senior bioinformatics scientist

Teacher of Arts (High school) Philosophy of the Arts (HKU)

<div>
 The University of Hong Kong
 
 
 Apply now
 
 Ref.:
 
 533322
 
 
 
 Work type:
 
 Full-time
 
 
 
 Department:
 
 Centre for PanorOmic Sciences (22200)
 
 
 
 Categories:
 
 Executive / Technical / Support
 
 
 Hong Kong
 
 
 
 Bioinformatics Manager (at the rank of Technical Manager) in Bioinformatics Core of the Centre for PanorOmic Sciences (CPOS)
 
 (Ref.: 533322) (to commence as soon as possible, on a two-year fixed-term basis with contract-end gratuity and University contribution to a retirement benefits scheme, totalling up to 10% of basic salary, with the possibility of renewal subject to satisfactory performance)
 
 
 
 Come and Join Us
 
 
 
 Centre for PanorOmic Sciences (CPOS) is an academic research-support centre embracing multi-omics and big data biomedical research under the LKS Faculty of Medicine. CPOS core laboratories host state-of-the-art technology platforms with sophisticated equipment supported by over 75 dedicated members. Welcome to visit https://cpos.hku.hk to explore more.
 
 
 
 The Role
 
 
 
 <ul>
 <li>
 Assist the Core Manager with daily operations, strategic planning, and service development
 </li>
 <li>
 Lead and deliver bioinformatics analyses for high-throughput sequencing and multi-omics projects
 </li>
 <li>
 Supervise, train, and mentor junior bioinformaticians and research staff
 </li>
 <li>
 Develop, maintain, and optimise reproducible analysis pipelines and workflows
 </li>
 <li>
 Provide expert consultation to researchers on study design, analysis, and data interpretation
 </li>
 <li>
 Coordinate with other CPOS cores to ensure integrated and efficient service delivery
 
 
 </li>
 </ul>
 
 Qualifications And Qualities
 
 
 
 <ul>
 <li>
 Ph.D. degree in Bioinformatics, Computer Science, Biological Sciences or related disciplines
 </li>
 <li>
 At least 10 years' relevant experience, including a minimum of 3 years in a supervisory or team-lead role
 </li>
 <li>
 Background or experience in a bioinformatics core facility, service platform, or academic setting is an advantage
 </li>
 <li>
 Strong technical skills in Python, R, Linux/Unix, workflow management, and reproducible research practices
 </li>
 <li>
 Expertise in one or more of the following areas: genomics, transcriptomics, single-cell, or epigenomics data analysis
 </li>
 <li>
 Excellent communication skills, proactive, independent and enjoy teamwork
 </li>
 <li>
 Willing to meet new challenges and able to meet tight deadlines
 
 
 </li>
 </ul>
 Shortlisted candidates will be invited to attend an interview.
 
 
 A highly competitive salary commensurate with qualifications and experience will be offered. Other benefits include annual leave, medical benefits, continuing professional development, and free access to on-campus gyms and libraries.
 
 
 The University only accepts online application for the above post. Applicants should apply online at the University&rsquo;s careers site (https://jobs.hku.hk) and upload an up-to-date C.V. Review of applications will start as soon as possible and continue until
 
 October 31, 2025
 
 , or until the post is filled, whichever is earlier.
 
 
 
 Advertised:
 
 Oct 8, 2025 (HK Time)
 
 
 
 Applications close:
 
 Oct 31, 2025 (HK Time)
 
 
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</div>

Bioinformatics Manager (at the rank of Technical Manager) in Bioinformatics Core

Virginia Commonwealth University

<div><div><div><h3 class="jobSectionHeader">Lead Bioinformatics Data Engineer, SOM, Stravitz-Sanyal Institute for Liver Disease
</h3><div><div><ul><li>45000976
</li></ul></div><div><ul><li>907 Floyd Avenue, MCV Main Campus, Virginia, United States, 23284
</li><li>907 Floyd Avenue, VCU Main Campus, Virginia, United States, 23284
</li></ul></div><div><ul><li>Research
</li></ul></div><div><ul><li>Staff
</li></ul></div><div></div><div><ul><li>School Of Medicine MBU</li></ul></div></div><div> 
</div><div>Benefits: All full-time university staff are eligible for VCU&rsquo;s robust benefits package that includes comprehensive health benefits, paid annual and holiday leave granted up front, generous tuition benefits, retirement planning and savings options, tax-deferred annuity and cash match programs, employee discounts, well-being resources, abundant opportunities for career development and advancement, and more.

Unit: SOM

Department: Stravitz-Sanyal Institute for Liver Disease

Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU&rsquo;s sponsored research, the School of Medicine is internationally recognized for patient care and education. All full-time university staff are eligible for VCU&rsquo;s generous benefits package that includes competitive health benefits, paid annual and holiday leave, retirement planning and savings options, tax-deferred annuity and cash match programs, Virginia Retirement System (VRS), professional development &amp; certifications, tuition waiver, parental leave, caregiving leave and community service leave. Learn more about VCU&rsquo;s benefits here: https://hr.vcu.edu/careers-at-vcu/why-work-at-vcu/

Position summary:

Join the Stravitz-Sanyal Institute on the ground floor of an ambitious program to build multi-omics resources for the global liver research community. You will work alongside luminaries and key opinion leaders in the fields of liver and metabolic health to accelerate and translate discoveries in disease biology. You will be the principal engineer who architects, implements, and evangelizes the data engineering stack that turns multimodal data into analysis-ready assets, powering institutional and global research efforts. The role combines deep hands-on work with technical leadership: you will set standards, guide architecture, and mentor peers.

Key responsibilities:
<ul>
<li>Strategic architecture &ndash; Define long-term data storage strategies and governance patterns that guarantee usability and scalability.</li>
<li>Pipeline engineering &ndash; Design and maintain ETL/ELT and workflow-managed pipelines (e.g., Nextflow, Snakemake) that ingest, transform, and harmonize multi-format data.</li>
<li>Cloud &amp; HPC enablement &ndash; Optimize processing on HPC and cloud infrastructure while remaining interoperable.</li>
<li>Data products &amp; APIs &ndash; Collaborate closely with bioinformatics scientists to deliver versioned data products with programmatic access, which feed visualization tools and support statistical workflows.</li>
<li>Quality, security &amp; compliance &ndash; Institute robust validation, provenance capture, and access-control measures. Align with institutional policies.</li>
<li>Technical leadership &ndash; Establish coding standards, CI/CD, infrastructure-as-code, and mentor junior engineers and analysts. Be a champion for a reproducible research culture.</li>
<li>Technology radar &ndash; Continuously evaluate emerging technologies that can support the mission of the Institute.</li>
</ul>
Qualifications:

Minimum Hiring Standards/Qualifications:
Education/Experience &ndash; MSc/PhD in bioinformatics, computer science or related field and<ul><li> 5 years building production pipelines for large-scale omics and biomedical data.</li>
<li>Programming &ndash; Expert in Python (PyData), and SQL. R is a strong plus.</li>
<li>Workflow &amp; DevOps &ndash; Proven experience with workflow DSLs, Docker/Singularity, CI/CD, and IaC.</li>
<li>Cloud &ndash; Hands-on delivery with major cloud platforms.</li>
<li>Bioinformatics expertise &ndash; Deep familiarity with NGS, spatial omics, and imaging formats; experience integrating multi-omics datasets into harmonized schemas. Experience with spatial omics is a significant plus.</li>
<li>Communication &ndash; Ability to translate complex concepts for cross-disciplinary teams and influence technical direction.</li>
<li>Excellent analytical and design skills.</li>
<li>Detail oriented with advanced project management skills.</li>
<li>Good communication and presentation skills.</li>
<li>Demonstrated ability to work in and foster an environment of respect, professionalism and civility with a population of faculty, staff, and students from all backgrounds and experiences, or a commitment to do so as a staff member at VCU.</li>
</ul>
Work environment &amp; benefits
<ul>
<li>Impactful, greenfield build that will accelerate discovery in human health. Close collaboration with world-class clinicians and scientists.</li>
<li>Flexible work model: Richmond-based on-site/hybrid encouraged; open to remote. Progress is the key expectation.</li>
<li>Collaborative culture committed to mentorship and professional growth.</li>
<li>Comprehensive benefits package and competitive compensation.</li>
</ul>
Additional Information:
ORP Eligible: - YES 
Hours / weeks - 40 hours weekly 
Working Title Details: Lead Bioinformatics Data Engineer

VCU Job Title: Sr. IT Architect Engineer

University Code: (24264Y-24266Y) 
University Job Family: Information Technology

The position will remain open until a candidate is selected. 

Salary Range: $120,000 - $160,000 /commensurate with experience

FLSA Exemption Status: EXEMPT

ORP Eligible: YES

Flexible Work Arrangement: HYBRID

Contact Information: 
Contact Name: Demetria Patterson 
Contact Email: demetria.patterson1@vcuhelth.org</div></div></div></div>

Lead Bioinformatics Data Engineer, SOM, Stravitz-Sanyal Institute for Liver Disease

Mount Sinai Health System

<div>Description
A grant-funded Bioinformatician position is available in a lab in the Windreich Department of AI and Human Health at Icahn School of Medicine at Mount Sinai. The Bioinformatician will work with a group of researchers on innovative analyses of genetic disease in electronic health records (EHR). The individual will support research projects by delivering bioinformatics services for medical, genetic, and multi-omic data. The specific project supported by this position focuses on using machine learning and AI methods to detect undiagnosed rare genetic disease in medical databases, including Mount Sinai patients. The ideal candidate will have strong statistical and programming proficiencies with proven expertise in machine learning and deep learning. Good organization and communication skills, with demonstrated ability to productively work as a member of a team. Strong verbal and written communication skills in English are required. 
Responsibilities<ul><li>
Conducts statistical and genetic analyses</li><li>
Uses software to gather, store, manipulate and analyze research data</li><li>
Develops and evaluates predictive models of rare genetic disease</li><li>
Work independently on a variety of bioinformatics analysis projects to support efforts in the lab</li><li>
Participate in the preparation of manuscripts and presentations</li><li>
Other related duties as assigned</li></ul> 

Qualifications<ul><li>
B.S. in Biological Sciences, Bioinformatics, Computer Sciences, Statistics or related discipline; M.S. preferred</li><li>
3 years experience required</li><li>
Working experience with genetics or statistics analysis software and online resources. Experience in programming environments such as Matlab, R statistical package, BioConductor, Perl or C++.</li></ul> 
Employer Description
Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai&rsquo;s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time &mdash; discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients&rsquo; medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News &amp; World Report's Best Hospitals, receiving high &quot;Honor Roll&quot; status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News &amp; World Report&rsquo;s &ldquo;Best Children&rsquo;s Hospitals&rdquo; ranks Mount Sinai Kravis Children's Hospital among the country&rsquo;s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek&rsquo;s &ldquo;The World&rsquo;s Best Smart Hospitals&rdquo; ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization. 
Compensation
The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65000.17 - $87610 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.</div>

Bioinformatician I - Windreich Department of AI & Human Health

Ellison Institute, LLC

The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results.A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit.The Pathogen Mission highlights EIT's transformative approach, using Whole Genome Sequencing (WGS) and Oracle's cloud technology to create a global pathogen metagenomics system. This initiative aims to improve diagnostics, provide early epidemic warnings, and guide treatments by profiling antimicrobial resistance. The goal is to deliver certified diagnostic tools for widespread use in labs, hospitals, and public health.EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges.We are seeking a highly skilled and innovativeSenior Genomics Scientistto lead the establishment of high-throughput genomics capabilities within our Pathogen Program. This pivotal role will focus on developing and optimising robust sequencing workflows using both short-read (e.g., Illumina) and long-read (e.g., Oxford Nanopore Technologies, PacBio) platforms for the sequencing of pathogens.The successful candidate will drive the implementation of end-to-end genomics pipelines, from sample preparation through to sequencing and preliminary data analysis, while also supporting method development and scaling through laboratory automation. The scope of work may extend beyond the Pathogen Program, offering opportunities to collaborate across EIT's broader research initiatives. The position includes line management responsibilities, overseeing a team of 2-3 laboratory scientists, and will play a critical role in advancing EIT's mission to deliver cutting-edge genomic science for real-world impact.Key Responsibilities:<ul><li>Design, evaluate, and implement high-throughput sequencing workflows for pathogen genomics using short- and long-read technologies.</li><li>Develop and optimise novel protocols and methodologies to address emerging research questions and challenges.</li><li>Lead the integration of lab automation systems to streamline sample preparation and sequencing processes.</li><li>Manage day-to-day operations of the sequencing team, including planning, performance tracking, and mentoring of junior scientists.</li><li>Ensure quality control, data integrity, and reproducibility across all stages of the genomics workflow.</li><li>Coordinate closely with bioinformatics teams to facilitate seamless handoff of data for analysis and interpretation.</li><li>Provide scientific leadership and technical insight to support genomics needs across other programs at EIT.</li><li>Keep abreast of technological advances and recommend adoption of relevant new platforms or strategies.</li></ul>Qualifications & Experience:Essential Knowledge, Skills and Experience:<ul><li>PhD in Genomics, Molecular Biology, Biotechnology, or a related field, or equivalent industrial experience.</li><li>Proven track record (5+ years postdoctoral or equivalent industrial experience) in genomics and sequencing technologies.</li><li>Demonstrated expertise in developing and troubleshooting NGS workflows, including both library prep and sequencing protocols.</li><li>Experience with Illumina, ONT, and/or PacBio platforms.</li><li>Strong leadership capabilities with prior experience managing laboratory personnel and projects.</li><li>Excellent organizational, problem-solving, and communication skills.</li></ul>Desirable Knowledge, Skills and Experience:<ul><li>Experience implementing and operating lab automation platforms (e.g., liquid handlers, robotic systems).</li><li>Proficiency in basic bioinformatics and data analysis, with the ability to build or oversee construction of data processing pipelines.</li><li>Familiarity with quality management systems and standard operating procedures in high-throughput laboratory environments.</li><li>Interest in cross-disciplinary collaboration, including applications of genomics in public health, diagnostics, or basic biology.</li></ul>We offer the following salary and benefits:<ul><li>Salary: Competitive salary on offer</li><li>Enhanced holiday pay</li><li>Pension</li><li>Life Assurance</li><li>Income Protection</li><li>Private Medical Insurance</li><li>Hospital Cash Plan</li><li>Therapy Services</li><li>Perk Box</li><li>Electrical Car Scheme</li></ul>Why work for EIT:At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact!Terms of Appointment:<ul><li>You must have the right to work permanently in the UK with a willingness to travel as necessary.</li><li>You will live in, or within easy commuting distance of, Oxford.</li><li>During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.</li></ul><img src="https://www.jobg8.com/Tracking.aspx?jsVBRRiFIxnkLDXZ24LrZutGBLHi9bjlj" width="0" height="0" />

Senior Scientist Genomics - Pathogen

St. Jude Children's Research Hospital

The Computational Biology Genomics Laboratory (CBGL) has an open position for a Senior Scientist. This position will provide the selected candidate with the opportunity to contribute to projects of scientific and institutional importance. The CBGL is a central laboratory supporting principal investigators in the Department of Computational Biology, their collaborators, and multi-institutional partnerships initiated by St. Jude Children's Research Hospital. Current collaborations include the Transcription Collaborative, St. Jude Life, and the Childhood Cancer Survivorship Study. The CBGL supports several areas of faculty research and interest. Including studies on genomic variation in cancer, the development of improved tools for the analysis and detection of pediatric cancer, cell programs in the tumor micro-environment, and the characterization of the properties of single cells during development and in tumor evolution. A portion of the laboratory is currently supporting the St. Jude Life study with the Department of Epidemiology and Cancer Control. Investigations are being conducted at the bulk and single cell level to better understand the molecular underpinnings impacting the quality of life of survivors, such as frailty, and the risk of secondary cancers from cancer treatment during childhood. The selected candidate will utilize their demonstrated experience and problem-solving skills across a broad range of experimental techniques including but not limited to assays in molecular biology, genomics, advanced imaging methods, and tissue processing to generate and analyze high quality data in collaboration with faculty and scientists in the department of computational biology.Job Responsibilities:<ul><li>Coordinate team-based, multi-disciplinary projects independently under overall direction of the PI.</li><li>Build deep understanding of the field and be familiar with current literature in the field and related disciplines.</li><li>Develop new research protocols, techniques, and procedures.</li><li>Identify, process, organize, interpret, review, and report relevant experimental data.</li><li>Monitor data collection and entry methods to meet quality standards.</li><li>Present research to colleagues within and outside the institution; publish as co-author and/or independently draft sections of research manuscripts.</li><li>Guide/make recommendations for optimal lab operations, administration, and training.</li><li>Regularly trains and oversees the work of others in laboratory techniques and procedures.</li><li>Performs other related duties as assigned in order to meet the goals of the department and institution.</li><li>Maintains regular and predictable attendance.</li></ul>Minimum Education and/or Training:<ul><li>Bachelor's degree in relevant scientific area is required</li></ul>Minimum Experience:<ul><li>Ten (10) years relevant work experience is required</li><li>Eight (8) years of relevant work experience is required with a master's degree</li><li>Five (5) years of relevant work experience is required with a PhD</li></ul>Special Skills, Knowledge, and Abilities:<ul><li>Ideal candidates should have hands-on experience with various single cell RNA sequencing methods (droplet-based methods and combinatorial Indexing) and single cell whole genome amplification methods (MDA, PTA).</li><li>Preferably experienced in generating data using spatial transcriptomics platforms such as the Visium and Xenium.</li><li>Ability to train colleagues in new methods.</li><li>Exposure to Immunohistochemistry and Immunofluorescence microscopy.</li><li>Familiarity with cell sorting and cell staining methods.</li><li>Basic understating of command line tools and experience running commercial pipelines such as Cell Ranger and Space Ranger using both cloud applications and computational clusters.</li><li>The ability to identify and implement new methods or protocols related to single cell genomics from literature or commercial vendors.</li><li>Understanding and experience with next-generation sequencing platforms and workflows.</li><li>Perform lab related duties as assigned to meet the goals of the department.</li><li>Hands-on experience in cell biology techniques such as cell culture, in-vitro cell assays, viral transduction, and tissue sample handling.</li></ul>Strongly Preferred Experience:<ul><li>Experience working with applicable regulations and lab protocols preferred.</li><li>Experience working with computerized databases and/or software preferred as applicable.</li><li>Experience in lab and scientific project coordination, maintenance, and other research support activities preferred.</li></ul>About St. Jude:St. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300-faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine's "Best Workplaces in Health Care & Biopharma" and Glassdoor's "Best Places to Work," and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture.CompensationIn recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Scientist - Computational Biology Genomics Laboratory (CBGL).Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.<img src="https://www.jobg8.com/Tracking.aspx?1%2fwdEqK%2fok10VEypkXwgangE7j4oekhUa" width="0" height="0" />

Senior Scientist - Computational Biology Genomics Laboratory (CBGL)

Lantern Pharma

We are seeking a motivated Biopharma Software Engineer to build and maintain the computational infrastructure powering Lantern's AI-enabled oncology drug discovery programs. You will work closely with computational scientists and research teams to create scalable, robust systems that accelerate therapeutic development.The ideal candidate will combine software engineering skills with interest in drug discovery, building cloud-native platforms which enable cutting-edge AI/ML research in precision oncology.RESPONSIBILITIES:<ul><li>Design, build, and maintain in silico molecule pipelines and infrastructure supporting AI/ML drug discovery projects</li><li>Develop scalable data processing workflows for integrating public and proprietary preclinical and clinical datasets</li><li>Implement cloud-based computing solutions for large-scale genomic and chemical data analysis</li><li>Create and maintain APIs and tools enabling scientists to access computational resources and datasets efficiently</li><li>Build data infrastructure for storing, versioning, and querying diverse biomedical databases including genomic, pathway, and drug response resources</li><li>Collaborate with AI drug development scientists to understand computational requirements and optimize infrastructure</li><li>Implement MLOps best practices for model deployment, monitoring, and versioning</li><li>Ensure data security, compliance, and reproducibility across computational workflows</li><li>Document systems architecture, pipelines, and infrastructure for team knowledge sharing</li><li>Support computational scientists in troubleshooting technical issues and optimizing analyses</li></ul>REQUIRED QUALIFICATIONS:<ul><li>Bachelor's or Master's degree in Computer Science, Bioinformatics, Bioengineering, Computational Biology, or related field</li><li>3+ years of experience in software engineering, preferably in biotech, pharma, or healthcare settings</li><li>Strong programming proficiency in Python and familiarity with scientific computing libraries (NumPy, Pandas, scikit-learn)</li><li>Foundational understanding of LLMs and agential chat applications with experience working with OSS models and hosted APIs (OpenAI, Anthropic, etc.)</li><li>Experience with cloud computing platforms (AWS, GCP, or Azure) and containerization technologies (Docker, Kubernetes)</li><li>Knowledge of workflow management systems (Nextflow, Snakemake, Airflow, or similar)</li><li>Familiarity with version control systems (Git) and CI/CD practices</li><li>Understanding of databases (SQL and NoSQL) and data warehousing concepts</li><li>Strong problem-solving skills and ability to work collaboratively with scientists</li><li>Excellent communication skills for technical and non-technical audiences</li></ul>PREFERRED QUALIFICATIONS:<ul><li>Experience with biological data types (genomics, proteomics, chemical structures)</li><li>Knowledge of ML frameworks (TensorFlow, PyTorch) and MLOps tools</li><li>Understanding of serverless engineering and methods of implementation and deployment (Lambdas, AWS Sagemaker)</li><li>DevOps experience with the ability to automate deployment processes and service monitoring</li><li>Familiarity with drug discovery concepts or computational chemistry</li><li>Experience working in remote/distributed team environments</li><li>Understanding of data privacy and compliance requirements (HIPAA, GDPR)</li></ul>Job Type: Full-timeWork Location: In person

Biopharma Software Engineer

The Computational Biology Genomics Laboratory (CBGL) has an open position for a Senior Scientist. This position will provide the selected candidate with the opportunity to contribute to projects of scientific and institutional importance. The CBGL is a central laboratory supporting principal investigators in the Department of Computational Biology, their collaborators, and multi-institutional partnerships initiated by St. Jude Children's Research Hospital. Current collaborations include the Transcription Collaborative, St. Jude Life, and the Childhood Cancer Survivorship Study. The CBGL supports several areas of faculty research and interest. Including studies on genomic variation in cancer, the development of improved tools for the analysis and detection of pediatric cancer, cell programs in the tumor micro-environment, and the characterization of the properties of single cells during development and in tumor evolution. A portion of the laboratory is currently supporting the St. Jude Life study with the Department of Epidemiology and Cancer Control. Investigations are being conducted at the bulk and single cell level to better understand the molecular underpinnings impacting the quality of life of survivors, such as frailty, and the risk of secondary cancers from cancer treatment during childhood. The selected candidate will utilize their demonstrated experience and problem-solving skills across a broad range of experimental techniques including but not limited to assays in molecular biology, genomics, advanced imaging methods, and tissue processing to generate and analyze high quality data in collaboration with faculty and scientists in the department of computational biology. Job Responsibilities:<ul><li>Coordinate team-based, multi-disciplinary projects independently under overall direction of the PI.</li><li>Build deep understanding of the field and be familiar with current literature in the field and related disciplines.</li><li>Develop new research protocols, techniques, and procedures.</li><li>Identify, process, organize, interpret, review, and report relevant experimental data.</li><li>Monitor data collection and entry methods to meet quality standards.</li><li>Present research to colleagues within and outside the institution; publish as co-author and/or independently draft sections of research manuscripts.</li><li>Guide/make recommendations for optimal lab operations, administration, and training.</li><li>Regularly trains and oversees the work of others in laboratory techniques and procedures.</li><li>Performs other related duties as assigned in order to meet the goals of the department and institution.</li><li>Maintains regular and predictable attendance.</li></ul>Minimum Education and/or Training:<ul><li>Bachelor's degree in relevant scientific area is required</li></ul>Minimum Experience:<ul><li>Ten (10) years relevant work experience is required</li><li>Eight (8) years of relevant work experience is required with a master's degree</li><li>Five (5) years of relevant work experience is required with a PhD</li></ul>Special Skills, Knowledge, and Abilities:<ul><li>Ideal candidates should have hands-on experience with various single cell RNA sequencing methods (droplet-based methods and combinatorial Indexing) and single cell whole genome amplification methods (MDA, PTA).</li><li>Preferably experienced in generating data using spatial transcriptomics platforms such as the Visium and Xenium.</li><li>Ability to train colleagues in new methods.</li><li>Exposure to Immunohistochemistry and Immunofluorescence microscopy.</li><li>Familiarity with cell sorting and cell staining methods.</li><li>Basic understating of command line tools and experience running commercial pipelines such as Cell Ranger and Space Ranger using both cloud applications and computational clusters.</li><li>The ability to identify and implement new methods or protocols related to single cell genomics from literature or commercial vendors.</li><li>Understanding and experience with next-generation sequencing platforms and workflows.</li><li>Perform lab related duties as assigned to meet the goals of the department.</li><li>Hands-on experience in cell biology techniques such as cell culture, in-vitro cell assays, viral transduction, and tissue sample handling.</li></ul>Strongly Preferred Experience:<ul><li>Experience working with applicable regulations and lab protocols preferred.</li><li>Experience working with computerized databases and/or software preferred as applicable.</li><li>Experience in lab and scientific project coordination, maintenance, and other research support activities preferred.</li></ul>About St. Jude:St. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300-faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine's "Best Workplaces in Health Care & Biopharma" and Glassdoor's "Best Places to Work," and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture. CompensationIn recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Scientist - Computational Biology Genomics Laboratory (CBGL).Explore our exceptional benefits ! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.<img src="https://www.jobg8.com/Tracking.aspx?4JvFlRdvJgNFnEFiOiU%2fg5IVhoiij23Fp" width="0" height="0" />

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