Sr. Research Associate 3 - Urology

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The University of Miami UHealth Department of Urology has an exciting opportunity for a full time Sr. Research Associate 3, SOM to work at the UHealth Medical Campus.

The Sr. Research Associate 3, SOM will perform research elucidating fundamental mechanisms of human biology with some relevance to prostate, kidney, or bladder cancer. The overarching goal of the institute’s research program is to define the underlying biochemical and clinical behavior of prostate, kidney, and bladder cancers in order to identify new strategies to prevent symptoms and death. Areas of interest include fundamental mechanisms biochemistry, metabolism and genetics.

The Sr. Research Associate 3, SOM supports the University’s research goals and objectives by engaging in complex experiments and investigations under the supervision of managing staff. Please submit a cover letter with your online application.

CORE JOB FUNCTIONS

• Contributes to basic and applied research activities by collecting and analyzing data.

• Understands and interprets research protocols and procedures.

• Maintains an overview of relevant research findings.

• Ensures all research is undertaken according to good research practice.

• Designs, evaluates, and implements methods and protocols for assigned research projects.

• Recommends purchase of new equipment for research projects.

• Writes scientific articles and manuscripts for publication and presentation.

• Oversees and ensures the safe handling of radioactive and hazardous materials.

• Prepares analytical reports relative to research data.

• Adheres to University and unit-level policies and procedures and safeguards University assets.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

CORE QUALIFICATIONS

Education:

• M.S. in biochemistry, chemistry, molecular biology or another relevant field required

• Minimum 3 years of relevant experience

Experience:
Minimum 3 years of relevant experience required

Knowledge, Skills and Attitudes:

• Has the appropriate expertise in discovery of molecular, biochemical or chemical mechanisms; and is highly driven.

• Outstanding verbal and communication skills are required.

• Skill in collecting, organizing, and analyzing data.

• Ability to recognize, analyze, and solve a variety of problems.

• Ability to exercise sound judgment in making critical decisions.

DEPARTMENT ADDENDUM

Department Specific Functions

Our laboratory focuses on mechanistic discovery to understand the metabolic and molecular mechanisms of androgen synthesis and androgen receptor gain-of-function that lead to resistance to hormonal therapy. Our work is revealing fundamental endocrine mechanisms in both normal physiology and disease, including stress, aging, and glucocorticoid resistance, that will lead to broad applications to oncology and cancer physiology.

Specific areas include:

• Metabolic and genetic changes required for hormone therapy resistance in prostate and breast cancers

• Discovery of entirely new mechanisms of endocrine physiology and regulation

• Clinical validation in patients and clinical trials using innovative approaches

• Animal models of advanced cancer for translational and therapeutic studies

• Identifying targets for the development of new pharmacologic therapies

• Drug discovery for new therapies

This position is ideal for an individual with a strong interest in rapid translation of basic mechanistic discoveries to the bedside as this is a principal goal of the Sharifi Laboratory. For example, we have shown that our discovery of a gain-of-function in a steroid-synthesizing enzyme is a predictive biomarker of poor outcomes after hormonal therapy (Hearn, et al. Lancet Oncol . 2016;17:1435-44; JAMA Oncol . 2018;4:558-62; JAMA Oncol . 2020;6(4):e196496). We are currently evaluating this biomarker in an active clinical trial and are pursuing similar mechanisms and developing new treatment modalities based on these discoveries.

The position will provide a unique and multidisciplinary exposure to tumor metabolism, molecular oncology, drug development, and clinical trials.

Knowledge, Skills and Abilities:

• Learning Agility: Ability to learn new procedures, technologies, and protocols, and adapt to changing priorities and work demands.

• Teamwork: Ability to work collaboratively with others and contribute to a team environment.

• Technical Proficiency: Skilled in using office software, technology, and relevant computer applications.

• Communication: Strong and clear written and verbal communication skills for interacting with colleagues and stakeholders.
  

This is a core job profile description and is not reflective of all duties that may be assigned to a specific position in each individual department. The above statements are intended to describe the general nature and primary responsibilities of this core job profile. Specific duties and tasks may vary based upon departmental needs. Other duties may be assigned to the above consistent with the knowledge, skills, and abilities required for the job.

#LI-FA

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information.

Job Status:

Full time

Employee Type:

Staff

Pay Grade:

A10