Research Scientist

The Cellular Therapy Thematic Research Center is one of the fundamental research and early development engines delivering therapeutics to patients. Our mission is to drive leadership in the use of engineered cell-based therapies to harness the power of immune cells to mediate anti-tumor activity in hematology, solid cancers and in autoimmune diseases. Our thematic focus allows the group to capitalize on the cutting-edge science that underpins the action of many of the company?s most innovative therapeutics with the promise to delivering transformative medicine to patients.

Job Description

The Translational Biology team is looking for a creative and driven Associate Scientist/ Senior Associate Scientist to help advance our portfolio of cell therapies that have entered early clinical trials. Key responsibilities of this role are to develop non-clinical data packages for product mechanistic insights, potential combination therapies, identify new indications for our clinical stage assets and support manufacturing processes/platforms. The successful candidate will conduct laboratory-based experiments to contribute to mechanism of action and drug combination studies that would enable deeper durable responses for patients. The candidate must be familiar with mammalian cell culture and setting up in vitro functional assays to measure product functional attributes such as proliferation, cytokine production, phenotypic analysis, and cytotoxic activity. Prior experience with clinical samples, human T cells and/or evaluation of CAR-T is preferred. Flow cytometry experience is highly preferable. In addition, this position will work closely with senior researchers to execute studies, analyze data and communicate timely results. Highly team-oriented outlook and ability to prioritize multiple workstreams are a must. This position is ideal for an innovative, self-driven scientist who is forthcoming; willing to learn; and is passionate about cell therapy in a fast-paced, collaborative environment.

Primary Responsibilities

• Interrogation of primary human material; cell handling, setup, and maintenance of tissue culture studies
• CAR T cell phenotypic analysis using flow cytometry. In vitro functional evaluation using T cell/Tumor co-culture assays
• Cytotoxic activity using IncuCyte
• Cytokine assessments using MSD and intracellular cytokine production by flow cytometry
• Collaborating with scientists and other researchers to design, perform and optimize in vitro experiments
• Maintaining notebooks with detailed documentation of protocols, study designs and results
• Perform data analysis and interpretation
• Organize findings for effective communication to supervisor, colleagues as well as at external conferences
  
  

Basic Qualifications

• Associate Scientist: B.S. in biological science, immunology, or related discipline with 2 years of relevant academic and/or industry experience
• Senior Associate Scientist: B.S. in biological science, immunology, or related discipline with 4 years of relevant work experience or M.S. with 2 years of work experience
• 2 years of immunology laboratory experience with in-vitro cell-based assays
• Experience with primary cell culture
• Ability to analyze, interpret, and present scientific data in a clear manner
• Strong organization, time management and problem-solving skills with attention to detail
• Desire and ability to expand skill sets at the bench and knowledge base through independent reading and seeking out information from colleagues and project collaborators
  
  

Preferred Qualifications

• Working knowledge of clinical samples, human T-cells, and functional assays to evaluate CAR T cells
• Experience with high-parameter FACS (10-15 colors)
• Prior experience writing method development protocols
• Able to recognize potential problems and recommend/develop appropriate solutions
  
  

Level consideration will be determined based on prior experience.

100% Onsite!

Work Schedule- Standard Hours; M-F

This posting is for a contract assignment with ASK Staffing DBA ASK Consulting to provide services to Bristol Myer-Squibb .

The starting hourly compensation for this assignment is the following range ($50- $53.12/hr). While the final, individual compensation and any available benefits will be determined by your employer of record ASK Staffing, Inc (and not BMS), factors that will be included in making the final determination may include the characteristics of the assignment, such as demonstrated experience, required skill, and the geographic location where the job is performed. The starting hourly compensation may be subject to change.

About ASK Consulting

ASK Consulting is an award-winning, woman-owned staffing and recruitment solutions provider with over three decades of industry experience. We specialize in connecting businesses of all sizes?across IT, healthcare, engineering, finance, and more?with top-tier professionals. Backed by a global network and personalized service approach, our team is dedicated to building meaningful partnerships that drive organizational success and empower job seekers to excel in their careers.

Benefits

ASK Consulting provides comprehensive, ACA-compliant health coverage, along with dental, vision, Short- and Long-Term disability for eligible employees. We also offer commuter benefits, a 401(k) plan with no matching, and a referral bonus program. In addition, ASK Consulting offers unpaid leave and paid sick leave as required by law.

Equal Opportunity Employer

ASK Consulting is an equal opportunity employer and does not discriminate against employees or applicants based on race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability, veteran status, or any other classification protected by federal, state, or local laws.

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If you are selected for a position at, ASK Consulting, your offer is contingent upon successfully meeting several requirements, which may include a criminal background check. In accordance with all applicable federal, state, and local ?Fair Chance? ordinances and laws?such as the Los Angeles County Fair Chance Ordinance (FCO) and the California Fair Chance Act (FCA)?we consider qualified applicants with arrest or conviction records. The background check will evaluate whether any criminal history could reasonably pose a direct, negative impact on job-related safety, security, trust, regulatory compliance, or overall suitability for the role. Findings that raise concerns may result in withdrawal of a conditional job offer.

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This posting does not constitute an offer of employment. All applicants seeking positions in the United States must be legally authorized to work in the United States. Submitting intentionally false or fraudulent information in response to this posting may disqualify you from consideration. Any eventual offer of employment will be considered ?at will,? regardless of the expected assignment duration.