Scientist II, Protein Biology

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

About the company

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies & Services makes it easier for customers.

About Team: Antibody team

The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is sophisticated product development and creation of product specific information to promote research use.

Role & Responsibilities

Role:

To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, and cell biology methods.

Responsibilities:

• Work on single cell sorting.
• Provide scientific inputs towards antibody development using recombinant DNA technology
• Lead projects or workflows in new antibody development programs with vast experience in experimental planning and execution to meet the program objectives
• Design and experimental execution, data analysis and data presentations
• Serve as domain authority in cell sorting and immunology. With good knowledge of molecular biology and protein biology to provide inputs and guidance towards driving innovation and cross team engagement with colleagues of different background.

Candidate Requirement:

Education & Experience levels:

Applicants should have Masters with over 5 years relevant experience or PhD with greater than 2 years’ experience in a life sciences field with a strong focus on Immunology and molecular biology.

Nature of experience:

• Strong background in flow cytometry preferably cell sorting. Including immunophenotyping, multicolor flow cytometry and panel design, rare population analysis.
• Understanding of cytometry data analysis techniques and proficiency with flow cytometry analysis software (e.g. FlowJo, FCS Express)
• Ability to process tissue and isolate cells, particularly mammalian PBMCs and mouse splenocytes
• Having hands on experience with monoclonal antibody development methods using one or more of the following technologies would be an advantage: single B cell sorting, phage display, recombinant technology
• Proficient in molecular biology workflows such as high-throughput molecular cloning, plasmid vector construction, PCRs, Restriction digestion, Ligation, Transformation, Mini and maxi preps, sequencing would be preferred.
• Experience in authoring and optimizing standard operating procedures.
• Skills for identifying deviations from expected outcomes, solving and suggesting alternatives
• Excellent written and verbal presentation skills
• Ability to provide technical trouble shooting to resolve scientific problems.
• Proficient in software or platforms for MS Office and statistical software such as GraphPad Prism.
• Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging research protocols and techniques are preferred.

The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate with the ability to work with varied colleagues.

Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

ThermoFisher is committed to crafting a diverse work environment that values and respects individuals from all backgrounds.