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ai/ml engineer

ai engineer assistant

Build.inc

<div>
 
 About Build
 
 
 
 AI for the Built World: Build has created the agentic AI stack for institutional real estate, automating complex development and acquisitions workflows 90% faster than humans to accelerate the world&rsquo;s most important built projects - digital infrastructure, energy, industrial - from concept to completion.
 
 
 Our mission is to accelerate and amplify the world's most important built projects - inventing a better way to build through a collaboration between human experts and agentic AI. We envision a future where the world's buildings are driven from concept to completion, autonomously. Without delays, cost, and complexity. Enabling people to deliver a magnitude more deals. To make decisions, build relationships and create.
 
 
 To start, we're partnering with the world's biggest built world institutions from $T alternative assets investors, prolific developers and even governments to push the frontier of what's possible. We&rsquo;re backed by c-suite from Blackstone and OpenAI alongside the world&rsquo;s best venture capital firms.
 
 
 Join us in shaping the future of the Built World and exponentially accelerate your career in the process. We welcome you to do your life's work here.
 
 
 
 About The Role
 
 
 
 This role sits at the intersection of product, infrastructure, and user experience. You will turn the Build Assistant, Dougie, into a world-class product: turning the world&rsquo;s best geospatial data and tooling layer into something usable, powerful, and trusted by institutions. Strong product sensibility is not optional; the ability to execute on it is a force multiplier.
 
 
 You&rsquo;ll work closely with James SE and Ben McClusky.
 
 
 
 You can expect to:
 
 
 
 <ul>
 <li>
 Design, build, and deploy the Build Assistant: an AI-native product that sits on top of complex geospatial data, models, and workflows, and makes them usable through a single coherent interface.
 </li>
 <li>
 Build a non-deterministic, multi-agent orchestration layer that coordinates tools, data sources, and human input to deliver reliable outcomes in ambiguous, real-world scenarios.
 </li>
 <li>
 Translate institutional real estate and infrastructure workflows into a clean ontology that agents and humans can operate against.
 </li>
 <li>
 Own and ship full-stack features end-to-end, from agent behavior and orchestration to UI, performance, and production reliability.
 </li>
 <li>
 Build beautiful, opinionated user interfaces on top of Build&rsquo;s design systems, where clarity, speed, and trust matter more than novelty.
 </li>
 <li>
 Work directly with domain experts and customers to pressure-test assumptions and ensure the assistant delivers real leverage, not demos.
 </li>
 <li>
 Solve unsolved problems at the intersection of AI systems and the physical world, where correctness, explainability, and failure modes matter.
 </li>
 <li>
 Build software that scales in both usage and complexity, with a bias toward robustness, observability, and long-term maintainability.
 
 
 </li>
 </ul>
 
 
 How to win at Build
 
 
 
 
 Growing Build requires a radically different approach to company building. As a company we&rsquo;re focused on one outcome: winning. That means we move fast, work with intensity, and demand excellence from ourselves. We operate with intensity but create an environment that allows for a lot of fun together. The result is that we're one of the fastest shipping teams in vertical AI, partnering with the best to automate the world around us.
 
 
 
 Performance
 
 and
 
 teamwork
 
 are the core of Build&rsquo;s operation. We look for those who are able to do both, who often exhibit a particular ability for;
 
 
 <ul>
 <li>
 Velocity: You are relentless in asking the right questions to set direction. Once you find the right direction you go all-in.
 </li>
 <li>
 Excellence: You obsess with being the best. For you, excellence is a non-negotiable standard rather than an aspiration.
 </li>
 <li>
 Long time horizons: You choose to be in something for the long run, because that&rsquo;s where most of the returns are realized.
 </li>
 <li>
 Ownership: You take full ownership of the outcomes. You&rsquo;re meticulous in your pursuits and believe you can actively shape your environment rather than adapt to it.
 </li>
 <li>
 Customers: You have a passion for the built world and those who shape it. You probably have a quirky hobby or story that relates to your love for building.
 </li>
 <li>
 Integrity: You chose to do the right thing even when it isn&rsquo;t easy.
 </li>
 <li>
 Trust: You only work with people you can trust because it&rsquo;s the only way to do truly extraordinary things.
 </li>
 <li>
 Yield: You have a burning need to see a result on every action you take and you&rsquo;re always looking for routes to do more with less.
 
 
 </li>
 </ul>
 
 
 What we offer
 
 
 
 
 <ul>
 <li>
 Radical autonomy, real ownership: High standards. Minimal bureaucracy. You own problems end-to-end, choose how the work gets done, and are accountable for exceptional outcomes. Ownership is matched with meaningful, generous equity.
 </li>
 <li>
 An accelerated founder&rsquo;s track: Build is for builders. If you want to learn what it actually takes to create a generational company &ndash; Product judgment, execution speed, and accountability &ndash; there is no faster path than building from zero when everything is for grabs.
 </li>
 <li>
 Elite teammates, uncompromising bar: You work with people who think clearly, execute relentlessly, and take full ownership. The team you build becomes the company you build. Growth here is not just professional; it reshapes how you operate and in return how Build operates.
 </li>
 <li>
 Perpetual adventure: We attract the strongest of the strange. Extraordinary experiences are part of the culture - from the food we eat together to the space we occupy. Intensity is intentional.
 </li>
 <li>
 Shape the built world: We are rebuilding how the physical world gets made. Our software doesn&rsquo;t live in the abstract - it turns into real projects breaking ground because we exist. We work with the largest institutions, push the frontier of AI, and watch our decisions translate directly into the world around us.
 
 
 </li>
 </ul>
 Compensation Range: $130K - $185K
 
 
</div>

AI Engineer (Assistant)

Call For Referral

<div>
 
 
 Machine Learning Engineer
 
 
 
 
 Work Mode:
 
 
 Remote
 
 
 
 
 Compensation:
 
 
 $100&ndash;$120 per hour
 
 
 
 
 Work Type:
 
 
 Hourly, Independent
 
 
 
 
 Role Overview
 
 
 
 This role supports the evaluation of
 
 advanced machine learning systems
 
 in collaboration with
 
 leading AI research initiatives
 
 . It is intended for
 
 experienced machine learning engineers and researchers
 
 who can contribute to the development of
 
 high-quality evaluation suites
 
 that measure AI performance on
 
 real-world machine learning engineering tasks
 
 .
 
 
 The work focuses on translating
 
 practical ML research and engineering workflows
 
 into
 
 structured benchmarks
 
 for
 
 frontier models
 
 . This is a
 
 project-based, fully remote
 
 opportunity for professionals with
 
 strong hands-on ML research and engineering experience
 
 .
 
 
 
 Key Responsibilities
 
 
 <ul>
 <li>
 
 Design and develop
 
 detailed evaluation suites for machine learning engineering tasks
 </li>
 <li>
 
 Evaluate AI-generated solutions
 
 across model training, debugging, optimization, and experimentation workflows
 </li>
 <li>
 
 Analyze and document
 
 system behavior, performance characteristics, and limitations
 </li>
 <li>
 
 Contribute to the creation of benchmarks
 
 that reflect real-world ML engineering practices
 </li>
 <li>
 
 Maintain high standards
 
 of technical accuracy, clarity, and consistency in all deliverables
 </li>
 </ul>
 
 
 Qualifications
 
 
 <ul>
 <li>
 
 3+ years
 
 of experience in machine learning engineering or applied ML research
 </li>
 <li>
 
 Hands-on experience
 
 with model development, experimentation, and evaluation
 </li>
 <li>
 
 Background in ML research
 
 in an industry or academic setting (strongly preferred)
 </li>
 <li>
 
 Strong ability
 
 to reason about ML system design choices and technical trade-offs
 </li>
 <li>
 
 Excellent written communication skills
 
 and
 
 high attention to technical detail
 
 </li>
 </ul>
 
 
 Work &amp; Payment Details
 
 
 <ul>
 <li>
 You will operate as an
 
 independent professional
 
 </li>
 <li>
 This is a
 
 fully remote
 
 role with a
 
 flexible schedule
 
 </li>
 <li>
 Projects may be
 
 extended, shortened, or concluded
 
 based on needs and performance
 </li>
 <li>
 The work does
 
 not involve access to confidential or proprietary information
 
 from any employer, client, or institution
 </li>
 <li>
 
 Payments are made weekly
 
 via
 
 Stripe or Wise
 
 , based on services delivered
 </li>
 <li>
 Candidates requiring
 
 H1-B or STEM OPT
 
 sponsorship are
 
 not supported
 
 at this time
 </li>
 </ul>
 
 
 Application &amp; Onboarding Process
 
 
 <ul>
 <li>
 
 Upload your resume
 
 </li>
 <li>
 
 AI interview:
 
 A short
 
 15-minute
 
 conversational session to understand your background, experience, and interest in the role
 </li>
 <li>
 
 Follow-up communication
 
 within a few days with next steps and onboarding details
 </li>
 </ul>
 
 
</div>

Machine Learning Engineer (Remote)  $100 –$120/hr

Arcade

<div>
 
 About Arcade
 
 
 
 Arcade is building the world&rsquo;s first AI physical product creation platform, where imagination becomes reality. Our platform lets anyone design, purchase, and sell custom, manufacturable products using natural language and generative AI. We believe everyone should have the power to create physical goods as easily as they post online, and we&rsquo;re building the infrastructure to make that real.
 
 
 We&rsquo;ve raised $42M from a world-class group of investors, including Reid Hoffman, Forerunner Ventures (Kirsten Green), Canaan Partners (Laura Chau), Adverb Ventures (April Underwood), Factorial Funds (Sol Bier), Offline Ventures (Brit Morin), Sound Ventures (Ashton Kutcher), Inspired Capital (Alexa von Tobel), and Torch Capital (Jonathan Keidan). Our angel investors include Elad Gil, Ev Williams, Marissa Mayer, Sara Beykpour, Kayvon Beykpour, Anna Veronika Dorogush, Eugenia Kuyda, David Luan, Sharon Zhou, Kelly Wearstler, Karlie Kloss, Colin Kaepernick, Christy Turlington Burns, and Jeff Wilke.
 
 
 Arcade is headquartered in San Francisco&rsquo;s Presidio and led by serial entrepreneur Mariam Naficy (Minted, Eve), and a founding team with deep experience in generative AI, design systems, and supply chain. We&rsquo;re pioneering a new category at the intersection of AI, personal expression, and on-demand manufacturing, and we&rsquo;re building fast.
 
 
 
 Overview Of Role
 
 
 
 We are seeking an Applied AI Engineer to join our growing team and help advance our generative AI capabilities. This role blends hands-on model development with integration of cutting-edge AI techniques into production systems. You&rsquo;ll contribute to research, model experimentation, and implementation working closely with cross-functional teams to bring AI-driven products to life.
 
 
 
 Responsibilities
 
 
 
 <ul>
 <li>
 Collaborate with engineering and product teams to train and fine-tune machine learning models, including diffusion models, LLMs, and other emerging generative architectures
 </li>
 <li>
 Develop tools and pipelines that support scalable, efficient, and production-ready AI systems
 </li>
 <li>
 Collect, clean, and analyze large-scale datasets to improve model performance and reliability
 </li>
 <li>
 Deploy and maintain AI models in production environments, ensuring scalability, reliability, and efficiency
 </li>
 <li>
 Design and deploy text-to-image models and LLM-based applications, including advanced prompt engineering, fine-tuning, and multi-component workflows
 </li>
 <li>
 Maintain and monitor deployed models in cloud-based production environments
 </li>
 <li>
 Stay current with developments in generative AI, contribute to the research environment, and apply new developments to enhance pipeline performance
 </li>
 <li>
 Communicate technical concepts clearly across technical and non-technical audiences
 
 
 </li>
 </ul>
 
 Qualifications
 
 
 
 <ul>
 <li>
 Bachelor&rsquo;s or Master&rsquo;s degree in Computer Science, Mathematics, AI/ML, or a related field
 </li>
 <li>
 Strong proficiency in Python and familiarity with Linux environments; hands-on experience with machine learning libraries like PyTorch, TensorFlow,, etc.
 </li>
 <li>
 Strong fundamentals in machine learning concepts, with a deep understanding of algorithms and their underlying mechanics ("under the hood")
 </li>
 <li>
 Familiarity with training, fine-tuning, and evaluating models, especially with large-scale datasets
 </li>
 <li>
 Familiarity with data preprocessing, cleaning, and feature engineering
 </li>
 <li>
 Awareness of recent developments in generative AI, diffusion models, and LLMs
 </li>
 <li>
 Familiarity with cloud platforms and deploying AI models in cloud-based environments
 </li>
 <li>
 Excellent problem-solving and analytical thinking skills with close attention to detail
 </li>
 <li>
 Excellent communication and collaboration skills in a fast-paced and collaborative environment.
 
 
 </li>
 </ul>
 
 Additional
 
 
 
 Competitive compensation
 
 
 Lunch provided daily
 
 
 Company events
 
 
 Arcade is an equal opportunity employer. We&rsquo;re committed to building a diverse, inclusive, and supportive team, and to creating a platform where anyone, anywhere, can make something meaningful.
 
 
</div>

Applied AI Engineer

OpenAI

<div>
 
 About The Team
 
 
 
 Our team brings OpenAI&rsquo;s most capable technology to the world through our developer platform: the OpenAI API. As the leading AI development platform, our API is used by millions of developers and the majority of enterprises around the world, and powers the majority of AI applications that you may use on a daily basis. Most recently, we&rsquo;ve released gpt-5, gpt-realtime, Responses API, Agents SDK, and many other products and features.
 
 
 
 About The Role
 
 
 
 We are looking for a software engineer to own the design of our APIs. Our API
 
 is
 
 our product, and as such we treat its design and development with care and intentionality. Every endpoint, every field name, and every enum value is a product interface that we want to design well. We are looking for engineers who not only love building APIs, but who will also sweat the details around API design and have a discerning taste for well designed API experience. You will play a major role in shaping the future roadmap of the OpenAI API &ndash; by both building and designing it.
 
 
 
 In This Role, You Will
 
 
 
 <ul>
 <li>
 Design and build products that we launch in API &ndash; extending existing endpoints, adding new endpoints, or rethinking our entire API suite.
 </li>
 <li>
 Play a major role in our API Review process &ndash; working with all other teams to ensure our APIs meet our design standard.
 </li>
 <li>
 Collaborate closely with the rest of the API team, our Developer Experience team, and our GTM team to make our APIs the best in the world.
 
 
 </li>
 </ul>
 
 You Might Thrive In This Role If You
 
 
 
 <ul>
 <li>
 Appreciate taste in API design &ndash; you believe there are well designed APIs and poorly designed APIs
 </li>
 <li>
 Can thrive and operate independently in a fast-paced environment with ambiguous requirements and goals
 </li>
 <li>
 Love building for other developers, and thrive on feedback from opinionated users
 </li>
 <li>
 Are an engineer at heart, but are willing to lean into product decisions.
 </li>
 <li>
 Think of APIs as ladders.
 
 
 </li>
 </ul>
 
 About OpenAI
 
 
 
 OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity.
 
 
 We are an equal opportunity employer, and we do not discriminate on the basis of race, religion, color, national origin, sex, sexual orientation, age, veteran status, disability, genetic information, or other applicable legally protected characteristic.
 
 
 For additional information, please see OpenAI&rsquo;s Affirmative Action and Equal Employment Opportunity Policy Statement.
 
 
 Background checks for applicants will be administered in accordance with applicable law, and qualified applicants with arrest or conviction records will be considered for employment consistent with those laws, including the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance for Employers, and the California Fair Chance Act, for US-based candidates. For unincorporated Los Angeles County workers: we reasonably believe that criminal history may have a direct, adverse and negative relationship with the following job duties, potentially resulting in the withdrawal of a conditional offer of employment: protect computer hardware entrusted to you from theft, loss or damage; return all computer hardware in your possession (including the data contained therein) upon termination of employment or end of assignment; and maintain the confidentiality of proprietary, confidential, and non-public information. In addition, job duties require access to secure and protected information technology systems and related data security obligations.
 
 
 To notify OpenAI that you believe this job posting is non-compliant, please submit a report through this form. No response will be provided to inquiries unrelated to job posting compliance.
 
 
 We are committed to providing reasonable accommodations to applicants with disabilities, and requests can be made via this link.
 
 
 OpenAI Global Applicant Privacy Policy
 
 
 At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
</div>

Software Engineer, API Engineer

SoFi

<div><div>Employee Applicant Privacy Notice

Who we are:
<div>
Shape a brighter financial future with us.

Together with our members, we're changing the way people think about and interact with personal finance.

We're a next-generation financial services company and national bank using innovative, mobile-first technology to help our millions of members reach their goals. The industry is going through an unprecedented transformation, and we're at the forefront. We're proud to come to work every day knowing that what we do has a direct impact on people's lives, with our core values guiding us every step of the way. Join us to invest in yourself, your career, and the financial world.
</div></div>
The role:

As a Manager - AI Software Engineer, you will play a critical, hands-on role in managing a high-performing team while building, deploying, and optimizing scalable, real-time, full-stack custom applications, from traditional workflows and user interfaces, to applications powered by the latest advances in AI. You are a seasoned and experienced full-stack engineer with deep expertise in designing and delivering software solutions from the UI to the data back-end. You roll up your sleeves to have a &quot;code first&quot; approach. You will work across cross-functional delivery teams to shape technical architecture, champion engineering best practices, lead technical design, mentor engineers, drive product management engagement, and ensure successful delivery of high-value solutions for our users.

What you'll do:
<ul>
<li>Own the end-end full-stack engineering infrastructure, and drive technical delivery from ideation and requirements decomposition through to deployment and continual improvement, ensuring alignment with product and business goals.</li>
<li>Engage with product, design, and business stakeholders to align technical strategy, drive decision-making, and deliver high-impact solutions.</li>
<li>Architect, design, and build end-to-end user-facing applications using rich interactive user-interfaces. You will remain hands-on, leveraging your expertise working with information extracted from databases and APIs (including native database functions such as Snowflake Cortex for advanced AI workloads).</li>
<li>Participate in the design of and partner with AI specialists in the implementation of production-grade, scalable multi-agentic AI applications enabling autonomous, stateful, and collaborative agent workflows for complex, real-world problem solving.</li>
<li>Manage deployment pipelines and infrastructure as code using ArgoCD, GitLab CI/CD, and AWS best practices.</li>
<li>Deploy, optimize, and monitor workflows on enterprise frameworks.</li>
<li>Automate real-time and batch data flows using orchestration tools such as Apache Airflow.</li>
<li>Lead code and design reviews, making critical technical decisions for AI-driven services.</li>
<li>Stay current with software engineering, AI, LLM infrastructure, and the evolving tooling ecosystem; generate ideas to expand product capabilities and technical reach.</li>
<li>Lead and mentor a team of talented software engineers, fostering a culture of technical excellence, ownership, and innovation.</li>
</ul>
What you'll need:
<ul>
<li>Bachelor's or Master's degree in Computer Science, Engineering, or a related technical field.</li>
<li>9+ years of professional software engineering experience, with a heavy focus on full-stack custom product delivery, including experience leading engineering teams, projects, or functions.</li>
<li>Proven track record of simultaneously delivering high-quality, production-grade, scalable, and highly available cloud-based services, and managing project and delivery milestones.</li>
<li>Solid DevOps and infrastructure-as-code experience using ArgoCD and GitLab for deployment, CI/CD, and environment management.</li>
<li>Advanced proficiency in React, Node.js, and front-end&ndash;to&ndash;back-end custom app development.</li>
<li>Extensive hands-on experience with database platforms - Snowflake strongly preferred, including advanced features, AI/ML integrations, and Snowflake Cortex.</li>
<li>Deep expertise in orchestrating real-time and scheduled pipelines with Airflow.</li>
<li>Strong communicator; able to collaborate and drive decision-making with cross-functional stakeholders, including product management.</li>
<li>Willingness to take ownership, mentor others, and champion learning and innovation within the organization.</li>
</ul>
Nice to have:
<ul>
<li>Prior fintech or high-throughput consumer product experience.</li>
<li>Exposure to cloud-native or AI workflow orchestration platforms.</li>
<li>Experience deploying and scaling LLM-powered chatbots or retrieval-augmented generation (RAG) platforms.</li>
</ul><div><div>Compensation and Benefits</div>
<div>The base pay range for this role is listed below. Final base pay offer will be determined based on individual factors such as the candidate's experience, skills, and location.</div>
<div></div>
<div>To view all of our comprehensive and competitive benefits, visit our Benefits at SoFi page!</div>
<h5 class="jobSectionHeader">SoFi provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion (including religious dress and grooming practices), sex (including pregnancy, childbirth and related medical conditions, breastfeeding, and conditions related to breastfeeding), gender, gender identity, gender expression, national origin, ancestry, age (40 or over), physical or medical disability, medical condition, marital status, registered domestic partner status, sexual orientation, genetic information, military and/or veteran status, or any other basis prohibited by applicable state or federal law.</h5>
<h5 class="jobSectionHeader">The Company hires the best qualified candidate for the job, without regard to protected characteristics.</h5>
<h5 class="jobSectionHeader">Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.</h5>
<h5 class="jobSectionHeader">New York applicants: Notice of Employee Rights</h5>
<h5 class="jobSectionHeader">SoFi is committed to an inclusive culture. As part of this commitment, SoFi offers reasonable accommodations to candidates with physical or mental disabilities. If you need accommodations to participate in the job application or interview process, please let your recruiter know or email accommodations@sofi.com.</h5>
<h5 class="jobSectionHeader">Due to insurance coverage issues, we are unable to accommodate remote work from Hawaii or Alaska at this time.</h5>
<div>Internal Employees</div>
<div>If you are a current employee, do not apply here - please navigate to our Internal Job Board in Greenhouse to apply to our open roles.</div></div></div>

AI Software Engineer Manager, Risk Engineering

Aarki

<div>
 
 Who are we?
 
 
 
 Aarki is an AI-driven company specializing in mobile advertising solutions designed to fuel revenue growth. We leverage AI to discover audiences in a privacy-first environment through trillions of contextual bidding signals and proprietary behavioral models. Our audience engagement platform includes creative strategy and execution. We handle 5 million mobile ad requests per second from over 10 billion devices, driving performance for both publishers and brands. We are headquartered in San Francisco, CA, with a global presence across the United States, EMEA, and APAC.
 
 
 
 The role?
 
 
 
 We are seeking a motivated and detail-oriented Machine Learning Engineer to join our team. As an ML Engineer, you will be involved in designing and implementing machine learning models and data pipelines to enhance our programmatic demand-side platform (DSP). You will work closely with Senior MLE and other team members to drive impactful machine learning projects and contribute to innovative solutions.
 
 
 
 What will you do?
 
 
 
 <ul>
 <li>
 Support the development of machine learning models to address challenges in programmatic advertising, such as predicting user responses, forecasting bid landscapes, and detecting fraud.
 </li>
 <li>
 Collaborate with senior data scientists and cross-functional teams (product, engineering, and analytics) to integrate models into production workflows.
 </li>
 <li>
 Analyze the impact of integrating new data sources and features into our models.
 </li>
 <li>
 Build and maintain data pipelines to process and prepare large datasets for model training and evaluation.
 </li>
 <li>
 Contribute ideas and assist in testing new tools, methodologies, and technologies to improve our machine learning capabilities.
 </li>
 <li>
 Document experiments, assumptions, and outcomes; maintain reproducibility
 
 
 </li>
 </ul>
 
 What are we looking for?
 
 
 
 <ul>
 <li>
 Bachelor&rsquo;s degree in Mathematics, Physics, Computer Science, or a related technical field.
 </li>
 <li>
 At least 2 years of professional experience in machine learning, statistical analysis, and data analysis.
 </li>
 <li>
 Experience with machine learning techniques such as regression, classification, and clustering.
 </li>
 <li>
 Proficiency in Python and SQL and familiarity with big data tools (e.g., Spark) and ML libraries (e.g., TensorFlow, PyTorch, Scikit-Learn).
 </li>
 <li>
 Strong grasp of probability, statistics, and data analysis principles.
 </li>
 <li>
 Ability to work effectively in a team environment, with good communication skills to explain complex concepts to diverse stakeholders.
 
 
 </li>
 </ul>
 Nice-to-Have
 
 
 <ul>
 <li>
 Familiarity with system programming languages including C++ and Rust is a plus.
 </li>
 <li>
 Exposure to online inference systems, gRPC/REST model endpoints, or streaming features (Kafka/Flink)
 </li>
 <li>
 Ad-tech familiarity: auction dynamics, pacing, fraud signals, creative personalization.
 </li>
 </ul>
</div>

Machine Learning Engineer

Genentech

<div><div><div>THE POSITION</div>
A healthier future. It&rsquo;s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That&rsquo;s what makes us Roche.
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche&rsquo;s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&amp;D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
Within the CoE organization, the Data and Digital Catalyst organization drives the modernization of our computational and data ecosystems and integration of digital technologies across Research and Early Development to enable our stakeholders, power data-driven science and accelerate decision-making.
The Opportunity:
The Research &amp; Early Development Senior Principal Engineer/Architect is a well-established, highly capable and credible architect who will contribute to and drive the implementation of a modern enterprise architecture strategy across Research and Early Development to build a modern, cohesive, scalable, and flexible technology stack that supports the ecosystem of platforms and systems as well as enabling seamless data flow and integration. In this role you will be the key architectural driver responsible for translating our long-term vision into pragmatic execution, enabling critical scientific use cases today while building the foundation for the next generation of automation, AI-enabled biology and drug discovery.
You will contribute to the development of architecture principles and frameworks that underpin the delivery of seamless digital journeys and modern corporate capabilities. You will leverage your understanding of Pharma Research &amp; Early Development to shape and guide how our core systems and platforms are built to power scalable research infrastructure, ensure operability, and enable cutting edge computational capabilities. The role balances scientific-centric design with robust enterprise integration, data privacy, and regulatory compliance. We strive to transform our digital landscape in order to advance the delivery of more innovative and transformative medicines for patients worldwide.
In this role, you will partner with scientists and engineers to shape transformation programs, digital service enhancements, and continuous improvement initiatives. You will support enterprise-wide architecture governance and decision making.
You will make pivotal contributions to the future of the CoE and Research and Early Development by:<ul><li>
Contributing to the definition and building of a modern enterprise architecture vision with standards, governance, and reusable design patterns.</li><li>
Driving the adoption of modern architectural principles and reference architectures that facilitate integration, automation, and AI/ML enablement across the organization.</li><li>
Evaluating and embedding cutting-edge technologies and forward-thinking architectural strategies to support future research and early development needs.</li><li>
Leading the transformation of bespoke legacy systems and complex tech stacks into modern, modular, and service-oriented ecosystems.</li><li>
Establishing best practices for compliance, data security, and privacy, while fostering a culture of collaboration with partners across Roche Informatics, gRED, and pRED.</li><li>
Driving the architecture for large-scale strategic initiatives and application development projects to facilitate the effective acquisition, processing, and sharing of scientific information.</li></ul>
Who You Are:
We are looking for a leader with the following qualifications and experience:<ul><li>
You hold a BSc degree (MS or PhD preferred) in a scientific or technical field with 8+ years of experience (Senior Principal Engineer); BSc degree (MS or PhD preferred) with 10&ndash;12+ years of experience (Enterprise Architect).</li><li>
Experience as a matrix leader is a plus.</li><li>
You have proven experience in enterprise and solution architecture, including translating strategic vision into actionable solution designs and implementation blueprints in large, complex, regulated organizations, ideally in the healthcare or biotech domain.</li><li>
You possess strong knowledge in enterprise systems, data, and information architectures across cloud, hybrid, and on-premise environments.</li><li>
Familiarity with AWS is a plus.</li><li>
You have a strong understanding of modern digital technologies, including microservices, event-driven systems, AI/ML platforms, and modern DevSecOps practices.</li><li>
You have an understanding of how data is generated, processed, and leveraged to inform scientific decisions in Pharma Research &amp; Early Development.</li><li>
You have demonstrated experience in mentoring, influencing, and guiding technical peers and collaborating effectively with multidisciplinary teams.</li><li>
You have a proven ability to design and drive the delivery of complex computational projects, ensuring efficiency, scalability, and reproducibility.</li><li>
You are a strong communicator with the ability to clearly document and present architectural designs and options to technical teams and business stakeholders.</li></ul>
Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week.
The expected salary range for this position based on the primary location of South San Francisco, California is $189,300 - $351,500 (Senior Principal Engineer) and $217,400 - $403,700 (Enterprise Architect). Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
#LI-JD1
#ComputationCoE
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.</div>
<div><div>JOB FACTS
</div><div><div><ul><div>Job Sub Category
Research Informatics
</div><div>Schedule
Full time
</div><div>Job Type
Regular
</div><div>Posted Date
Mar 2nd 2026
</div><div>Job ID
202602-105168</div></ul></div></div></div></div>

Research & Early Development Enterprise Architect

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