proteomics scientist

Broad Institute

<div><div><div><div><h3 class="jobSectionHeader"><b>General information
</b></h3></div></div><div><div><div><div>Location
</div><div>Cambridge, MA
</div></div><div><div>Ref #
</div><div>43204
</div></div><div><div>Job Family
</div><div>Research
</div></div><div><div>Workplace
</div><div>On-Site
</div></div><div><div>Date published
</div><div>11/10/2025
</div></div><div><div>Time Type
</div><div>Full time
</div></div><div><div>Pay Range
</div><div>70,000.00 - 92,667.00 Usd Annual
</div></div></div></div></div><div><div><div><h3 class="jobSectionHeader"><b>Description &amp; Requirements
</b></h3></div></div><div><div><div><div><p>The Proteomics Group (Carr/ Udeshi Lab) at the Broad Institute of MIT and Harvard is looking for a highly motivated postdoctoral associate to develop and apply state-of-the art mass spectrometry-based proteomics technology to address compelling questions in biology, chemistry and clinical medicine in a highly collaborative setting with groups in the greater Broad scientific community and beyond. The specific research areas of immediate interest that this scientist could drive include:</p><div><ul><li><br>
proteogenomic studies of a wide range of cancers</li><li>detailed studies of cellular signaling networks related to protein phosphorylation, ubiquitylation or acetylation</li><li>chemical proteomics technologies such as thermal profiling and cell surface proteomics</li></ul>
to unveil intracellular and cell-surface protein drug targets<br>
<ul><li>developing biological understanding of response and resistance to therapy</li></ul></div><p><br>
Successful candidates will work in one or more of these areas together with an interdisciplinary team of clinicians, biologists, computational and proteomics scientists to deeply characterize and understand the proteomes of tumor-derived material, cells and biofluids.</p><p><br>
The Broad Institute is a world-leading non-profit research organization dedicated to realizing the promise of the post-genomic era for human benefit. Located in Cambridge, MA with strong ties to MIT, Harvard, and world class Boston hospitals, the Broad Institute brings together scientists of diverse backgrounds to solve critical problems in biology and medicine in an interdisciplinary manner.</p><p></p><p><br>
The Broad Institute, and the embedded Proteomics Group, have an outstanding track-record in training the next generation of research scientists. We (www.broadinstitute.org/proteomics) have a very strong track record in developing and applying proteomic technologies critical to address important questions in biology and medicine. We collaborate with top-level international researchers throughout the world, and results of these studies and our technology developments are published in top-tier journals.</p><div><b><br>
Qualifications Candidates must have:</b><br>
<ul><li>an Ph.D. or MD, PhD in areas such as analytical chemistry, molecular biology, biology, biochemistry, computational biology or preferably interdisciplinary sciences merging laboratory and bioinformatic skills</li><li>excellent scientific productivity, evidenced by high-quality research publications in peer- reviewed journals</li><li>track record of conducting independent and creative research</li><li>analytical aptitude for devising innovative scientific or technical solutions</li><li>excellent verbal and written communication skills</li></ul><br>
<b>
Hands-on skills and knowledge in one or more of the following areas would be considered an advantage:</b><br>
<ul><li>state-of-the-art mass spectrometry-based proteomics</li><li>expertise in statistical and/or computational analysis of large-scale proteomic or genomic data</li><li>analysis of cell signaling pathways/networks</li><li>cell biology/ biochemical methods to understand protein function</li><li>domain expertise in a disease area such as cancer, metabolic or infectious disease</li></ul></div>
</div></div><div><div><div>The expected base salary range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.</div><div>
</div><div>
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.</div><div></div><div><br>
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.</div><div></div><div><br>
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.</div></div></div></div></div></div></div><div></div>

Postdoctoral Associate - Proteomics Group

IndiaBioscience

<div>
 <strong>
  Project
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  <br/>
 </strong>
 <strong>
  Normative baseline characterization of body composition and metabolic parameters to assess growth and development in children: A multi-site study on the impact of malnutrition
  <br/>
  <br/>
 </strong>
 <strong>
  Profile
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  <br/>
 </strong>
 The Indian Institute of Science Education and Research (IISER) Pune is a premier institute dedicated to research and teaching in the basic sciences. It was established in 2006 by the Ministry of Human Resource Development (renamed Ministry of Education in August 2020). In 2012, IISER Pune was declared as an Institute of National Importance by an Act of Parliament.
 <br/>
 <br/>
 Institute invites applications from Indian nationals for the following post purely on temporary and contractual basis under funded project.
 <br/>
 <br/>
 The incumbent is expected to handle mass spectrometry-based proteomics experiments, setting up cell models and biochemical assays for validating findings from human clinical samples, and analysis of large proteomic datasets.
 <br/>
 <br/>
 <strong>
  Duration
  <br/>
  <br/>
 </strong>
 Initially for a period of one year, extendable for further period subject to satisfactory performance of the incumbent and continuation of the project.
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 <strong>
  Money
  <br/>
  <br/>
 </strong>
 Rs. 56,000/- 30 PERCENT House Rent Allowance.
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 <strong>
  Qualification
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Post-graduate degree in Life Sciences / Biological Sciences with minimum 60 PERCENT marks / first class or equivalent grade.
  </li>
  <li>
   Ph.D. in Life Sciences / Biological Sciences or related field.
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Experience
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Experience with molecular biology and biochemical assays, or mass spectrometry-based proteomics, or writing codes (in MATLAB or R) to analyze large omics-datasets.
  </li>
  <li>
   Having publications (peer-reviewed papers or preprints) showing the experience mentioned above.
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  To Apply
  <br/>
  <br/>
 </strong>
 Interested candidates should send the application by email in the prescribed format available below advertisement by email (convert into PDF Format) addressed to bio_app@acads.iiserpune.ac.in on or before 10.11.2025. Please mention Project Research ScientistI and Advt. No. 612025 in the subject line of the email.
 <br/>
 <br/>
 For more details click here.
</div>


Project Research Scientist-I - IndiaBioscience

ONE NUCLEUS

<p>3 Month Contract Near Cambridge UK Scientist / Bioanalytics, PK assays, MSD</p> <p>Candidates will need to be available to start quickly, be able to be based in Cambridge, have right to work in the UK and have experience with the above techniques. Some training could be given to certain areas lacking.</p> <p>Please send CV's direct via LinkedIn to Louisa Hodgson in the first instance and for suitable candidates she will organise a call to discuss more insight. This role will support a leader in a time of need, so if you can confidently help us with the above then we would welcome hearing from you with your CV.</p> <p>Candidates without the immediate right to work in the UK unfortunately cannot be considered.</p>

Scientist / Bioanalytics, PK assays, MSD

Regeneron

<div><p>We are seeking an <b>Associate Scientist </b>to join Protein Development group within our Therapeutic Proteins department. The candidate will join our ongoing efforts towards purification and characterization of protein reagents.
</p><p></p><p><b>As an Associate Scientist, a typical day might include:
</b></p><ul><li>Purifying therapeutic reagents and antibodies for ongoing therapeutic programs using standard purification systems and automated equipment
</li></ul><ul><li>Conducting protein purification and characterization by liquid chromatography such as affinity, IEX, HIC, and SEC.
</li></ul><ul><li>Doing protein characterization of reagents by Western blotting, SDS-PAGE electrophoresis, CE-SDS, SEC chromatography, spectrophotometry, etc.
</li></ul><ul><li>Entering, analyzing, and documenting data of purified characterized reagents in LIMS and presentations
</li></ul><ul><li>Communicating results clearly and concisely to manager and peers
</li></ul><p></p><p><b>This role might be for you if you:
</b></p><ul><li>Can work productively in a fast-paced collaborative team
</li></ul><ul><li>Have strong organizational skills and excellent verbal and written communication skills
</li></ul><ul><li>Enjoy working productively in a fast-paced collaborative environment
</li></ul><ul><li>Have an eye for detail and pride yourself on the quality of your work
</li></ul><ul><li>Work on current problems while thinking of future solutions
</li></ul><p></p><p><b>To be considered for this role, </b>you must have at least a BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 0-2 years of relevant experience in protein purification/characterization. We need someone with a strong background in protein chemistry. Must have experience with liquid chromatography and isolation techniques such as Affinity, IEX, HIC, and SEC. AKTA Avant experience preferred. Experience purifying bispecific antibodies is very advantageous. Characterization experience of reagents by Western blotting, SDS-PAGE electrophoresis, CE-SDS, and SEC chromatography is also required. Must have experience with data entry and notebook keeping using ELN.
</p><p></p><div><div><div><div><div><div><div><p>Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries&rsquo; specific benefits, please speak to your recruiter.
<br>
Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron&rsquo;s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron&rsquo;s on-site policy and expectations for your role and your location.<br>
<br>
</p><p></p><p>Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
</p><p></p><p>For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
</p><p></p><p>Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
</p><p></p><p><b>Salary Range (annually)
</b></p></div></div></div></div></div></div></div>$80,300.00 - $131,100.00</div>

Associate Scientist - Protein Development

CVJ-Centre for Synthetic Biology and Biomanufacturing

<p><b>POSITION OVERVIEW</b></p><p>We are seeking a highly motivated Scientist in Bio AI to join our cutting-edge research and innovation team at the intersection of biology, artificial intelligence, and data-driven discovery. The ideal candidate will apply AI/ML methods to accelerate insights in genomics, systems biology, synthetic biology, and biomanufacturing. This role offers the opportunity to work in a highly interdisciplinary environment, driving innovation in healthcare, sustainability, and the bioeconomy.</p><p><b>KEY RESPONSIBILITIES</b></p><p>The responsibilities of the scientist would include, but are not limited to, the following</p><p>1. Conduct high-impact translational research using classic computational tools, AI, and quantum tools to design novel molecules and pathways for health, food, and environmental applications.</p><p>&middot; Integrate multi-omics data to model virtual pathways and cells.</p><p>&middot; Build AI/ML models for genomics, proteomics, metabolomics, imaging, and multi-omics integration.</p><p>&middot; Develop predictive and generative models for protein design, pathway optimization, drug discovery, and biomanufacturing.</p><p>&middot; Collaborate with experimental teams to validate AI-driven predictions in the lab.</p><p>&middot; Create knowledge graphs and data pipelines to structure biological insights.</p><p>&middot; Drive innovation through high-impact publications and intellectual property (patents, algorithms, pipelines).</p><p>2. Publish research findings in good journals and present at international conferences.</p><p>3. Participate in grant writing and fundraising activities.</p><p>4. Foster collaborations with global academic institutions and industry leaders.</p><p>5. Contribute to the academic mission by designing courses, teaching and mentoring students in bio-AI, computational biology, and data-driven biodesign.</p><p><b>QUALIFICATIONS AND EXPERTISE</b></p><p>&middot; PhD or equivalent in Computational Biology, Bioinformatics, Computer Science, AI/ML, Systems Biology, or related fields.</p><p>&middot; Strong expertise in machine learning, deep learning, or generative AI, with applications in biology or chemistry.</p><p>&middot; Proven experience in handling large-scale biological datasets (genomic, proteomic, imaging, multi-omics).</p><p>&middot; Proficiency in programming (Python, R, TensorFlow, PyTorch, or equivalent).</p><p>&middot; Strong understanding of molecular biology, biochemistry, or systems biology.</p><p>&middot; Track record of scientific publications and/or patents.</p><p>&middot; Excellent communication skills and ability to thrive in a collaborative, interdisciplinary team.</p><p><b>BENEFITS AND OPPORTUNITIES</b></p><p>&middot; Opportunity to work at the frontier of AI and life sciences, shaping the future of biomanufacturing and healthcare.</p><p>&middot; Access to state-of-the-art computational and experimental facilities.</p><p>&middot; Competitive salary and benefits package.</p><p>&middot; Career growth through publications, patents, and translational projects with industry partners.</p><p>&middot; Be part of an internationally connected ecosystem, with collaborations spanning academia, startups, and industry leaders.</p><p>&middot; A dynamic workplace that values innovation, interdisciplinary collaboration, and societal impact.</p><p><b>APPLICATION PROCESS</b></p><p>&middot; A cover letter outlining Research Plan, Teaching Statement</p><p>&middot; A detailed CV, including publication record</p><p>&middot; Contact details of three professional references</p><p>&middot; Applications will be accepted until the position is filled</p><p>Submit application to: <b>connect@cvjsynbio.org</b></p><p><i>Note: All applications will be thoroughly reviewed - </i><i><b>only</b></i> <i>shortlisted candidates will be contacted for an interview.</i></p><p>Job Type: Full-time</p><p>Work Location: In person</p>

Scientist BioAI

Tox Tech

<p><b>Job Summary</b><br/>We are seeking a dedicated and detail-oriented Chemist to join our team. Key functions of the position in-depth knowledge and operational experience of AKTA Avant FPLC system with UNICORN software for the purpose of purification of bacterial and plant-derived toxins. Experience with ion exchange chromatography (CEX, AEX), hydrophobic interaction chromatography (HIC), size exclusion chromatography (SEC) and affinity chromatography is required. Specific duties include the preparation of custom affinity resins (antigen immobilization) to purify antigen-specific antibodies, FPLC system operations and maintenance and carry out QA/QC established assays as assigned. The position requires passing of a federal background check.</p><p><b>Responsibilities</b></p><p>Assist with the optimization of multi-step purification methods</p><p>Run and maintain AKTA Avant FPLC system including installation and maintenance of FPLC hardware</p><ul><li>Knowledge and operation of Unicorn software system</li><li>Operate chromatography systems: Ion exchange chromatography (CEX, AEX Hydrophobic interaction chromatography (HIC, Size exclusion chromatography (SEC) Affinity chromatography</li><li>Prepare and maintain affinity resins, samples, solutions/buffers . Hand pack chromatography columns. Perform routine quality control testing of chromatography columns and equipment. Determine dynamic binding capacity (DBC) of chromatography columns</li><li>Maintain organized laboratory records and logs</li><li>Assist with development of Standard Operating Procedures</li><li>Follow safety procedures</li><li>Collaborate with cross-functional teams to support manufacturing processes and quality control initiatives.</li><li>Maintain accurate records of experiments, results, and observations in compliance with laboratory protocols.</li><li>Ensure the cleanliness and organization of the laboratory workspace.</li></ul><p><b>R</b>equirements</p><ul><li>Bachelor&rsquo;s degree in chemistry, microbiology, biochemistry or similar science with a minimum of 3 years' experience working with AKTA FPLC purification systems</li><li>Extensive knowledge of FPLC instrumentation and LC separation techniques for native proteins</li><li>Prior demonstrated experience developing and validating/verifying purification procedures under design control using a requirements-driven, risk-based approach within the biotech industry or clinical laboratory.</li><li>Proficient computer skills (UNICORN, Microsoft, Teams)</li><li>A strong track record of independence, productivity and creative problem-solving</li><li>Strong problem-solving skills and attention to detail are essential for success in this role.</li><li>Excellent communication skills to effectively collaborate with team members and stakeholders.</li></ul><p>Join us in our commitment to scientific excellence as we strive to innovate and improve our products</p><p>Job Type: Full-time</p><p>Benefits:</p><ul><li>Health insurance</li><li>Paid time off</li></ul><p>Work Location: In person</p>

Protein Chemist

<p><b>POSITION OVERVIEW</b></p><p>We are seeking a self-driven Scientist in Metabolic Engineering to design, construct, and optimize microbial and eukaryotic hosts for applications in health, food, environment, and sustainable biomanufacturing. The role involves developing innovative metabolic pathways, leveraging advanced tools in synthetic biology, and collaborating with multidisciplinary teams to translate designs into functional biological systems.</p><p><b>KEY RESPONSIBILITIES</b></p><p>The responsibilities would include, but are not limited to, the following</p><p>&middot; Engineer prokaryotic and eukaryotic organisms for production of high-value molecules, enzymes, and biomaterials.</p><p>&middot; Design, build, and optimize heterologous metabolic pathways using genetic engineering, CRISPR, and synthetic biology toolkits.</p><p>&middot; Apply systems biology and computational modeling to guide strain design and pathway optimization.</p><p>&middot; Conduct multi-omics analyses (transcriptomics, proteomics, metabolomics, fluxomics) to identify bottlenecks and improve yields.</p><p>&middot; Integrate high-throughput screening and automation to accelerate strain development.</p><p>&middot; Collaborate closely with bioinformatics, AI, and bioprocess engineering teams to validate engineered pathways.</p><p>&middot; Publish in peer-reviewed journals and contribute to IP generation (patents, proprietary strains, pathways).</p><p>&middot; Mentor junior researchers and contribute to teaching/training in synthetic biology and metabolic engineering.</p><p><b>QUALIFICATIONS AND EXPERTISE</b></p><p>&middot; PhD in Synthetic Biology, Metabolic Engineering, Microbiology, Biochemical Engineering, Molecular Biology, or related field (or equivalent industry experience).</p><p>&middot; Strong expertise in prokaryotic (e.g., E. coli, Bacillus) and eukaryotic (e.g., yeast, filamentous fungi, microalgae, mammalian cells) systems.</p><p>&middot; Hands-on experience in CRISPR/Cas genome editing, pathway construction, strain optimization, and high-throughput workflows.</p><p>&middot; Proven ability to analyze and interpret omics datasets for strain improvement.</p><p>&middot; Familiarity with bioprocess scale-up, fermentation strategies, and industrial biotech applications is an advantage.</p><p>&middot; Track record of publications, patents, or demonstrated impact in metabolic engineering projects.</p><p>&middot; Excellent problem-solving abilities, strong communication skills (both written and verbal), and the ability to work effectively in a team. A high degree of independence and initiative is essential.</p><p><b>BENEFITS AND OPPORTUNITIES</b></p><p>&middot; A competitive salary and comprehensive benefits package are offered, commensurate with experience.</p><p>&middot; Work in a state-of-the-art synthetic biology and biomanufacturing center with cutting-edge facilities.</p><p>&middot; Collaborate with interdisciplinary experts in AI, quantum biology, and bioengineering.</p><p>&middot; Opportunity to translate research into real-world applications in health, food, environment, and sustainability.</p><p>&middot; Professional growth through publications, patents, and leadership in high-impact projects.</p><p>&middot; Engage in teaching, mentoring, and capacity building for the next generation of bioengineers.</p><p><b>APPLICATION PROCESS</b></p><p>&middot; A cover letter outlining Research Plan, Teaching Statement</p><p>&middot; A detailed CV, including publication record</p><p>&middot; Contact details of three professional references</p><p>&middot; Applications will be accepted until the position is filled</p><p>Submit application to: <b>connect@cvjsynbio.org</b></p><p><i>Note: All applications will be thoroughly reviewed - </i><i><b>only</b></i> <i>shortlisted candidates will be contacted for an interview.</i></p><p>Job Type: Full-time</p><p>Work Location: In person</p>

Scientist

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