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Research and Senior Research Associate - Antibody Drug Conjugation (ADC)/Medicinal
Ahmedabad, India
Job Description
ADC (Antibody Drug Conjugate) R&D
ADC (Antibody Drug Conjugate) R&D
- Synthesis and purification of complex antibody drug conjugate (ADC) molecules
- Synthesis of different type of linkers - using natural and un-natural amino acids, PEGs
- Synthesis of high potent drug molecules – payloads
- Purification of complex and large molecules by flash column and HPLC
- Handling various type chemistry with different payloads
- Interpretation and characterization of higher molecular weight compounds
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Minimum 3 years in CRO Industry
- Responsible to perform routine organic synthesis. (mg to gram scale) & work independently under the guidance of the leader.
- Independently support the scientific team with instrumentation and equipment operation and maintenance.
- Able to understand & interpret various instruments like NMR, Mass, HPLC.
- Instrument purification like Combiflash, big columns, column packing. Deciding the mobile phase for purification.
- Independently handling all types of glassware assembly arrangement, reaction reagent charging, maintaining temperature, nitrogen, etc.
- Should be able to understand the written instruction from the scientist including patents and reprints where procedure highlighted by scientists.
- To train and support the team members.
- Meticulous Documentation & proper data management.
- To maintain the record book of the work done like purification or reaction.
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1-4 years of experience in CRO Industry
- Strong organizational, project management and problem-solving skills with impeccable multi-tasking abilities.
- Exceptional interpersonal skills.
- Friendly and professional demeanor.
- Ability to write reports and prepare spreadsheets and presentations.
- Excellent organizational skills with an ability to think proactively and prioritize work.
- Proactive, highly motivated with a "can-do" attitude.
- Strong and accurate attention to detail.
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