Experienced Scientist, Lab Automation & Compound Profiling

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biological Research

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

We are searching for the best talent for our Experienced Scientist, Lab Automation & Compound Profiling position, to be located in Spring House, PA.

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Purpose: The Experienced Scientist, Lab Automation & Compound Profiling will support early drug discovery by delivering and optimizing automated laboratory workflows to support high-throughput screening and compound profiling assays. This hands-on role focuses on day-to-day assay execution, automation system operation, and workflow troubleshooting to ensure timely delivery of high-quality data. The scientist will work closely with automation, assay development, informatics, and project teams to enable robust, scalable compound profiling in support of discovery programs.

You will be responsible for:

• Implementing and supporting automated workflows for high-throughput screening and compound profiling.
• Operating, monitoring, and troubleshooting laboratory automation platforms (e.g., HighRes, Beckman, Agilent, Thermo) and scheduling software (e.g., Thermo Scientific Momentum, Cellario).
• Performing routine liquid handler QC, verifying sample tracking integrity, and supporting data quality assessments.
• Collaborating with informatics and data partners to ensure accurate data capture, metadata management, and downstream analysis.
• Adapting biochemical and cell-based assays for automated execution, including assay miniaturization and workflow onboarding.
• Performing assays on automated systems to support SAR generation, screening, and profiling workflows.
• Troubleshooting assay and workflow issues to minimize downtime and maintain high data quality.
• Partnering with scientific teams to harmonize profiling workflows and support consistent data delivery at scale.
• Reviewing and analyzing assay data to identify trends, performance issues, and follow-up needs.
• Working closely with automation engineers, profiling scientists, and project teams to align execution with discovery timelines.
• Supporting evaluation and implementation of automation hardware and software in collaboration with vendors and internal partners.
• Contributing to continuous improvement efforts focused on assay robustness, automation reliability, and operational efficiency.

Qualifications / Requirements:

• Bachelor’s or Master’s degree in Biological Sciences, Engineering, or related field is required.
• A minimum of 5 years of hands-on experience with laboratory automation and/or high-throughput screening in an early drug discovery environment is required.
• Experience operating robotic liquid handlers and integrated automation systems is required.
• Familiarity with compound profiling, biochemical assays, and/or cell-based assay execution is required.
• Strong troubleshooting skills spanning assays, instrumentation, and automated workflows is required.
• Ability to work optimally in a collaborative, fast-paced laboratory environment while balancing multiple priorities is required.
• Experience with scheduling software (e.g., Cellario, Thermo Scientific Momentum) is preferred.
• Exposure to mass spectrometry or safety assay workflows is preferred.
• Familiarity with Genedata Screener or similar data analysis platforms is preferred.
• Introductory experience with scripting or automation-adjacent coding (e.g., Python or R) is a plus is preferred.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

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Required Skills:

Preferred Skills:

Analytical Reasoning, Clinical Data Management, Communication, Data Analysis, Data Compilation, Data Savvy, Design of Experiments (DOE), Drug Discovery Development, Innovation, Molecular Diagnostics, Pharmaceutical Microbiology, Product Knowledge, Project Management, Scientific Research, Technologically Savvy