Senior Scientist, Precision Medicine

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Regeneron is advancing its pipeline portfolio using a data-driven human translational approach. As part of this initiative, the Precision Medicine team is integrated with Discovery Research and Clinical Development teams to promote early adoption of biomarker strategy to guide clinical translation. The team collaborates with Clinical Sciences colleagues to develop the clinical experimental sciences (CES) studies for generating clinically testable, mechanistic hypotheses for each molecule, including developing scientific rationale for initial and new indications for PoC. Precision Medicine leads the biomarker strategy and execution, to achieve proof of mechanism/concept in early clinical trials. The team also implements Precision Medicine strategies, including patient stratification and selection, to support late-stage clinical programs and companion diagnostics. Our team includes Precision Medicine Strategy Leads, Precision Medicine Operations specialists, as well as Quantitative Translation and Companion Diagnostics scientists.

This is a statistical computational role that falls within Precision Medicine Quantitative Translational Sciences (PMQTS), the analytical arm of Precision Medicine. We are looking for a motivated individual who can conduct clinical trial data management and data analysis in an open and collaborative working environment. This role will encompass exploratory analyses and visualization of omics, EHR, wearable sensor, imaging, and other biomarker data. This position is also involved in the development of tools and dashboards for processing, analyzing, querying, visualizing, and cleaning data. The individual will work collaboratively with internal and external groups to assure data integrity, best practices for analytics and data visualization, and offering strategic insights to drive Precision Medicine objectives. Successful applicant will join a team of computational scientists from diverse training backgrounds, including but not limited to Statistics, Genetics, Multi-Omics, Proteomics, Chemistry, Engineering, Machine Learning, and Computer Science.

As a Senior Scientist in Precision Medicine, a typical day may include the following:

Liaise with Precision Medicine Quantitative Translational Sciences to analyze biomarker data types across a range of Precision Medicine and biomarker studies.
Provide computational and technical expertise on data cleaning and data visualization.
Integrate complex datasets to perform statistical analysis on exploratory biomarker data and clinical endpoints. Use technical tools, language, or custom coding and systems analysis to clean data and select or create datasets for analysis.
Understand and follow data quality concepts and best practices and tools. Identify data anomalies and work with data stewards in other units to perform root cause analysis on data quality issues.
Assist in the preparation of scientific presentations, manuscripts, and reports, including the preparation of quality checked tables and graphs depicting research results.
Effectively communicate analytical plans and timelines for multiple concurrent projects with study team members.
Develop, benchmark, and implement new computational workflows as necessary
Maintain best coding and data cataloguing practices for business consistency and scientific reproducibility.

This role may be for you if:

You are comfortable working on teams with an open, collaborative culture.
You are self-directed with the ability to work and operate independently within a tight deadline environment.
You are agile and flexible in daily routines and have excellent interpersonal skills, both in person and over the phone.
You possess a high degree of creativity, latitude, and attention to detail.
You can multi-task, work on multiple projects, and possess strong organizational skills.
You have experience with statistical modeling/regression, machine learning, and other relevant data blending abilities.
You have experience in at least one of the following scripting languages: R, Python, MATLAB. Other languages such as SQL, Spark, and C++ are a bonus.
You have experience working in a Linux and/or cloud, shell scripting, and notebook environment.
You have knowledge of structured data, with the ability to perform data mapping for systems integration, data provisioning, and data consumption (strongly preferred).
You have a working knowledge of clinical trials (strongly preferred).

To be considered for this role, you must have a PhD, or Masters with minimum 2 years of relevant work experience in one of the following or otherwise related quantitative fields: Computer Science, Computational Biology, Systems Biology, Quantitative Biology, Bioinformatics, Data Analytics, Statistics, Biostatistics, Mathematics, Applied Mathematics, Physics, Chemistry.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries’ specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$108,300.00 - $176,700.00

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