Principal, Data Engineer

The Principal, Data Engineer builds data infrastructure, leads technical initiatives, and mentors junior team members while driving data-driven solutions across the organization.
As a Principal, Data Engineer, a typical day might include the following:
Design complex data engineering solutions and define standards
Mentor junior engineers and drive infrastructure innovation
Build scalable, secure data pipelines with robust monitoring
Optimize ETL/ELT workflows for large-scale data processing
Architect end-to-end data pipeline solutions from ingestion to consumption
Implement real-time and batch processing systems to handle diverse biotech data streams
Design fault-tolerant pipelines with appropriate error handling and recovery mechanisms
Establish CI/CD practices for data pipeline deployment and testing
Develop data transformation logic to support analytical and operational needs
Integrate disparate data sources including laboratory instruments, clinical systems, and external APIs
Implement data validation frameworks to ensure data integrity throughout the pipeline
Manage and organize large datasets
Ensure data quality and accessibility for data analysts
Implement data lake and data warehouse architectures
Monitor data pipeline performance and troubleshoot issues
Maintain efficiency and reliability of data systems
Implement observability solutions for pipeline monitoring
Develop automated alerting systems for pipeline failures or anomalies as needed
Build and leverage GenAI solutions to improve performance, speed and efficiency of data engineering team
Document data processes and systems as required
Ensure compliance with data governance policies

This role may be for you if you have:
Strong Python, Java, or Scala programming skills
Deep SQL expertise and relational database experience
NoSQL and big data technology experience (Hadoop, Spark, Kafka)
Proficiency in data modeling and schema design
Knowledge of data security and compliance requirements in regulated environments
Familiarity with Biotech Enterprise Systems (MES, LIMS, QMS)
Excellent communication skills
Knowledge of MCP and Orchestration platforms related to AI/GenAI
Proficiency in star schemas and data modeling tools
Knowledge of industry regulatory requirements (CFR Part 11, GxP, CSA)
Stream processing experience (Kafka, Flink)
Cloud certifications
In order to be considered for this position, you must hold a BA/BS in Computer Science, Bioinformatics, or related field and
Principal: 8+ years meaningful experience or equivalent combination of education and experience.
Staff: 10+ years relevant experience or equivalent combination of education and experience
Experience in biotech, pharmaceutical, or other life sciences industries preferred
Cloud platform experience (AWS, Azure) preferred
Experience with workflow orchestration tools (Airflow, Luigi, Prefect, or similar)
Experience with containerization technologies
Experience with scientific data management systems
Experience with using GenAI to enhance own work
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually) $101,800.00 - $194,500.00