Postdoctoral Research Associate, Cancer Center (Full Time)

The Theodorescu Lab within the University of Arizona Cancer Center (UACC) is looking to hire a postdoctoral researcher with a strong background in cancer cell and immunobiology and the tumor microenvironment (TME). In addition to work in cancer cell and immunobiology, projects will also be inducing and characterizing induced pluripotent stem cells (iPSC) with emphasis on mechanisms of transformation orchestrated by genomic alterations found in cancer. The trainee will use techniques of biochemistry, molecular biology, and Crispr/Cas9 technologies, functional genomic approaches (loss of function/synthetic lethal), next generation sequencing including single cell RNA sequencing, together with the use of innovative mouse models we have developed. Examples of the type of work that will be undertaken by the trainee can be seen by our papers by Chen (Nature. 2025 Jun;642(8069):1041-1050), Abdel-Hafiz (Nature. 2023 Jul;619(7970):624-631), Gouin (Nature Commun. 2021; 12;12(1)), Agarwal (Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2102423118) and Tu (Science Adv. 2019; 20;5(2)). Our final goal is to identify novel biomarkers and interventions for cancer that will improve patient outcomes.

This individual would join a vibrant cancer research group. The successful candidate will be a driven, creative, team-oriented individual with a passion for helping discover fundamental cancer biology mechanisms with potential clinical impact, and who can eventually be moved towards clinical settings. We employ a range of in vitro and in vivo approaches and seek individuals with a strong background in cell and molecular biology. Experience gained in our laboratory will help the candidate to become competitive for permanent positions in either academia or industry. We welcome applications from recent PhD or MD/PhD recipients. For more information, please visit: https://cancercenter.arizona.edu/person/dan-theodorescu-md-phd

Outstanding UA benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; access to UA recreation and cultural activities; and more!

The University of Arizona has been recognized for our innovative work-life programs.

• Design and perform experiments. Keeps detailed experimental records and documentation and analyze the results with the Principal Investigator (PI).
• Develop, adapt, and implement new research techniques and protocols.
• Analyze, interpret, summarize and compile data.
• Perform routine and complex laboratory procedures throughout training period.
• Assist in preparation of grant proposals with the PI but is not responsible for generating grant funds.
• Participate in publications and presentations as author or co-author.
• Meets with PI on a regular basis to discuss research progress and plans.
• May be asked to write small grant proposals or NRSA/T32 applications.
• Spends about 75% of time on bench research experimentation and 25% of time on writing articles/analyzing data/online research.

Knowledge, Skills, and Abilities:

• Ability to work semi-independently on research projects within an area of specialization.
• Thorough technical and theoretical knowledge of research project and the objectives.
• Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection and analysis.

• Doctorate (PhD or MD/PhD) in cancer molecular biology or cell biology or immunology.

• Outstanding publication record from prior graduate and/or postgraduate training and/or existing extramural funding.

Application: The online application should be completed in its entirety. Blank or missed information may be considered an incomplete submission.

Cover Letter: Should clearly indicate how your skills and professional employment experience meet the Minimum and the Preferred qualifications (if applicable).