Associate Scientist - High Throughput Purification

Position: Associate Scientist - High Throughput Purification

Location: Fully Onsite in Spring House, PA

Compensation: $31.47/hr to $38.47/hr.

Exact compensation may vary based on several factors, including skills, experience, and education.

Benefit packages for this role will start on the 1st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.

Benefits: 10 Days of PTO / 6 Sick Days / Paid Holidays

Qualifications:

• A minimum of a bachelor’s degree in Analytical, Synthetic, Organic, Medicinal chemistry or related chemistry degree is required
• Minimum of 2 years analytical or purification HPLC/SFC with mass spectrometry experience required
• Knowledge of modern chromatography techniques, such as HPLC or SFC with MS detector experience.
• Experience with Waters equipment with Masslynx software preferred
• Independent thinking and the ability to effectively collaborate in a highly matrixed environment
• Must be detail oriented with strong organization/communication skills and have good documentation practices

Job Description:

We are seeking a highly motivated BS- or MS-level chemist with small molecule analytical and purification skills to work in our laboratories to advance drug discovery programs toward the clinic. The Associate Scientist will support purification operations in a high‑throughput discovery environment. This role is responsible for routine operation and maintenance of HPLC/MS and SFC/MS systems, performing small‑molecule and peptide purifications, and downstream sample handling including assay ready solution preparation, and ensuring safe, organized lab operations. The ideal candidate is hands‑on, detail oriented, and experienced with chromatography and mass spectrometry workflows. She/he will maintain close interactions with scientists from Discovery Chemistry, Discovery Process Chemistry and Parallel Medicinal Chemistry teams to expedite the compound design-synthesis-test iterations. Strong people skills and the ability to thrive in a team and goal driven environment are key attributes.

Responsibilities:

• Conduct daily system suitability check on analytical and preparative HPLC/MS, SFC/MS
• Perform preliminary method screening experiments, HPLC/MS and SFC/MS–based purifications of small molecules and peptides, post purification QC and downstream handling.
• Maintain instrument in good working condition and perform troubleshooting analysis and maintenance as required; coordinate repairs and preventive maintenance with service provider when needed
• Support lab operations and maintain general lab orderliness
• Assist in the maintenance of a safe working environment and operate in a safe manner
• Other duties and assignments as needed to support the lab operations