key Responsibilities:

Compound and Sample Management
<ul>
<li>Oversee end-to-end compound management workflows through collaboration with the lab operations team, including receipt, registration, storage, tracking, and distribution of small molecules, peptides, biologics, nucleic acids, and other modalities across Pioneering Medicines' research programs.</li>
<li>Maintain sample integrity and traceability through robust documentation, inventory systems and adherence to SOPs.</li>
<li>Manage compound collections in proper storage systems (ambient, refrigerated, cryogenic), and ensure environmental compliance and monitoring, in collaboration with the laboratory operations group.</li>
</ul>
Automation and Workflow Execution
<ul>
<li>Partner with team members to operate, program, and maintain automated liquid handling systems (e.g., Agilent Bravo, Dispendix I.DOT) for high-throughput sample preparation.</li>
<li>Develop, validate, and optimize serial dilution, reformatting, and assay plate dispensing methods to enable high throughput assays and profiling campaigns.</li>
<li>Implement automation scheduling software (e.g., VWorks) to coordinate workflows and maximize throughput.</li>
<li>Drive continuous improvements in automation reliability and process standardization.</li>
</ul>
Data and Informatics Integration
<ul>
<li>Interface with informatics platforms (e.g., CDD Vault, Benchling, and compound databases) to ensure accurate data capture and seamless sample tracking.</li>
<li>Collaborate with data science teams to link sample metadata with experimental results for analytical and decision-support workflows.</li>
<li>Generate and maintain inventory, utilization, and QC reports across multiple program portfolios.</li>
</ul>
Qualifications:

Required:
<ul>
<li>Bachelor's or Master's degree in Chemistry, Biochemistry, Chemical Engineering, or related discipline with 12+ years of experience.</li>
<li>Strong experience in compound management within pharma, biotech, or high-throughput discovery environments.</li>
<li>Demonstrated proficiency with liquid handling platforms and compound inventory management systems.</li>
<li>Deep understanding storage considerations for diverse modalities (e.g., small molecules, peptides, biologics).</li>
<li>Proven ability to troubleshoot, optimize, and document automated workflows.</li>
<li>Strong organizational and communication skills, with the ability to manage multiple priorities in a dynamic environment.</li>
</ul>
Preferred:
<ul>
<li>Experience in multi-modal sample management (e.g., nucleic acids, conjugates).</li>
<li>Prior exposure to early-stage R&amp;D or platform company operations.</li>
</ul>
Core Competencies:
<ul>
<li>Operational excellence and meticulous attention to detail</li>
<li>Strong technical troubleshooting and analytical mindset</li>
<li>Collaborative and adaptable in a fast-evolving environment</li>
<li>Commitment to innovation, data integrity, and process improvement</li>
<li>Excellent written and interpersonal communication</li></ul> 


Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 


Recruitment &amp; Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, &quot;FSP&quot;) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

#LI-TD1<div>
The salary range for this role is $126,000 - $214,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Pioneering Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Medicines's good faith estimate as of the date of publication and may be modified in the future.</div></div>

Pioneering Medicines: Senior / Principal Scientist, Compound Management

<div>Working with Us 
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. 
 
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . 
 
Position Summary 
Translational Development is part of the Global Research organization in BMS and leads late-stage clinical, pharmacological and translational research and development activities for the pipeline and supports late-stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics.
 
 
Incumbents with deep training and education in cardiovascular, or related disease areas, including but not limited to neurocardiac research. 
 
Key Responsibilities:<ul><li>
Designs and implements program-specific development biomarker/translational plans</li><li>
Responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.</li><li>
Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable</li><li>
Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs</li><li>
Prepares and delivers internal and external translational/biomarker presentations</li><li>
Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed</li><li>
Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology</li><li>
Works with TM laboratory scientists and academic TLs to address nonclinical translational questions as needed</li><li>
Participates/leads post-hoc biomarker analysis and publication efforts</li><li>
Supports regulatory submissions and regulatory interactions as needed</li><li>
Participate in Diagnosis (PDx) biomarker assay development through collaboration with precision medicine group</li></ul>
Qualifications &amp; Experience:<ul><li>
PhD with 5-8+ years of translational medicine and clinical biomarker experience, including 5+ years supporting early- and/or late-stage clinical programs in biotech or pharma.</li><li>
Recognized expertise in translational biomarkers in cardiovascular or related disease areas, with experience in drug development and clinical trial initiation, conduct, and completion.</li><li>
Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables.</li><li>
Demonstrated scientific and project leadership experience, including working in cross-functional teams, mentoring, and managing projects, with the ability to identify risks and implement contingency plans.</li><li>
Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses.</li><li>
Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed; recognizes and communicates cross-functional issues across the organization.</li><li>
Ability to support multiple projects in a fast-paced, collaborative environment, with strong organizational skills, attention to detail, and accurate record keeping.</li></ul>
#LI-Hybrid 
 
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
 
 
Compensation Overview: 
 
Brisbane - CA - US: $184,060 - $223,036 
Cambridge Crossing: $184,060 - $223,036
 
Princeton - NJ - US: $160,060 - $193,949
 
 
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.
 
 
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 
 
Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:
<ul><li>Health Coverage: Medical, pharmacy, dental, and vision care.</li><li>
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
</li><li>Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
</li></ul>Work-life benefits include:
 
 
Paid Time Off
<ul><li>US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
</li><li>Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
</li></ul>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
 
 
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. 
 
<ul><li>Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.
</li></ul> 
Uniquely Interesting Work, Life-changing Careers 
With a single vision as inspiring as Transforming patients' lives through science&trade; , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. 
 
On-site Protocol 
 
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
 
 
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
 
 
Supporting People with Disabilities 
 
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.
 
 
Candidate Rights 
 
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
 
 
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
 
 
Data Protection 
 
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection . 
 
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. 
 
If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.
 
 
R1600104 : Senior Principal Scientist, Cardiovascular, Translational Development</div>

Senior Principal Scientist, Cardiovascular, Translational Development

Peraton

<div><div><h5 class="jobSectionHeader">ABOUT PERATON</h5>
Peraton is a next-generation national security company that drives missions of consequence spanning the globe and extending to the farthest reaches of the galaxy. As the world&rsquo;s leading mission capability integrator and transformative enterprise IT provider, we deliver trusted, highly differentiated solutions and technologies to protect our nation and allies. Peraton operates at the critical nexus between traditional and nontraditional threats across all domains: land, sea, space, air, and cyberspace. The company serves as a valued partner to essential government agencies and supports every branch of the U.S. armed forces. Each day, our employees solve the most daunting challenges that our customers face. Visit peraton.com to learn how we&rsquo;re keeping people around the world safe and secure.</div><div><h5 class="jobSectionHeader">
ABOUT THE ROLE</h5><div><div>
Peraton seeks a Principal Data Scientist to support Department of Defense Cyber Defense Command (DCDC) with DCO AI Cyber Security. Location: Fort Meade, MD. In this role, you will serve as technical lead for the Data Science Team, providing strategic direction for all advanced analytics, AI/ML, and predictive modeling initiatives supporting DCDC enterprise mission requirements.</div><div></div><div> 
Primary Responsibilities</div><ul><li>
Lead team of 6 data scientists, ML engineers, and operations research analysts</li><li>
Design and oversee AI/ML model development including NLP and network analysis</li><li>
Direct campaigns of learning and experimentation for analytic performance evaluation</li><li>
Develop predictive, prescriptive, and descriptive models for DCO-IDM operations</li><li>
Ensure analytics alignment with ASOM and Analytic Crosswalk framework</li><li>
Present analytic findings and recommendations to senior leadership</li></ul></div></div><div><h5 class="jobSectionHeader">
QUALIFICATIONS</h5><div><div>
Required Qualifications:</div><ul><li>
Minimum of 12 years with BS/BA; Minimum of 10 years with MS/MA; Minimum of 7 years with Ph.D.</li><li>
Expert proficiency in Python, R, and ML frameworks (TensorFlow, PyTorch, scikit-learn)</li><li>
Deep experience with NLP, network analysis, and time-series forecasting</li><li>
Strong background in statistical modeling and experimental design</li><li>
Experience with big data platforms (Hadoop, Spark)</li><li>
5+ years leading technical teams in DoD/IC environment</li><li>
U.S Citizenship required</li><li>
DoD TS with ability to obtain/maintain SCI clearance</li></ul><div>
 Preferred Qualifications:</div><ul><li>
AWS/Azure ML certifications are preferred</li><li>
CISSP certification is preferred</li><li>
Master's degree is required; PhD is preferred in Data Science, Statistics, Computer Science, or related field</li><li>
12 years of relevant experience</li></ul></div></div><div><h5 class="jobSectionHeader">
DETAILS</h5><div>
Target Salary Range: $146,000 - $234,000. This represents the typical salary range for this position. Salary is determined by various factors, including but not limited to, the scope and responsibilities of the position, the individual&rsquo;s experience, education, knowledge, skills, and competencies, as well as geographic location and business and contract considerations. Depending on the position, employees may be eligible for overtime, shift differential, and a discretionary bonus in addition to base pay.
</div><div>Benefits Statement: Peraton offers eligible employees a variety of benefits including medical, dental, vision, life, health savings account, short/long term disability, EAP, parental leave, 401(k), paid time off (PTO) for vacation, and company paid holidays. A full listing of available benefits can be viewed at https://www.careers.peraton.com/benefits.
</div><div>
Application Duration Statement: The application period for the job is estimated to be 30 days from the job posting date. However, this timeline may be shortened or extended depending on business needs and the availability of qualified candidates.
</div>
EEO: Equal opportunity employer, including disability and protected veterans, or other characteristics protected by law.</div></div><div></div>

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