Scientist 2- 202505-110898 Scientist 3, Translational Medicine (Immunology and Respiratory)

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The Respiratory group in Translational Medicine at Genentech is seeking a highly talented, driven and motivated lab-based Scientist to support our research and clinical development activities in immunology and respiratory diseases. Our department is responsible for defining and executing biomarker strategies in our clinical trials, and using human clinical translational research to generate novel target and biomarker approaches. Through our clinical trials, as well as our translational research efforts, our group identifies and implements biomarkers to evaluate disease heterogeneity, target engagement, mechanism of action, and disease modification.

The successful candidate will be expected to work independently and collaboratively supporting clinical development and translational research for immunology and respiratory diseases, providing scientific and technical expertise and generating high quality data through rigorous scientific approaches. Excellent communication skills will facilitate fruitful and open collaborations with other functions including Research, Bioanalytical Assay Science, Diagnostics, Clinical Pharmacology, Clinical, Biostatistics and Computational Sciences. The successful candidate will be expected to present their work to the department, cross-functional teams, internal review committees and external conferences.

The Opportunity:

As an integral member of this dynamic team, you will be:

• Discovering and evaluating candidate targets or biomarkers

• Developing and implementing biomarker assays in preclinical models and clinical trials

• Evaluating new technologies as potential novel biomarker assay platforms

• Analyzing large data sets using available analysis tools

• Documenting experiments and studies in lab notebook

• Communicating findings to their manager and key stakeholders

• Coordinating interdepartmental and/or external collaborations

• Performing other duties as assigned

Who you are:

Strong candidates for this position will meet most of the following requirements:

• BS or MS degree, in respiratory, immunology, pharmacology, molecular biology, biochemistry or related field (BS Degree with 2-5 years; Master’s degree with 0-2 years research/professional experience in relevant fields)

• At least 3 years of relevant experience in immunology, inflammation and/or respiratory disease research, or related diseases.

• Familiarity with a broad spectrum of laboratory techniques, such as cell culture, ELISA, qPCR, cytokine profiling, molecular biology, transcriptomics, LC/MS, flow cytometry, NGS, iPSC/organoid or other complex in vitro culture systems, and/or human whole blood assays, and handling human / preclinical samples is required

• Familiarity in assay development is required

• Preferred candidates will have experience with bioinformatics analysis of laboratory-generated data, including high-dimensional data such as genome sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics.

• Able to independently design, execute and interpret experiments in a lab-based setting.

• Excellent written and oral communication skills, as evidenced by publication or internal/external presentations and a seminar during candidacy.

• Excellent time management skills and willing to work in a collaborative environment.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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