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research technician – fischer lab Jobs in Boston

research technician – fischer lab

bioinformatics scientist

molecular biology technician

Dana-Farber Cancer Institute

<div><div><div><div>Job Ref:</div><div>
JR-2269</div></div><br>
<div><div>Location:</div><div>
450 Brookline Ave, BOSTON, MA 02215</div><br>
</div>
<div><div>Category:</div><div>
Research Laboratory</div></div><br>
<div><div>Employment Type:</div><div>
Full time</div></div><br>
<div><div>Work Location:</div><div>
Onsite: 100% onsite</div></div><br>
<div></div><div><div>Salary/Pay Rate:</div><div>
$47,500.00 - $51,300.00 per year</div>
</div></div><p><b>Overview</b></p>
<p></p><div><div>The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology laboratory that combines a broad range of experimental and computational approaches to study protein homeostasis pathways and disease-relevant protein complexes, particularly those associated with cancer.<br>
Using deep expertise in cellular degradation machinery, we structure- and computation-guided strategies to develop and test novel small molecules that hijack the ubiquitin&ndash;proteasome system for targeted protein degradation. By integrating fundamental mechanistic insight with translational chemical biology, we are pioneering new therapeutic strategies with direct relevance to cancer treatment.<p>
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.</p><p><br>
The Fischer Lab (https://fischerlab.dana-farber.org/) seeks a highly motivated individual to join the team as a <b>Research Technician</b>. The successful candidate will work closely with a senior postdoctoral fellow to advance multiple ongoing research projects focused on pediatric cancer therapeutics. The successful candidate can develop an independent project if there is interest. The role is bench-intensive and central to the lab&rsquo;s scientific progress.</p><p>
In addition to experimental research, responsibilities include selected aspects of laboratory management and organization.</p><p>
A research technician will provide additional training and structured support during the transition period. Training is available across all major experimental platforms in the laboratory.</p><p>
This position offers the opportunity to contribute directly to innovative, therapeutically driven research in a highly collaborative environment with immediate translational impact in oncology.</p><p>
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.</p><p><br>
1. Responsible for technical assistance with multiple projects related to cancer therapeutics</p><p>
2. Performs protein expression and purification procedures</p><p>
3.Conduct standardized biological or biochemical assays and laboratory analyses, eg. TR-FRET, FP, pull downs, cell-based assays, western blot, flow cytometry 4. Analyzes experimental data and interpret results to write reports, presentations, grant and publication preparation</p><p>
5. Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.</p><p>
6. Maintains detailed notebook of all work-related activities</p><p>
7. Operation and maintenance of standard lab equipment</p><p>
8. Maintains and orders laboratory supplies</p><p>
9. Communicates with purchasing and may be responsible for negotiating with vendors</p><p>
10. Prepares lab reagents and media</p><p>
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:</p><p>
1. Knowledge of information and techniques related to biology and molecular biology</p><p>
2. Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff</p><p>
3. Ability to analyze information and use logic to address work-related issues and problems</p><p>
4. Must have attention to detail and be thorough in completing work tasks</p><p>
5. Ability to work within a team environment</p><p>
MINIMUM JOB QUALIFICATIONS:</p><p>
1. Bachelor's Degree required with a major in biology, chemistry or &ldquo;pre-med&rdquo; preferred.</p><p>
2. Master in biochemistry or related field preferred.</p><p>
3. Research experience in molecular biology or biochemistry</p><p>
4. Ability to analyze information and use logic to address work-related issues and problems.</p><p>
5. Must have close attention to detail and consistent work habits.</p><p>
6. Ability to work within a team environment.</p><p>
7. A minimum time commitment of 2 years is preferred.</p><p>
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to .</p><p>
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
</p><h3 class="jobSectionHeader"><b>EEO Poster</b></h3>
.<p>
Pay Transparency Statement</p><p>
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate&rsquo;s relevant experience, skills and qualifications.</p><p>
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).</p>
$47,500.00 - $51,300.00</div></div></div><p></p>

Research Technician – Fischer Lab

<div>
 The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology laboratory that combines a broad range of experimental and computational approaches to study protein homeostasis pathways and disease-relevant protein complexes, particularly those associated with cancer.
 <br/>
 <br/>
 Using deep expertise in cellular degradation machinery, we apply structure- and computation-guided strategies to develop and test novel small molecules that hijack the ubiquitin&ndash;proteasome system for targeted protein degradation. By integrating fundamental mechanistic insight with translational chemical biology, we are pioneering new therapeutic strategies with direct relevance to cancer treatment.
 <br/>
 <br/>
 Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
 <br/>
 <br/>
 The Fischer Lab (https://fischerlab.dana-farber.org/) seeks a highly motivated individual to join the team as a
 <strong>
  Research Technician
 </strong>
 . The successful candidate will work closely with a senior postdoctoral fellow to advance multiple ongoing research projects focused on pediatric cancer therapeutics. The successful candidate can develop an independent project if there is interest. The role is bench-intensive and central to the lab&rsquo;s scientific progress.
 <br/>
 <br/>
 In addition to experimental research, responsibilities include selected aspects of laboratory management and organization.
 <br/>
 <br/>
 A research technician will provide additional training and structured support during the transition period. Training is available across all major experimental platforms in the laboratory.
 <br/>
 <br/>
 This position offers the opportunity to contribute directly to innovative, therapeutically driven research in a highly collaborative environment with immediate translational impact in oncology.
 <br/>
 <br/>
 Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
 <br/>
 <br/>
 <ul>
  <li>
   Responsible for technical assistance with multiple projects related to cancer therapeutics
  </li>
  <li>
   Performs protein expression and purification procedures
  </li>
  <li>
   Conduct standardized biological or biochemical assays and laboratory analyses, eg. TR-FRET, FP, pull downs, cell-based assays, western blot, flow cytometry 4. Analyzes experimental data and interpret results to write reports, presentations, grant and publication preparation
  </li>
  <li>
   Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
  </li>
  <li>
   Maintains detailed notebook of all work-related activities
  </li>
  <li>
   Operation and maintenance of standard lab equipment
  </li>
  <li>
   Maintains and orders laboratory supplies
  </li>
  <li>
   Communicates with purchasing and may be responsible for negotiating with vendors
  </li>
  <li>
   Prepares lab reagents and media
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Knowledge, Skills, And Abilities Required
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Knowledge of information and techniques related to biology and molecular biology
  </li>
  <li>
   Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff
  </li>
  <li>
   Ability to analyze information and use logic to address work-related issues and problems
  </li>
  <li>
   Must have attention to detail and be thorough in completing work tasks
  </li>
  <li>
   Ability to work within a team environment
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Minimum Job Qualifications
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Bachelor's Degree required with a major in biology, chemistry or &ldquo;pre-med&rdquo; preferred.
  </li>
  <li>
   Master in biochemistry or related field preferred.
  </li>
  <li>
   Research experience in molecular biology or biochemistry
  </li>
  <li>
   Ability to analyze information and use logic to address work-related issues and problems.
  </li>
  <li>
   Must have close attention to detail and consistent work habits.
  </li>
  <li>
   Ability to work within a team environment.
  </li>
  <li>
   A minimum time commitment of 2 years is preferred.
   <br/>
   <br/>
  </li>
 </ul>
 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
 <br/>
 <br/>
 Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
 <br/>
 <br/>
 EEO Poster
 <br/>
 <br/>
 Pay Transparency Statement
 <br/>
 <br/>
 The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate&rsquo;s relevant experience, skills and qualifications.
 <br/>
 <br/>
 For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
 <br/>
 <br/>
 $47,500.00 - $51,300.00
</div>


Boston Children's Hospital

<div>
 Research Assistant Position (Agarwal Laboratory)
 <br/>
 <br/>
 General Summary
 <br/>
 <br/>
 The goal of Suneet Agarwal&rsquo;s team at BCH is to understand and treat fatal genetic blood disorders. We study these diseases by &ldquo;turning back the clock&rdquo; &ndash; using new technology in stem cell biology to take cells from our patients and return them to an embryonic-like state, wherein they regain the ability to form any type of cell in the body. The knowledge gained through our work is providing new insights into disease mechanisms and innovative treatment strategies for our patients, including novel small molecules, RNA therapeutics, and genome-editing approaches. The genetic blood diseases we study are the tip of the iceberg for several other telomere biology diseases and mitochondrial disorders of children and adults, and therefore we expect our work to provide answers for a broader number of people with fatal diseases.
 <br/>
 <br/>
 The position offers an exciting opportunity to work closely with basic and translational scientists in a highly collaborative and stimulating environment in the Division of Hematology/Oncology at BCH. This is an excellent opportunity for future scientists / physician-scientists who aim to further our fundamental understanding of molecular biology, and see these advances applied to human diseases.
 <br/>
 <br/>
 <strong>
  This position has a June 2026 start date.
  <br/>
  <br/>
 </strong>
 <strong>
  Key Responsibilities
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   According to prescribed protocols and assigned schedules, performs a variety of routine laboratory experiments and procedures, utilizing standard laboratory equipment, recording and checking results for completeness and accuracy.
  </li>
  <li>
   Assists in troubleshooting procedures if experimental results are unexpected or quality of specimens is poor. Performs the following techniques typically required for the laboratory/study: Maintains records of results and methodologies in a log of work performed.
  </li>
  <li>
   Maintains equipment, lab area, and supplies in a neat professional manner. Sterilize and clean glassware and prepare media and other materials using appropriate procedures. Inventories supplies, alerts supervisor to needed supplies, or mixes standard reagents.
  </li>
  <li>
   Processes order for supplies and/or animals. Attends courses in safety procedures for handling, storage, and disposal of biohazardous, flammable, corrosive, and toxic materials.
  </li>
  <li>
   Carries out all laboratory activities in compliance with applicable regulations and protocols. Conducts literature searches and reviews, compiling information for journals and suggesting uses for new techniques to the P.I.
  </li>
  <li>
   Attend courses, lectures, and conferences to further own knowledge of research and laboratory techniques, consult with other researchers and technicians to exchange information. Contributes to the team within and between departments and organizations.
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Requirements
  <br/>
  <br/>
 </strong>
 <strong>
  Education
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Applicants must have completed a Bachelor&rsquo;s or Master&rsquo;s degree in the biological or physical sciences.
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Experience
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Technical knowledge and prior experience in molecular biology and cell culture techniques is preferred.
  </li>
  <li>
   The ideal applicant will be a meticulous and self-driven individual, committed to learning and working to contribute to advances in biology and medicine.
  </li>
  <li>
   He or she will demonstrate exceptional organizational and communication skills and be able to prioritize multiple tasks.
  </li>
  <li>
   A two-year commitment is required.
   <br/>
   <br/>
  </li>
 </ul>
 The posted pay range is Boston Children&rsquo;s reasonable and good-faith expectation for this pay at the time of posting.
 <br/>
 <br/>
 Any base pay offer provided depends on skills, experience, education, certifications, and a variety of other job-related factors. Base pay is one part of a comprehensive benefits package that includes flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.
</div>


Research Assistant I-Agarwal Lab

Harvard Medical School

<div>
 <strong>
  Company Description
  <br/>
  <br/>
 </strong>
 By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive.
 <br/>
 <br/>
 <strong>
  Why join Harvard Medical School?
  <br/>
  <br/>
 </strong>
 Harvard Medical School's mission is to nurture a diverse, inclusive community dedicated to alleviating suffering and improving health and well-being for all through excellence in teaching and learning, discovery and scholarship, and service and leadership.
 <br/>
 <br/>
 You&rsquo;ll be at the heart of biomedical discovery, education, and innovation, working alongside world-renowned faculty and a community dedicated to improving human health. This is more than a job - it&rsquo;s an opportunity to shape the future of medicine.
 <br/>
 <br/>
 <strong>
  Job Description
  <br/>
  <br/>
 </strong>
 The Walter Laboratory (https://walter.hms.harvard.edu/) at Harvard Medical School and the Howard Hughes Medical Institute in Boston is seeking a highly motivated Research Assistant to study genome maintenance and how defects in this process cause cancer and other human diseases. The laboratory uses a powerful biochemical system derived from frog eggs as a model to study mechanisms of DNA replication and DNA repair. We use molecular biology, biochemistry, cell biology, and single-molecule imaging approaches. The Walter lab is a welcoming community where all members actively work together to understand how cells maintain their genomes in health and disease.
 <br/>
 <br/>
 Under supervision from a post-doctoral fellow or graduate student, the Research Assistant will pursue a project involving a wide range of techniques, including setting up in-vitro biochemical reactions using frog egg extracts, electrophoresis, microscopy, Western blotting, and molecular cloning. In conducting their research, technicians will design, carry out, interpret, record, and present experiments.
 <br/>
 <br/>
 Our technicians are encouraged to take intellectual ownership of their projects. They present at lab meetings and journal clubs, contribute to manuscripts, and sometimes attend scientific conferences. ~70% of time will be dedicated to research, with the remaining time spent on activities that support the entire laboratory (see below). Working in the Walter laboratory is excellent preparation for graduate and medical school. Former technicians from the laboratory have been accepted to top Ph.D., M.D./Ph.D., and M.D. programs.
 <br/>
 <br/>
 Harvard Medical School and the surrounding hospitals bring together world-renowned scientists and clinicians in a community dedicated to understanding the marvels of human biology and conquering disease. With regular symposia, daily seminars, and several large graduate programs, Harvard Medical School allows young trainees to realize their career goals and reach their full potential as scientists.
 <br/>
 <br/>
 <strong>
  Responsibilities
  <br/>
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Carry out a scientific project under the direction of a postdoctoral fellow or Ph.D. candidate. Design, execute, interpret, record, and present experiments. Participate actively in the scope and direction of research projects.
  </li>
  <li>
   Read and interpret literature applicable to research areas.
  </li>
  <li>
   Use software applications to interpret and present data.
  </li>
  <li>
   Participate actively in the scope and direction of research projects.
  </li>
  <li>
   Manage day-to-day to day activity and organization within the laboratory.
  </li>
  <li>
   Order chemicals, reagents, and other laboratory supplies.
  </li>
  <li>
   Renew and amend lab permits.
  </li>
  <li>
   Maintain laboratory equipment.
  </li>
  <li>
   Maintain laboratory website.
  </li>
  <li>
   Serve as laboratory safety and radiation safety representative.
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Qualifications
  <br/>
  <br/>
 </strong>
 <strong>
  Basic Qualifications:
  <br/>
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   College background or equivalent work experience, preferably in Biochemistry, Molecular or Cell Biology, Chemistry, or related discipline.
  </li>
  <li>
   At least one year of related work experience (relevant course work may count towards experience).
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Additional Qualifications and Skills:
  <br/>
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Some prior Molecular Biology experience (including coursework) is highly preferred.
  </li>
  <li>
   Actively seeks opportunities to increase skills and expertise.
  </li>
  <li>
   Able to learn complex tasks with instruction.
  </li>
  <li>
   Able to learn and perform a variety of new techniques.
   <br/>
   <br/>
  </li>
 </ul>
 Additional Information
 <br/>
 <br/>
 <br/>
 <ul>
  <li>
   Appointment End Date: This is a six-month term position from the date of hire, with the possibility of extension, contingent upon work performance and continued funding to support the position.
  </li>
  <li>
   Standard Hours/Schedule: 40 hrs. per week | Monday - Friday | 8:00 am - 5:00 pm
  </li>
  <li>
   Visa Sponsorship Information: Harvard University is unable to provide visa sponsorship for this position.
  </li>
  <li>
   Pre-Employment Screening: Identity, Criminal, Pre-Placement Medical
  </li>
  <li>
   Other Information: Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.
  </li>
  <li>
   Staying Informed About Your Application: Due to the high volume of applications, we may not always be able to reach out right away, but you can track your status anytime through the Careers@Harvard portal.
   <br/>
   <br/>
  </li>
 </ul>
 <strong>
  Work Format Details
  <br/>
  <br/>
 </strong>
 This position has been determined by school or unit leaders that all duties and responsibilities must be performed at a Harvard or Harvard-designated location. Certain visa types may limit work location. Individuals must meet work location sponsorship requirements prior to employment.
 <br/>
 <br/>
 <strong>
  Salary Grade and Ranges
  <br/>
  <br/>
 </strong>
 This position is salary grade level 052. Please visit  Harvard's Salary Ranges  to view the corresponding salary range and related information.
 <br/>
 <br/>
 <strong>
  Benefits
  <br/>
  <br/>
 </strong>
 Harvard offers a comprehensive benefits package that is designed to support a healthy work-life balance and your physical, mental and financial wellbeing. Because here, you are what matters. Our benefits include, but are not limited to:
 <br/>
 <br/>
 <br/>
 <ul>
  <li>
   Generous paid time off including parental leave
  </li>
  <li>
   Medical, dental, and vision health insurance coverage starting on day one
  </li>
  <li>
   Retirement plans with university contributions
  </li>
  <li>
   Wellbeing and mental health resources
  </li>
  <li>
   Support for families and caregivers
  </li>
  <li>
   Professional development opportunities including tuition assistance and reimbursement
  </li>
  <li>
   Commuter benefits, discounts and campus perks
   <br/>
   <br/>
  </li>
 </ul>
 Learn more about these and additional benefits on our Benefits &amp; Wellbeing Page.
 <br/>
 <br/>
 <strong>
  EEO/Non-Discrimination Commitment Statement
  <br/>
  <br/>
 </strong>
 Harvard University is committed to equal opportunity and non-discrimination. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard's academic purposes.
 <br/>
 <br/>
 Harvard has an equal employment opportunity policy that outlines our commitment to prohibiting discrimination on the basis of race, ethnicity, color, national origin, sex, sexual orientation, gender identity, veteran status, religion, disability, or any other characteristic protected by law or identified in the university's non-discrimination policy. Harvard's equal employment opportunity policy and non-discrimination policy help all community members participate fully in work and campus life free from harassment and discrimination.
 <br/>
 <br/>
</div>


Research Assistant I Lab

The General Hospital Corporation

<div>Site: The General Hospital Corporation<p></p><p><br>
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.</p><br>
<p></p>
Cardiac arrest, atherosclerosis, myocardial infarction, and stroke affect more than 40 million people in the United States and cardiovascular disease is the number one cause of morbidity and mortality globally. Our laboratories are interested in understanding the underlying molecular mechanisms that contribute to the development of cardiovascular disease. Through these mechanistic studies we hope to identify novel therapeutic targets to treat and prevent heart disease. We carry out experiments both in vitro and in vivo using multiple different cell-based assays and mouse models to understand the roles that specific proteins have in vascular disease and cardiac arrest. This position will require the handling of mice and carrying out relevant procedures on mice. Common techniques include RNA isolation, cDNA synthesis, qPCR, Western blots and protein isolation, sterile tissue culture, genotyping, mouse dissection, and echocardiography. The research technician will be involved in all aspects of the research process from designing and executing experiments, to analyzing and presenting data, to writing the final research papers.
<br>
<br>
This position is ideally targeted towards a candidate interested in pursuing a career in academic medicine or biomedical research, but all that are interested are encouraged to apply. Our laboratories have mentored numerous students as they transition to either medical school or graduate school.<p></p><p><b><br>
Job Summary</b></p>
Summary<br>
Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.
<br>
<br>
Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.<br>
<br>
Does this position require Patient Care?<br>
No<br>
<br>
Essential Functions<br>
<ul><li>Perform laboratory experiments following established protocols and procedures.
</li><li>Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
</li><li>Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
</li><li>Record experimental data accurately and maintain organized records of procedures, protocols, and results.
</li><li>Compile and analyze data using appropriate statistical and analytical methods.
</li><li>Assist in data interpretation and presentation, contributing to research findings and reports.</li></ul><p></p><div><div><div><div><div><div><div><p><b><br>
Qualifications</b></p></div></div></div></div></div></div></div><p>
Education<br>
Bachelor's Degree Related Field of Study required<br>
<br>
Can this role accept experience in lieu of a degree?<br>
Yes<br>
<br>
Licenses and Credentials<br>
<br>
Experience<br>
Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred<br>
Prior molecular biology lab experience is strongly recommended, but not required</p><div><br>
Knowledge, Skills and Abilities<br>
<ul><li>Strong theoretical and practical knowledge of laboratory techniques and procedures.</li><li>Familiarity with common laboratory equipment and instruments used in research experiments.</li><li>Proficiency in data collection, analysis, and scientific software tools.</li><li>Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.</li><li>Strong problem-solving skills and the ability to troubleshoot technical issues.</li><li>Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.</li></ul></div><p></p><div><div><div><div><div><div><div><p><b><br>
Additional Job Details (if applicable)</b></p></div></div></div></div></div></div></div><p></p><div><div><div><div><div><div><div><p><b><br>
Remote Type</b></p></div></div></div></div></div></div></div>
Onsite<p></p><div><div><div><div><div><div><div><p><b><br>
Work Location</b></p></div></div></div></div></div></div></div>
55 Fruit Street<p></p><div><div><div><div><div><div><div><p><b><br>
Scheduled Weekly Hours</b></p></div></div></div></div></div></div></div>
40<p></p><div><div><div><div><div><div><div><p><b><br>
Employee Type</b></p></div></div></div></div></div></div></div>
Regular<p></p><div><div><div><div><div><div><div><p><b><br>
Work Shift</b></p></div></div></div></div></div></div></div>
Day (United States of America)<p></p><p><b><br>
Pay Range</b></p>
$20.16 - $29.01/Hourly<p></p><p><b><br>
Grade</b></p>
5<br>
<p></p>
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.<p></p><div><div><div><div><div><div><div><p><b><br>
EEO Statement:</b></p></div></div></div></div></div></div></div>
1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran&rsquo;s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.<p></p><h2 class="jobSectionHeader"><b><br>
Mass General Brigham Competency Framework</b></h2><div><div><p>
At Mass General Brigham, our competency framework defines what effective leadership &ldquo;looks like&rdquo; by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.</p></div></div></div>

Research Technician

Boston University

<div><p>Our laboratory invites applications for a postdoctoral associate focused on defining the molecular and cellular mechanisms by which bacterial infections drive lymphatic vessel dysfunction and lymphedema progression.</p>
<p>
The successful candidate will contribute to a multidisciplinary project employing the following methods:</p>
<div>
<ul><li>Characterization of molecular and cellular perturbations caused by S. aureus strains using single-cell transcriptomics and lineage tracing in murine models of cutaneous infection and lymphatic vessel dysfunction.</li></ul>
<ul><li>Delineation of infection-associated signaling cascades and testing the efficacy of pharmacological agents to restore contractile function of lymphatic vessels.</li></ul>
<ul><li>Evaluation of the impact of S. aureus toxins on lymphatic vessel dynamics through high-resolution functional imaging.</li></ul>
<ul><li>Investigation of targeted inhibition of S. aureus toxins on lymphatic function and host antimicrobial immunity in vivo to determine protective potential against recurrent infections.</li></ul>
</div>
<p>Responsibilities</p>
<p>
The postdoctoral associate will spend at least 80% of their time on research activities, including:</p>
<div>
<ul><li>Design and execution of murine infection models and assessment of lymphatic vessel function.</li></ul>
<ul><li>Performance of single-cell RNA sequencing, lineage tracing, and high-resolution calcium imaging experiments.</li></ul>
<ul><li>Analysis and interpretation of transcriptomic, imaging, and functional data.</li></ul>
<ul><li>Testing pharmacological interventions and bacterial toxin inhibitors in vivo.</li></ul>
<ul><li>Collaboration with clinical and translational research teams.</li></ul>
<ul><li>Co-authoring manuscripts, presenting findings at scientific conferences, and contributing to grant preparation.</li></ul>
</div>
<p>The remaining 20% may include:</p>
<div>
<ul><li>Mentoring graduate students and research assistants.</li></ul>
<ul><li>Participating in laboratory meetings, journal clubs, and institutional seminars.</li></ul>
<ul><li>Contributing to manuscript and grant writing efforts.</li></ul>
</div>
<p>Appointment Details</p>
<p>
Duration: Three years, with possibility of extension based on performance and funding<br>
Salary: $70K</p><br>
<br>
<br>
Required Skills<br>
<p>We seek candidates with expertise in vascular biology, immunology, microbiology, or related fields. Strong background in one or more of the following areas is required:</p>
<ul>
<li>Experience with murine infection models, particularly cutaneous or soft tissue infection models.</li>
<li>Proficiency in functional imaging techniques such as intravital imaging</li>
<li>Familiarity with single-cell RNA sequencing, bioinformatics analysis, or lineage tracing approaches.</li>
<li>Experience with vessel isolation, ex vivo functional assays, or vascular smooth muscle cell biology.</li>
</ul>
<p>Candidates with expertise in bacterial pathogenesis, toxin biology, host-pathogen interactions, or pharmacological intervention studies are especially encouraged to apply. The ideal candidate will be comfortable working at the interface of microbiology, vascular biology, and immunology and conducting hypothesis-driven research with translational implications.</p><br>
<p></p>
<p><b>
APPLICATION INSTRUCTIONS:</b></p>
<p>
Email a Curriculum Vitae and a cover letter explaining your research interests to Dennis Jones, PhD, djones1@bu.edu.</p><br>
<p></p>
<p><i>
We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, natural or protective hairstyle, religion, sex, age, national origin, physical or mental disability, sexual orientation, gender identity, genetic information, military service, pregnancy or pregnancy-related condition, or because of marital, parental, or veteran status. We are a VEVRAA Federal Contractor.</i></p></div>

Postdoctoral Associate, Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine

Brigham and Women's Hospital

<div>
 Site: The Brigham and Women's Hospital, Inc.
 <br/>
 <br/>
 Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
 <br/>
 <br/>
 <strong>
  Overview
  <br/>
  <br/>
 </strong>
 <strong>
  Job Summary
  <br/>
  <br/>
 </strong>
 In the Nakashima Lab at the Harvey Cushing Neuro-Oncology Laboratories, within the Department of Neurosurgery at Brigham and Women's Hospital, our research is focused on the developmental immunotherapy with tumor-permissive oncolytic viruses and tumor immune mechanisms governing highly immune tolerance and resistance in brain tumors. We use advanced DNA manipulation and animal models in conjunction with the latest molecular and immunological tools in our investigation of brain tumor and immunity. We are looking for an energetic and highly organized research assistant interested in various biological and immunological experiments, including plasmid DNA, RNA, genome extraction, (RT-)PCR, Western blot, immunohistochemistry, flow cytometry, virus, cell culture, and other essential molecular biological experiments.
 <br/>
 <br/>
 <strong>
  Qualifications
  <br/>
  <br/>
 </strong>
 Description:
 <br/>
 <br/>
 With general supervision by the Principal Investigator, Research Fellow and Lab Manger, the Research Lab Technician will be expected to carry out designated experiments. As this research involves using murine models, the Research Lab Technician may need to assist in animal care and experiments, including transgenic colony maintenance, imaging, and health check (weekly body weight, post-surgery care). Other duties may include writing laboratory SOP, preparing various regulatory protocols such as IACUC and IBC, and data formatting with Excel, R, and other bioinformatic approaches.
 <br/>
 <br/>
 <strong>
  Requirements
  <br/>
  <br/>
 </strong>
 <ul>
  <li>
   Bachelor&rsquo;s degree in biology, veterinary, neuroscience, immunology, or related field.
  </li>
  <li>
   Basic knowledge and experience with techniques of cell culture, tissue processing, molecular biology, chemistry, small animal handling and colony management skills a plus.
  </li>
  <li>
   Good laboratory practices, well organized in planning and performing lab work, maintaining good lab records and electronic notebooks are necessary.
  </li>
  <li>
   Strong motivation for curiosity-driven research, hypothesis-generation, and constant desire to improve on scientific technologies.
  </li>
  <li>
   Additional experience working in research labs or animal facilities that handle mice experience helpful; Experience with biological and immunological laboratory techniques including DNA cloning into vectors, virus propagation and titration, processing methods and analysis of DNA/RNA/protein from cells, tissues and mice, tissue culture, operations of fluorescent microscopy, flow cytometry, PCR machines, and/or ultra-centrifugation is a plus.
  </li>
  <li>
   Excellent oral and written communication skills. Ability to communicate effectively with a diverse team of researchers.
  </li>
  <li>
   Ability to make at least 1-year commitment to the position to contribute technically to newly funded NIH grant studies. Longer term contribution of more than 1 year is welcomed.
   <br/>
   <br/>
  </li>
 </ul>
 As a part of the research team, your duties and responsibilities would include:
 <br/>
 <br/>
 <ul>
  <li>
   Working with Dr. Nakashima and team to conduct research projects
  </li>
  <li>
   Contributing technically to the existing funded NIH grant studies and collect data for submission of the NIH grant proposal.
  </li>
  <li>
   Assisting with mouse studies, including colony maintenance, health monitoring, and in vivo imaging and post-surgery monitoring
  </li>
  <li>
   Maintaining biological material resources
  </li>
  <li>
   Documenting all research activities using a digital notebook (LabArchives)
  </li>
  <li>
   Making pre-experiment lab preparations (e.g., autoclave, reagent preparation, etc.)
  </li>
  <li>
   Attendance at all lab meetings
  </li>
  <li>
   Maintaining lab equipment
   <br/>
   <br/>
  </li>
 </ul>
 NOTE: This position is grant funded. Due to the nature of experimental protocols, some off-hours work may occasionally be required.
 <br/>
 <br/>
 <strong>
  Additional Job Details (if Applicable)
  <br/>
  <br/>
 </strong>
 <strong>
  Remote Type
  <br/>
  <br/>
 </strong>
 Onsite
 <br/>
 <br/>
 <strong>
  Work Location
  <br/>
  <br/>
 </strong>
 60 Fenwood Road
 <br/>
 <br/>
 <strong>
  Scheduled Weekly Hours
  <br/>
  <br/>
 </strong>
 40
 <br/>
 <br/>
 <strong>
  Employee Type
  <br/>
  <br/>
 </strong>
 Regular
 <br/>
 <br/>
 <strong>
  Work Shift
  <br/>
  <br/>
 </strong>
 Day (United States of America)
 <br/>
 <br/>
 <strong>
  Pay Range
  <br/>
  <br/>
 </strong>
 $20.16 - $29.01/Hourly
 <br/>
 <br/>
 <strong>
  Grade
  <br/>
  <br/>
 </strong>
 5
 <br/>
 <br/>
 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
 <br/>
 <br/>
 <strong>
  EEO Statement
  <br/>
  <br/>
 </strong>
 2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran&rsquo;s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
 <br/>
 <br/>
 <strong>
  Mass General Brigham Competency Framework
  <br/>
  <br/>
 </strong>
 At Mass General Brigham, our competency framework defines what effective leadership &ldquo;looks like&rdquo; by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
</div>


Research Lab Technician I

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Research Lab Technician I