Senior R&D Scientist - Inhalation Development

EVA Pharma is hiring Senior Scientist for the inhalation development team. The role will be responsible for hands-on formulation development, analytical characterisation, scale-up, and process validation of Generic Dry Powder Inhaler products — including capsule-based, blister-based, reservoir-based, dual capsule/blister inhalers, and generic nebulizers.

The role requires deep technical expertise in powder engineering and inhalation science, with the ability to independently drive development activities.

Key responsibilities:

DPI Formulation Development

• Design and optimise DPI, MDI & Nebulizer formulations for capsule-based, blister-based, reservoir-based, and dual capsule/blister inhalers
• Develop and evaluate device-formulation compatibility across all inhalation platform types
• Apply particle engineering techniques — micronization, spray drying, powder blending — to achieve target aerodynamic profiles
• Develop generic nebulizer formulations alongside DPI programmes
• Execute feasibility, prototype, and optimisation studies with full scientific documentation

Analytical Characterisation

• Perform aerodynamic characterisation using NGI and DUSA for in-process and release testing
• Apply laser diffraction and other particle sizing tools to characterise powder properties
• Execute and interpret analytical data to guide formulation decisions and device selection
• Support development and qualification of analytical methods specific to inhalation products

Scale-Up & Process Validation

• Lead scale-up activities from lab to pilot and commercial manufacturing scale
• Define and optimise critical process parameters using QbD principles, DoE, and FMEA
• Execute process validation protocols and compile validation reports
• Identify and mitigate technical risks through the development lifecycle

Tech Transfer to Manufacturing

• Prepare technology transfer packages including formulation, process, and analytical documentation
• Support on-site transfer activities at manufacturing scale and resolve technical deviations
• Collaborate with production and engineering teams to ensure successful handover

Bioequivalence Support

• Contribute to bioequivalence protocol design for generic DPI products versus reference innovators
• Prepare formulation and device rationale sections required for BE study initiation
• Support interpretation of BE data from a formulation science perspective

Scientific Guidance

• Provide day-to-day technical guidance to 1–3 junior researchers working on DPI projects
• Review experimental data, troubleshoot issues, and validate scientific conclusions
• Maintain up-to-date knowledge of inhalation science, device technologies, and industry trends

Education:

PhD or Master's degree in Pharmaceutics, Pharmaceutical Sciences, or related field

Overall Experience:

8–10 years of hands-on experience in DPI development within the pharmaceutical industry

Technical skills:

• Proven formulation experience across capsule-based, blister-based, reservoir-based, and dual DPI formats
• Hands-on expertise with NGI, DUSA, and laser diffraction for aerodynamic characterisation
• Particle engineering skills: micronization, spray drying, and powder blending
• Scale-up and process validation experience for inhalation products
• Experience preparing technology transfer documentation for manufacturing handover
• Contribution to BE protocol design or study initiation for generic DPI products
• Familiarity with QbD, DoE, and FMEA-based risk management